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However, when the cells were exposed to combined MF which superposes a noise MF over 50Hz MF with equal intensity, the receptor clustering induced by 50Hz MF were inhibited.

结果表明单独0.4mT噪声磁场不诱导细胞膜受体的聚簇;而等强度的噪声磁场与工频磁场相互叠加后,噪声磁场能干预50Hz工频磁场对细胞膜受体聚簇的诱导作用。

The models of the ear swilling of mice and paw edema of rats were adopted to assay anti-inflammatory effect. Results 5-ASA(ig,75,150 and 300 mg.kg-1,for 3 d)significantly reduced the ear swelling of mice and the paw edema of rats and also decreased the writhing. 5-ASA at the dose of 300 mg.kg-1 ig,prolonged pain latency on hot-plate reaction.

结果 5-ASA片剂3种剂量(75、150及300 mg.kg-1,ig×3 d)对二甲苯诱导的小鼠耳肿胀度及蛋清诱导的大鼠踝关节肿胀度均有明显抑制作用;以上剂量还可明显抑制小鼠扭体反应,大剂量还可延长小鼠热板的舔足反应潜伏期。

The resultant recombinant plasmid, terming pMB1, was transformed into E. coil BL21(DE3). IPTG was used to induce the expression of the target protein.

将重组质粒转化到宿主菌BL21 (DE3)中,对重组菌株BL21(pMB1)用IPTG进行诱导表达,并对最佳诱导时间进行了探索。

Result: Shengdi injection could depress the increasing of the amount of total white blood cells and neutrophils and inhibit the increasing of TNF-α, O-2, MPO caused by LPS, as well as relieve the pathologic change including Neutrophils infiltrating and mucous edema in tracheae after intravenous administration. While it did not show the effect on monocyte, and histological lesion of the lung tissue.

结果:生地注射液静脉给药可明显抑制LPS诱导的白细胞总数和中性粒细胞数目升高,对淋巴单核细胞数目无明显影响;明显抑制TNF-α,O-2,MPO水平升高;明显抑制LPS诱导的肺组织中性粒细胞浸润、气管黏膜水肿,对肺组织损伤无影响。

It uncouples oxidative phosphorylation but, unlike the aflatoxins, does not induce mitochondrial swelling or hinder Ca2+-induced swelling of mitochondria.

它解开氧化磷酸化但不像黄曲霉毒素类,不能诱导线粒体肿胀或阻止Ca2+诱导的线粒体肿胀。

The results show that, influenced by the rarefaction waves from the left sharp corner, the reaction zone is separated from the leading shock. Then, the detonation is degenerated into the deflagration. The winkled reaction front can be clearly identified in numerical schlieren and temperature contours.

结果表明:气相爆轰波在分叉管中传播,分叉口左尖点的稀疏波导致诱导激波后压力、温度急剧下降,诱导激波和化学反应区分离,爆轰波衰减为爆燃波。

Results:(1) The rats produced amphetamine CPP after treated with 2 mgkg^(-1) amphetamine for 4 days. Ketamine and low, middle, high dose rhynchophylline all could eliminate the CPP effect, and the effect of rhychophylline was increased in a dose-dependent manner. Rhychophylline itself could not induce CPP in normal rats.(2) When compared with normal rats, the NR2B expression in nucleus accubens and amygdaloid of the model rats was obviously increased. Ketamine and middle, high dose rhynchophylline could decrease NR2B expression induced by amphetamine, while low dose rhynchophylline did not affect NR2B expression. Rhynchophylline had no effect on RN2B expression in normal rats.

结果:(1)建立了苯丙胺(2mgkg^(-1),连续4d)诱导的位置偏爱模型,氯胺酮及钩藤碱低、中、高剂量均可消除苯丙胺诱导的位置偏爱效应,随钩藤碱剂量增加其效应加强,且本身无精神依赖性;(2)苯丙胺模型组大鼠伏核和杏仁核NR2B蛋白表达增加,氯胺酮及钩藤碱中、高剂量抑制NR2B表达,低剂量及本身对NR2B表达无影响。

At difierent time at ter inoculation with Fusarium oxysporum f.sp.cubenserace 4,the transcript pattems of WNB1 and WST3 was enhanced,which implied that the expression of WNB1 and WST3 may be related to the resistance of banana to Fusarium wilt.

用半定量PCR分析枯萎病菌诱导后野生蕉叶片中RGAs的表达情况,结果表明WNB1和WST3受枯萎病菌诱导后表达量增强,这表明WNB1和WST3的表达可能与香蕉枯萎病抗性相关。

A significant time-and-concentration-dependent inhibition of cell growth was found in all the cells treated with berbamine.

利用建立的人白血病裸鼠异种移植模型,在体外与体内研究小檗胺对多种类型白血病细胞的作用,明确小檗胺是否能诱导多种白血病细胞凋亡以及多种凋亡相关基因在其诱导细胞凋亡中的作用,为小檗胺有可能开发成为新型的抗白血病药物,并应用于临床治疗,提供实验和理论依据。

Based on the above findings, it could be concluded that:(1) berbamine could obviously inhibit the cell proliferation and induce apoptosis in four different kinds of leukemic cell lines (including K〓, Jurkat, NB〓, HL〓 cells) in a time-and-concentration-dependent manner in vitro.

综上所述,我们认为:(1)钙调素拮抗剂小檗胺在体外除对HL〓细胞外,还对其它3种不同类型的白血病细胞株(K〓、Jurkat、NB〓)细胞具有明显的增殖抑制作用及明确的诱导凋亡作用,并呈时间-浓度依赖关系,诱导细胞凋亡可能是其抑制白血病细胞增殖的主要方式之一。

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