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BmK IT2 is worthy of being considered to be a kind of new algesia peptide drug.

BmK粗毒和BmK I诱导的大鼠脊髓背角氨基酸类神经递质的释放采用微透析采样与高效液相色谱荧光检测技术,分析BmK粗毒和其主要致死成分BmK I诱发炎症痛过程中同侧脊髓背角氨基酸含量的动态变化。

In long interval priming-boosting regimen, higher levels of anamnestic antibodies were produced and, the Thl type response became more evident.

较长的免疫间隔有利于产生更高水平的回忆性抗体,同时也更加倾向于病毒所诱导的免疫应答即Thl型应答。

We observed the crystals under H-500 scanning electron microscope.Results The producing ways of tunica vasculosa microangiogenesis of rat's crystal:(1)single-directional germination;(2)bi-directional germination;(3)collagen and pericyte mediated germination;(4)angioblast inducted germination;(5)germ germinated.

结果 大鼠晶体血管膜血管发生方式:(1)单向芽生方式;(2)双向芽生方式;(3)胶原及周皮细胞介导的芽生方式;(4)血管母细胞诱导的芽生方式;(5)芽生芽的方式。

Qingyangshenylycosides is a mixture of several related compounds derived from the root of a Traditional Chinese Medicine, Cynanchum Otophyllum. Pharmacological characterization of the compounds indicated that the drug had a significant antiepileptic and anticonvulsant activity on kindling, rat audiogenic seizures and ferrous sulfate-induced epilepsy.

青阳参总甙(Qingyangshenylycosides,QYS)是萝摩科鹅绒属植物青阳参根粉提取物,已有动物实验表明QYS对大鼠听源性惊厥(audiogenic seizure,AGS)发作、&点燃&效应以及硫酸亚铁诱导的癫痫发作具有明显的对抗作用,表现出显著的抗癫痫效应。

Activity of liver sod in high-dose of alcoholic extracts of averrhoa carambola l.root group significantly increased(p<0.05), while concentration of mda in liver decreased markedly(p<0.01).conclusionthe alcoholic extracts of averrhoa carambola l.root could relieve the reaction of lipid peroxide and has significant hypoglycemic effect in stz-induced diabetic mice. it is a potential hypoglycemic agent of treatment diabetes and its complication.

结论阳桃根醇提物能够减轻stz诱导的糖尿病小鼠脂质过氧化反应,降低血糖,是一种具潜在开发意义的治疗糖尿病及其并发症的药物。

ConclusionThe lentivirus RNAi vector of TREM-1 was constructed successfully. The lentivirus RNAi vector of TREM-1 can inhibit the expression of TREM-1 in the murine endotoxemia model caused by Bacteroides fragilis LPS.

成功构建了小鼠TREM-1基因RNAi慢病毒载体,所构建的慢病毒载体能够抑制脆弱类杆菌内毒素所诱导的TREM-1的表达。

Mannitol challenge also has a tussive effect that is independent of bronchoconstriction, suggesting different physiologic pathways.

甘露醇同时具有诱发咳嗽的作用,该作用不依赖于支气管收缩,表明该作用与其诱导的支气管反应具有不同的生理学作用通路。

To investigate the effect of Jiangu granula on the apoptosis of newborn rat calvaria osteoblast induced by TNF-ɑ in vitro.

目的 探讨健骨颗粒含药血清对TNF-ɑ体外诱导的新生大鼠成骨细胞凋亡的影响;进一步揭示健骨颗粒改善骨质疏松模型鼠骨量的可能机制。

The present study was designed to investigate whether histamine is involved in the protective effect of carnosine on Aβ42-induced impairment in differentiated PC12 cells.

因此本实验的主要目的是检测肌肽对Aβ42诱导的神经兴奋性损伤是否具有保护作用,肌肽-组胺酸-组胺通路是否参与其保护机制,谷氨酸含量,NMDA受体表达及功能在这一过程中是否受到影响,最终阐明肌肽保护作用的具体机制。

Objective: To study the role of anti-apoptotic protein Mcl-1 in bile salt-induced chemoresistance of hepatocellular carcinoma cells.

的:探讨抗凋亡蛋白Mcl-1在GCDA诱导的肝癌细胞耐药中的作用及其机制。

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