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And we also research the impact of methylating on hydrogen bond and stacked bond in base pairs under considering water molecules.

研究结果表明,烷基化之所以能造成碱基错配是它可使碱基的质子迁移或烯醇互变现象容易发生,改变原有原子的电荷分布或配对模式,同时碱基自身的互变异构体会跟烷基作用,致使互变异构体能够稳定存在,影响正常碱基配对,引起碱基诱变,造成生理疾病的发生。

Cole must solve the enigma of Area 51 before the viral mutagen is released and irrevocably mutates all life on Earth.

科尔必须解决的谜区前51的病毒诱变发布和不可逆转地发生变异,地球上所有生命。

Taking Eremothecium ashbyii (abbreviated as Eaw95. 1) as the original strain, after Υ-ray mutation, tubercidin and 8--azaguaniae (8--AG) resistant tests, a strain labeled as T〓 capable of overproducing riboflavin was obtained and its genetic stability was analyzed. Compared with Eaw95. 1, the riboflavin productivity was improved about 40% by flask--shaking tests.

以Eremothecium ashbyii为出发菌(间称Eaw95.1),通过Υ-射线诱变,杀结核菌素和8-氮杂鸟嘌呤等结构类似物的的抗性筛选,获得了一株核黄素高产菌T〓,并对菌株的遗传稳定性进行了研究,获得了较好的效果,与出发菌株相比,核黄素的摇瓶发酵产量提高了近40%。

Guanosine overproducing mutant was derived from Bacillus subtilis T1001 by using ultraviolet and diethyl sulfate. The mutant was selected directionally and step wisely on the agar plates containing methionine sulfoxide and 8 azaguanine(8 AG).

以枯草芽孢杆菌T1 0 0 1为出发菌株,经紫外线、硫酸二乙酯逐级诱变处理,选育出腺嘌呤缺陷型菌株,然后经蛋氨酸亚砜、8 氮鸟嘌呤( 8 AG)结构类似物平板定向筛选,获得鸟苷高产菌株TA2 0 8。

The differences were significant in the indexes of eyes, lungs, thymuses, and adrenal glands between the genders.

目的:研究通过ENU诱变手段获得的遗传性角膜病小鼠B6-Co的生物学特性。

The doctoral dissertation focuses on secondary metabolitic material and biological characteristics of two species...

本文对粘帚霉属的两种药用植物内生真菌,进行化学成分和原生质体诱变育种两方面的研究。

In order to breed new germplasm for Narcissus tazetta,the bulb of Narcissus tazetta is used as explants.The adventitious buds is induced in MS media with hormone combination.γ-ray irradiation treatment of Narcissus tazetta combined with tissue culture is studied.Three materials,including the bulb basal plate tissues inoculated for 7 days,tissues transferred in fresh differentiation culture medium for three days after inoculated for 25 days,and small bulbs in vitro,are studied.

以带鳞片叶的鳞茎盘为外植体,接种在添加激素的MS培养基上,通过激素组合筛选合适的培养基获得不定芽,同时对在预分化培养基上接种7D的外植体、接种25D后转接到分化培养基上3D的外植体、诱导产生的试管小鳞茎进行辐照诱变处理,研究了60COΓ射线对中国水仙丛生芽分化以及小鳞茎生长的影响。

In cider to breed new gern1asm for Narcissus tazetta, the bulb of Narcissus tazetta is used as explants. The adventitious buds is induced in MS media with hormone combination.γ-ray irradiation treatment of Narcissus tazetta combined with tissue culture is studied. Three materials, including the bulb basal plate tissues inoculated for 7 days, tissues transferred in fresh differentiation culture medium for three days after inoculated for 25 days, and small bulbs in tarn, are studied.

以带鳞片叶的鳞茎盘为外植体,接种在添加激素的MS培养基上,通过激素组合筛选合适的培养基获得不定芽,同时对在预分化培养基上接种7d的外植体、接种25d后转接到分化培养基上3d的外植体、诱导产生的试管小鳞茎进行辐照诱变处理,研究了60Coγ射线对中国水仙丛生芽分化以及小鳞茎生长的影响。

The mutagenicity of seed powder and seed oil of transgenic CryIA cotton to mammals and fish was evaluated in this study. The raw cotton seed powder or seed oil was mixed into mice and fish's diet. Cyclophosphamide and NaF were used as positive controls respectively. Regular cotton seed powder and seed oil were used as negative controls. The micronucleus frequency in mice bone marrow polychromatic erythrocytes and in eripheral erythrocytes of Zebrafish were assayed in this study. The sperm malformation rate in mice was also investigated.

摘 要:分别以环磷酰胺和氟化钠作为阳性诱变剂,以普通棉的棉籽粉及棉籽油作为对照物,同时设阴性对照组,以成年封闭群昆明种雄性小鼠和斑马鱼为实验材料,将棉籽粉或棉籽油掺入饲料中饲喂小鼠或斑马鱼,检测小鼠骨髓嗜多染红细胞(Polychromatic erythrocytes, PCE)微核率(Micronucleus frequency, MN‰)和精子畸变率,以及斑马鱼外周血红细胞微核率。

The mutagenicity of seed powder and seed oil of transgenic CryIA cotton to mammals and fish was evaluated in this study. The raw cotton seed powder or seed oil was mixed into mice and fish's diet. Cyclophosphamide and NaF were used as positive controls respectively. Regular cotton seed powder and seed oil were used as negative controls. The micronucleus frequency in mice bone marrow polychromatic erythrocytes and in eripheral erythrocytes of Zebrafishwere assayed in this study. The sperm malformation rate in mice was also investigated.

分别以环磷酰胺和氟化钠作为阳性诱变剂,以普通棉的棉籽粉及棉籽油作为对照物,同时设阴性对照组,以成年封闭群昆明种雄性小鼠和斑马鱼为实验材料,将棉籽粉或棉籽油掺入饲料中饲喂小鼠或斑马鱼,检测小鼠骨髓嗜多染红细胞(Polychromatic erythrocytes, PCE)微核率(Micronucleus frequency,MN‰)和精子畸变率,以及斑马鱼外周血红细胞微核率。

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