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In order to understand the mechanism of anti-inflammatory effect of PA and carvacrol, the superoxide dismutase, glutahoine reductase, glutahoine peroxidase activities in liver and malondialdehyde , cyclooxygenase 2 (COX-2), tumor necrosis factor-α levels were eveluated. Also observed inducible nitric oxide synthase and cyclooxygenase-2 (COX-2) expression and the pathological histology in λ-carrageenan induced paw edema in mice.

本研究首先以醋酸扭体试验评估左手香水抽提物及其活性成分香芹酚是否具有镇痛效果,以福马林舔足试验辨别其镇痛作用是在周边或是中枢,再以λ-角叉菜胶诱导小鼠足跖肿胀试验探讨其抗发炎作用,并分析其肝脏组织中的超氧歧化酶、麸胱甘肽还原酶、麸胱甘肽过氧化酶活性、发炎足跖组织中的脂质过氧化指标产物丙二醛、肿瘤坏死因子-α及环氧化酶-2之含量变化,观察诱导型一氧化氮合成酶及环氧化酶-2之蛋白质表现量,并将肿胀足跖做病理切片观察之,以探讨左手香水抽提物及香芹酚之抗发炎机转。

By employing such a method, 5 series of elastomers, including natural rubbers, elastomeric polyester fibers and ethylene-octene, ethylene-methyl acrylate as well as SIS triblock copolymers, were investigated with the purpose of studying elongation induced phase structure and mobility changes of the samples. For NR samples, it was demonstrated that there exists a small amount of crystals at RT even for unelongated samples. For both NR and the soft segment of PEE, with the increase of elongation ratio, the elongation-induced crystallinity increases almost linearly in a certain region of R, in accord with the increase of the lamellar thickness of the crystals; The behavior of ethylene copolymers, in terms of elongation induced morphorpholgy changes, are quite different from NR and PEE. The crystals are found to be gradually destroyed with the increase of R, with accord with the decrease of the lamellar thickness; The motional behavior of the soft segment of SIS, changes from "liquid" to "solid", in terms of 13C NMR spin-lattice relaxation.For many of the aformented samples, the dependence of 13C spin-lattice relaxtion time T1 on R are different for different groups, indicating that the changes of mobility at MHz frequency region with elongation are different for different groups.

通过对天然橡胶、聚醚酯嵌段共聚物、乙烯-辛烯共聚物、乙烯-丙烯酸甲酯共聚物、SIS等高分子弹性体样品聚集态结构和分子运动的研究,获得了一些新的实验结果,如:给出了确切的实验证据,证明了室温下未拉伸的天然橡胶样品中存在着微量的结晶;发现随着拉伸比增加,天然橡胶及聚醚酯样品的软段部分会出现拉伸诱导的结晶,且结晶度在一定范围内呈现近似线性的增加,所形成晶片的厚度也随之逐渐增加;而乙烯共聚物随着拉伸比的增加,原有的结晶会被逐渐破坏,晶片厚度逐渐变薄,结晶中的缺陷逐渐增加;随着拉伸比的增加,SIS中PI软段部分的核磁共振弛豫行为会出现从液态到固态的转变等;在对上述多个体系的研究中,还发现不同基团的自旋-晶格弛豫时间随着拉伸比呈现不同的变化趋势,表明不同基团的高频运动随拉伸比增加有不同的变化规律。

Two models have been proposed to explain molecular mechanism of Dkk's inhibition role in canonical Wnt pathway: in the first model, Dkk1 competes for binding of Wnt co-receptor LRP6; in the second model, Dkk1 can form a ternary complex with LRP6 and Kremen at the presence of Kremen, and triggers the endocytosis of this ternary complex quickly. The controversies between these two models exist during these years.

现今有两种模型分别解释Dkk抑制经典Wnt信号的分子机制:在第一种模型中,一些研究者认为Dkk1主要通过在细胞外与配体Wnt竞争受体LRP6从而抑制Wnt信号;在第二种模型中,另一些研究者们则认为在Kremen存在的情况下,Dkk1通过诱导形成Dkk1-LRP6-Kremen三元复合物,并迅速诱导这个三元复合物的内吞从而发挥抑制功能。

The qualitative analysis of the volatiles emitted from tea plants infested by Ectropis obliqua Prout with GC-MS or zNoseTM showed the similar results, however the relative contents of-3-hexen-1-ol,benzyl nitrile,indole,-caryophyllene obtained from both showed a certain difference.

结果表明:GC-MS与zNoseTM对茶尺蠖取食诱导的茶树挥发物的定性分析结果差别不大;但两者测定茶尺蠖取食诱导的茶树挥发物中顺-3-己烯醇、苯乙腈、吲哚、反-石竹烯等4种组分的相对含量有一定差异。

Methods Autologous BMMSC of New Zealand rabbits were acquired and induced into chondrogenic differentiation by adding transforming growth factor-β1 (TGF-β1), dexamethasane and ascorbic acid in vitro. Then the chondrocytes were implanted onto novel polymeric scaffolds made by Poly (dl-lactide-co-glycolide) embedding with chitosan nonwoven cloth. The tissue engineering cartilaginous grafts composed of chondrogenetic BMMSC/scaffolds were finally transplanted into the defects of ear cartilage in rabbits of the experimental group.

取新西兰大白兔BMMSC体外培养扩增,以含转化生长因子(TGF-β1)、地塞米松和维生素C的培养液做诱导培养,实验组以诱导后的软骨细胞与聚丙交酯-乙交酯共聚物Poly(dl-lactide-co-glycolide)包埋甲壳胺无纺布的新型支架形成复合物修复兔自体耳廓软骨缺损;对照组以PLGA/甲壳胺无纺布支架修复兔耳廓软骨缺损。

Fourteen sediment samples with different content of Fe〓O〓 were collected from lower reach of the Liao River in China. The photodegradation of γ-hexachlorocyclohexane on the sediment surfaces was investigated to observe the effects of Fe〓O〓 and other photoinducable substances, such as TiO〓 and organic substances, on photodegradation of γ-HCH.

从辽河新民段采集了14种具有不同含量的Fe〓O〓的天然沉积物,为了探讨沉积物中Fe〓O〓和其它具有光诱导和光催化能力的物质如TiO〓和有机质成分对沉积物表面上的林丹的光解的影响,研究了γ-HCH在这些沉积物表面上的光解动力学。

Photodissociation spectroscopy of the complexes Mg~+-NCSCH_3 Mg~+-S_2(CH_3_2 in the spectral region of 230-440nm was oberserved. As to Mg~+-NCSCH_3 of photo-induced reaction, there were three channels. And there are the products Mg~+ from nonreaction quenching and reactive products Mg~+NC, Mg~+NCS in the reaction throughout the whole wavelength range.

观察了复合物Mg~+-NCSCH_3Mg~+-S_2(CH_3_2在230~440nm范围的光解离光谱,在此波段内的复合物光诱导产物的质谱显示,对Mg~+-NCSCH_3:光诱导反应有三个通道,存在着非反应猝灭产物Mg~+和反应产物Mg~+NC、Mg~+NCS。

Schizophyllum commune AS 5.391 can produce CDH and the CDH production is induced by cellulosic substrates. Cotton is the best inducer for CDH production.The lignin model compound veratryl alcohlo has no effect on CDH production.

裂褶菌 Schizophyllum commune AS 5.391可以合成纤维二糖脱氢酶,CDH的合成受底物的诱导,在以纤维素为底物的培养基中才能合成该酶,随着纤维素结晶度的增加诱导作用也越强,以棉花的为最好。

Allogeneic and syngeneic fresh bone, autolyzed antigen-extracted bone, bone matrix gelatin, demineralized bone matrix were implanted into the muscle pouch of mice, at different times after implantation, the immunological, histological and alkaline phosphatase assay were conducted. The results revealed that all four kinds of allogeneic implants activated specific cellular and humoral immune responses, most notably in fresh bone group, the AAA, BMG and DBM inhibited the proliferation of the lymphocytes in vitro and BMG had the most powerful inhibiting action, allogeneic AAA, BMG and DBM might induce heterotopic osteogenesis in vivo, however, there were obvious difference in ALP and histomorphometry between allografts and isografts.

在小鼠肌肉内植入同种异体或同系新鲜骨、自消化抗原去除骨、骨基质明胶、脱钙骨基质,术后免疫学、碱性磷酸酶、组织学检查发现:4种同种异体植入物均可引发特异性细胞免疫反应和体液免疫反应,其中以新鲜骨移植引发的免疫反应最为显著;自消化抗原去除骨、骨基质明胶、脱钙骨基质在体外具有抑制淋巴细胞增殖的作用,骨基质明胶对淋巴细胞增殖的抑制作用最显著;同种异体与同系4种植入物在体内成骨活性有显著差异;自消化抗原去除骨、骨基质明胶、脱钙骨基质均有异位诱导成骨活性,其中骨基质明胶骨诱导活性最佳。

The thesis mentioned that the conformation of lipase molecular can be induced by substrate to be an activated one in organic phase through constructing a water-in-oil micro-emulsion system. The activated conformation was recorded using high cross linking degree polymer. The effect of inducement on the activity of recorded lipase polymer was studied, the catalyzed property of recorded lipase polymer in water phase was investigated, and the fluorescence spectrum of lipase solution and recorded lipase polymer under different kinds of denaturalized circumstance were analyzed.

本文提出通过构建油包水型微乳体系,使酶分子能够在有机相中被反应底物诱导出活性构象,利用高交联度聚合物对该构象进行刻录,比较了底物诱导对刻录酶活性的影响,考察了刻录酶在水相中催化特性,并对脂肪酶溶液和刻录酶聚合物在各种变性条件下的荧光光谱进行分析。

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The reasons of iron ions content overproof in grade Ⅱ desalting water system,such as variation water quality,contamination of regenerant , operation adjustment of pretreatment system and switching operation of bed were discussed.

对二级脱盐水系统中铁离子含量超标的原因,如来水水质发生波动、再生剂受到污染、预处理系统操作调整、床体运行切换等进行了论述。

You were hired to drum up new business, so go and do it.

公司雇你招徕新业务,你就做你的事好了。

Who is in possession of this?

这是谁的?