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Effects of Simvastatin on the Transdifferentiation of Renal Tubular Epithelial Cells Induced with High Glucose UANG Xiao-xia,KE Chang-bin,ZHANG Qing-hong,ZHANG Jian-e*(Department of Nephrology;Department of Anesthesia,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei 442000,China)Abstract:Objective To investigate the effects of simvastatin in renal tubular epithelial cells transdifferentiation induced with high glucose.

作者:黄晓霞,柯昌斌,张庆红,张建鄂*作者单位:郧阳医学院附属太和医院肾病内科;麻醉科,湖北十堰 442000 目的:观察辛伐他汀对高糖诱导的肾小管上皮细胞转分化的作用。

Prdetreatment of unelicited MPM with IL-6 enhanced TG replication in a dose-dependent manner.

IL-6可促进TG在MPM内的增殖,并能逆转IFNγ诱导的MPM抗TG效应。

The immunofluorescence was developed with the mouse anti-VP4 serum. The results indicated that there was green-yellow fluorescence on the cell surface of pPG-1-VP4 and pPG-1-VP4-LTB when induced. The cells uninduced did not display an immunofluorescence reaction and were dyed red by Evans blue.

通过间接免疫荧光方法鉴定,pPG-1-VP4和pPG-1-VP4-LTB的菌体表面均能看到黄绿色荧光,而未诱导的菌体则没有荧光反应,且细胞被伊文思蓝染成红色。

Moreover, using the in vilro DNA-matrix binding assay results showed that HS2, HS3 and HS4 core DNA sequences were unable to bind to the nuclear matrix isolated from uninduced HEL cells; in addition, HS2 core DNA sequence was capable of binding to the nuclear matrix prepared from Hu-induced HEL cells, while both HS3 and HS4 can not bind to it.

同时,运用核基质与DNA体外结合实验表明,这些核心DNA序列均不能与非诱导的HEL细胞内的核基质结合。

Conc1usion: CD4(superscript +)T cells subset may bear a part in protection induced in mice by mixed recombinant BCG-Em Ⅱ/3 and BCG-Em14-3-3 vaccine against challenge with Em protoscoleces.

CD4T细胞亚群在多房棘球绦虫重组BCG-Eml4-3-3疫苗诱导的小鼠抗Em原头节攻击感染的保护性免疫机制中起一定作用。

Previous studies have indicated that intrathacheal administration of rhSOD is well tolerated with significantly increasing in SOD concentrations and activity in serum,tracheal aspirates and urine within 3 days in premature infants with RDS.

已有研究表明,rhSOD可减轻内毒素所诱导的肺损伤;且rhSOD气管内给药具有安全、吸收快、半衰期长的特点,还具有抗炎作用。

Extract of Ginkgo biloba attenuates high glucoseinduced apoptosis of endothelial cells.

银杏叶提取物降低高糖诱导的血管内皮细胞的凋亡。

The biological characteristics of transfected cells and its original ceils were compared.

目的研究SV40 T基因对其诱导的永生化细胞系细胞表型的影响。

The strength and rigidity of the femurs in 16 rabbits were measured systematically.

结果:(1)激素诱导的兔股骨头坏死模型组其股骨的强度和刚度明显下降,低于正常组和治疗组(P<0.05)。

Filtrates of ultrafiltration within different membrane cut-off ranges were used to test the activity of growth inhibition from WEJFS.

爱玉子种子水萃物对DNA和Clone 9细胞具有保护作用,包括降低氢氧自由基诱导的DNA损伤,与抑制过氧化氢造成Clone 9细胞的死亡。

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