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Pharmacological activity test in vitro All target compounds and PFT-αwere assessed for their ability in vitro to protect PC12 cells against H2O2 induced apoptosis through MTT methods. The results suggested that compound 3a, 3b and 3c have dual activity of neurotrophy and apoptosis inhibiting activity on oxidation stress damaged PC12 cell.

三、抗神经细胞凋亡实验对目标化合物都进行了体外药理活性试验:以H2O2为凋亡诱导剂损伤PC12细胞构建氧化应激损伤的凋亡细胞模型,用MTT法考察目标化合物对H2O2诱导的神经细胞凋亡的抑制作用。

The results indicated that 3 chemicals could greatly enhance resistance of potato tuber to early blight low concentrations. Protection rates induced by phenol (1mmol/L), benzoic acid (0.01mmol/L), and paraaminobenzoic acid (5mmol/L) were 43.21%, 40.72%, and 28.75%, respectively.

结果表明,供试的3种化合物均在较低浓度下具有较强的诱导抗病作用,苯酚、苯甲酸和对氨基苯甲酸分别在1,0.01和5mmol/L时诱导的保护率最高,分别达到43.21%,40.72%和28.75%,均与对照差异极显著。

Exposure of naive CD4〓T lymphocytes to superantigen induces a strong proliferative response. Prolonged exposure or subsequent restimulation of the responding CD4〓T cell population with superantigen leads to the apoptotic events of activation-induced cell death.

幼稚的〓细胞暴露于超抗原可诱导强烈的增殖反应,继续延长暴露或再次刺激应答〓细胞可导致活化诱导的细胞死亡。

However,compared to Cd~(2+) stress alone, treatment of SNP+Cd~(2+) caused more increases in SOD,CAT and POD activities, a decrease of H_2O_2 level and MDA content in leaf and root ofmung bean seedlings. These results indicated that exogenous NO induced increases inSOD, CAT and POD activities, which scavenged H_2O_2 and resultantly inhibitedmembrane lipid peroxidation in leaf and root of mung bean seedlings under Cd~(2+) stress.

说明NO通过诱导膜保护酶活性的提高,降低了活性氧水平,从而使Cd~(2+)胁迫诱导的膜脂过氧化程度降低,这可能是外源NO明显缓解Cd~(2+)胁迫抑制绿豆幼苗生长发育的原因之一。

We propose that dexfenfluramine can also inhibit hypoxia-induced pulmonary vascular remodeling via SERT activity and inhibition of hypoxia-induced p38 mitogen-activated protein kinase.

因此我们认为右旋酚氟拉明也能通过改变SERT的活性抑制缺氧诱导的肺血管重构和抑制缺氧诱导的p38细胞分裂素活化蛋白激酶

Calcium ionophore-induced tryptase release was inhibited 60% and 69% by 10 and 50 microM of DL, respectively, and anti-IgE-induced tryptase release was inhibited 33%, 47% and 66% for 1, 10 and 50 microM of DL.

研究发现浓度分别为1、10和50mM的DL分别使钙离子载体诱导的LTC4释放下降29%、35%和39%,分别使IgE诱导的类胰蛋白酶释放下降33%、47%和66%。

The DNA relative content of large unreduced pollen grains induced by colchicine was determined quantitatively with laser scanning confocal microscopy using the normal-sized pollen grains as control. The results suggest that the large unreduced pollen grains are diploid.

以正常花粉作对照,用激光扫描共聚焦显微镜对经秋水仙碱处理诱导出的大花粉进行了DNA含量的定量测定,初步确认该试验诱导的大花粉是一种二倍体花粉。

Part Ⅳ Further Studies on Effects of Anti-S. japonicum Egg Granuloma and Hepatic Fibrosis Induced by SCP Combining Reagent Further to probe the effects of anti-S. japonica and antiS. japonicum hepatic fibrosis induced by shark cartilage powder cooperating"425"preparation.

第四部分 SCP合剂诱导的抗血吸虫卵肉芽肿及抗肝纤维化效应的进一步研究为进一步探讨鲨鱼软骨粉联用&425&制剂诱导的抗血吸虫卵肉芽肿及抗血吸虫性纤维化效应。

The models of the ear swilling of mice and paw edema of rats were adopted to assay anti-inflammatory effect. Results 5-ASA(ig,75,150 and 300 mg.kg-1,for 3 d)significantly reduced the ear swelling of mice and the paw edema of rats and also decreased the writhing. 5-ASA at the dose of 300 mg.kg-1 ig,prolonged pain latency on hot-plate reaction.

结果 5-ASA片剂3种剂量(75、150及300 mg.kg-1,ig×3 d)对二甲苯诱导的小鼠耳肿胀度及蛋清诱导的大鼠踝关节肿胀度均有明显抑制作用;以上剂量还可明显抑制小鼠扭体反应,大剂量还可延长小鼠热板的舔足反应潜伏期。

In our study, we first designed the high and low-degree lens according to the real diopters of guinea pigs, and explored the sensitivity of guinea pigs to lens-induction.

本研究中,我们首次根据豚鼠眼的实际屈光度数设计不同高低度数的诱导透镜,观察豚鼠眼对透镜诱导的敏感性。

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