诱导抵抗

Objective: To investigate the morphologic and hormonal changes in the ovarium of polycystic ovarian syndrome rat model induced by dehydroeplandrosterone,and the relationship between PCOS and insulin resistance.

提要 目的：研究脱氢表雄酮诱导SD幼年雌性大鼠多囊卵巢综合征动物模型的卵巢形态学及性激素变化，同时探讨其与胰岛素抵抗方面的关系。

Objective: To investigate the morphologic and hormonal changes in the ovarium of polycystic ovarian syndrome rat model induced by dehydroeplandrosterone,and the relationship between PCOS and insulin resistance.

目的 ：研究脱氢表雄酮诱导SD幼年雌性大鼠多囊卵巢综合征动物模型的卵巢形态学及性激素变化，同时探讨其与胰岛素抵抗方面的关系。

the morphologic and hormonal changes of the ovarium in the dehydroeplandrosterone-induced rat PCOS model were similar to those of the patients with PCOS,and the insulin resistance was observed. It was proved to be a ideal PCOS amimal model.Key words DHEA;PCOS; Animal model.

DHEA诱导SD幼年雌性大鼠PCOS动物模型卵巢病理改变及血内分泌改变与PCOS病人相似，并存在胰岛素抵抗现象，是较理想的PCOS模型。

Outcome:(1) Acute ischemic damage may induce the expression of c-fos protein in Cerebral Cortex quickly. Also, the expression increases by the ischemia time delay. It may hint that ischemia injury can rise the ability of nerve cells to tolerate ischemia and anoxia. And the expression level of c-fos can be up-regulated by putting blood of 12 hand Jing Points. So we think that treated by this therapy can rise the irritability of brain to resist the development of ischemia and enhance the ability to plerosis.(2) Acute ischemic damage may induce the expression of HspVO in Cerebral Cortex quickly. Also, the expression increases by the ischemia time delay. It may hint that ischemia injury can rise the ability of nerve cells to tolerate ischemia and anoxia.

三 结果(1)急性缺血性脑损伤可快速诱导c-fos蛋白在皮层缺血区脑组织的表达，其表达有随缺血时间延长而逐渐增多的趋势，提示脑的缺血性损伤可应激性地增强神经细胞对缺血、缺氧的耐受和适应能力，而应用井穴放血的干预治疗可明显上调缺血区皮层脑组织c-fos的表达水平，进一步增强脑组织对抗缺血性损伤的应激能力，抵抗缺血性脑损害的进一步发展。

Results Blood sugar level was decreased by Merine collagen peptide ,but The blood sugar did not change significatively during the experiment .

目前认为，糖尿病的发生机制与胰岛素抵抗和机体高血糖、高血脂等因素诱导的抗氧化应激功能失调有显著的相关性。

Objective To study effects of PKC on signal transduction in palmitate-induced hepatic insulin resistance.

目的 探讨蛋白激酶PKC在软脂酸诱导的肝细胞胰岛素抵抗中的作用。

Once activated,these two transcription factors translocate into the nucleus for inducing expression of INF-β,thus resulting in initiation of innate immune response and subsequent regulation of acquired immune response.

激活转录因子IRF-3和NF-κB，使其进入细胞核内，诱导干扰素的表达，从而启动固有免疫反应和调节随后的获得性免疫反应，增强机体抵抗病毒的能力。

XIAP expression could not be affected by the apoptotie inductions mediated by death receptor and mitochondria pathway in both cell lines.

通过对肾癌组织和细胞的研究，提示抗凋亡的XIAP在肾癌组织中呈肿瘤进展依赖性增高、在抗凋亡的肾癌细胞高表达，在肾癌细胞抗凋亡机制中发挥重要的作用，影响肾癌对凋亡信号的敏感性，使肾癌细胞获得生存发展的优势，从而促进肾癌的进展，并产生对诱导凋亡药物的抵抗；应用基因克隆和Tet-Off基因可控性表达系统技术构建的肾癌细胞XIAP稳定表达细胞系，对深入研究XIAP在肾癌抗凋亡中的机制，具有实用意义。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。