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It implies that the induced antibacterial substance in the blowfly should possessed stronger antibacterial activity in acid condition. Bathing at 80 ℃ for 1 to 3 min and then centrifuging can get rid of unwanted proteins in a large extent. Maybe the two special bands are the components of the antibacterial peptides induced in the blowfly.

针刺诱导的丝光绿蝇抗菌肽在酸性条件下抑菌活性更强,分离时血淋巴预处理采用80℃水浴1-3min去杂蛋白效果较好,诱导的血淋巴100℃处理3和5min即丧失抗菌活性,电泳显示缺少2条区带,此2条差异区带可能为抗菌肽组分。

Our results indicate that 1 NSC606985, at nanomolar level, can effectively induce apoptosis in AML cells NB4 and U937 and significantly inhibit the proliferation without cell death in breakpoint cluster region–Abelson murine leukemia kinase-carrying leukemic K562 cells; 2 At such low concentrations, this agent also significantly inhibits the clonogenic activity of hematopoietic progenitors from patients with AML; 3 For apoptosis induction, NSC606985 rapidly induces the proteolytic activation of protein kinase Cδ with loss of mitochondrial transmembrane potential and caspase-3 activation; 4 Co-treatment with rottlerin, a PKCδ-specific inhibitor, completely blocks NSC606985-induced mitochondrial m loss and caspase-3 activation, while the

结果显示:(1)纳摩尔浓度的NSC606985即可有效诱导AML细胞系NB4和U937细胞凋亡并显著抑制含有bcr-abl融合蛋白激酶的K562细胞的增殖;(2)低浓度的NSC606985也显著抑制来自AML病人骨髓的新鲜白血病细胞的克隆形成能力;(3)除了迅速诱导线粒体跨膜电位的崩塌及Caspase-3的活化外,NSC60698也导致蛋白激酶Cδ的水解激活;(4)PKCδ特异的抑制剂rottlerin能够完全抑制NSC606985诱导的线粒体跨膜电位的崩塌和Caspase-3的活化,而Caspase-3特异的抑制剂z-DEVD-fmk仅能部分削弱PKCδ的活化及细胞的凋亡;(5)以移植PML-RARα转基因小鼠产生的白血病细胞建立的模型研究了该化合物对白血病可能的治疗作用。

The results showed that both sporophores and stromata of Cordyceps militaris had high content of polysaccharide. And polysaccharide content in stromata was 2-4 times higher than that in sporophores. CMPS could decrease the AST, ALT and MDA levels, and restore GSH-Px content and cell viability remarkably in supernatant of cultured hepatocytes injured by CCl4 induction.

结果表明:蛹虫草的子实体和基质都含有丰富的多糖,其中基质中的多糖含量最高,约为子实体的2~4倍;CMPS可明显降低由CCl4诱导的损伤肝细胞培养上清液中谷草转氨酶、谷丙转氨酶的活性水平和丙二醛的含量水平,显著提高由CCl4诱导的损伤肝细胞培养上清液中谷胱甘肽过氧化物酶活性和诱导损伤肝细胞的存活率。

NodD binds to and bends target promoters through anchoring two tandem and individual specific DNA sites. NodD functions as a tetramer, which has a V-shaped main body. Tetrameric NodD is to change its own conformation rather than its oligomeric forms in response to small signal molecules. The specific interaction between each NodD DNA-binding domain and each specific DNA site does not alter itself in spite of naringenin induction, and the induced conformational change is transferred from protein to DNA. Only the DNA conformation incited by induced NodD is competent for RNA polymerase to form the transcriptional open complex. It cannot be excluded that NodD may have protein-to-protein contacts with RNA polymerase, and that the NodD conformational change may also directly contribute to the transcriptional open complex formation. However, the NodD conformational change itself cannot serve as the determinant of the transcriptional molecular switch.

通过研究,我们提出了初步的NodD操纵子激活模型:第一,四聚体是NodD蛋白的功能单位,它通过铆钉两个串联的相对独立的DNA靶位点结合被诱导的启动子;第二,小分子配基的结合是改变NodD四聚体的构象而不是引发不同形式的寡聚体,在我们的模型中,NodD四聚体缩小其V形主体的弯折角,进而缩短其DNA结合功能域的间距;第三,小分子信号的诱导并没有改变NodD的DNA结合域和其DNA靶位点的相互作用,NodD的构象改变由蛋白质经其双铆钉位点传递给DNA;第四,只有诱导状态的NodD激发的DNA构象才能有效地使RNA聚合酶形成转录开放复合物;第五,不排除NodD与RNA聚合酶可能有直接的相互接触位点,不排除NodD构象的改变可能直接有利于RNA聚合酶形成转录开放复合物,但是我们认为NodD构象改变本身不是充当转录激活开关的决定因素。

It uncouples oxidative phosphorylation but, unlike the aflatoxins, does not induce mitochondrial swelling or hinder Ca2+-induced swelling of mitochondria.

它解开氧化磷酸化但不像黄曲霉毒素类,不能诱导线粒体肿胀或阻止Ca2+诱导的线粒体肿胀。

Subthreshold TTT may induce Hsp70 expression in the retina, choroids and laser induced CNV in rats.

阈下能量TTT可诱导大鼠视网膜、脉络膜和激光诱导的CNV表达Hsp70。

The results suggest that the EGFR clustering induced by 50 Hz MF depends on intact lipid rafts on cellular membrane, and the ASM might participate in the process of EGER clustering.

工频磁场诱导FL细胞膜表面EGFR发生聚簇与脂筏结构密切相关,ASM有可能参与了工频磁场诱导的受体聚簇及/或信号转导过程。

Epicotyls were cutted longitudinally and cultured in the dark first,on the MS basal medium with 3 mg/L 6-BA and 30 g/L sugar,100% adventitious shoot induction and an average of 33.8 shoots per explant were obtained.

上胚轴纵切结合前期暗培养,在MS附加6-BA 3mg/L、蔗糖30g/L 培养基中,不定芽诱导率为100%,每个外植体平均诱导的不定芽数达33.8

The experimental results showed:The half-solid culture clearly resulted in better inducing effect than the solid culture.

试验表明,两种培养基以半固体方式培养诱导的效果好于固体方式培养诱导效果。

PTAH staining for striated muscle illustrated that 70-80% differentiated MSCs could be stained positively.

体外5-aza诱导分化MSCs后,应用磷钨酸-苏木素作横纹肌染色,发现所诱导的MSCs染色阳性率达70-80%。

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In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国,慢性酒精中毒,肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题,你可以随时联系我。

Very pretty, but the airport looks more fascinating The other party wisecracked.

很漂亮,不过停机坪更迷人。那人俏皮地答道。