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LTP in the hippocampal dentate gyrus was recorded as electrophysiologic index for evaluation of learning and memory.

目的 研究耳针对血管性痴呆大鼠学习记忆能力和海马齿状回长时程增强的影响。

Long-term potentiation is a model for research of learning and memory, it consideing the neural basis of memory formation.

长时程增强是研究学习记忆机制的一种模式,被认为是记忆形成的神经基础。

The study shows that the ability of resistance to deformation and the bending recoverability of SMPC materials are higher than that of SMP materials.

为了提高形状记忆聚合物的刚度性能,研制了纤维增强苯乙烯基形状记忆聚合物复合材料,对其动态力学和弯曲性能进行了测试分析,采用有限元分析法得到SMP和SMPC梁的弯曲变形规律,并利用经典层合板理论对其刚度进行分析。

Its main role, however, should not be as a reinforcer of memories, but as a tool to establish or re-establish memories in cases of poor recall.

它的主要作用,但是,不应该被视为一个记忆增强剂的,但作为一种工具来建立或重新建立召回记忆差案件。

With the deficit in the information processing on facial emotion perception of schizophrenic patients, the neurocognitive training program is based mainly on the Memory Processing Model, Treisman's Attenuation Model, signs of the eye movement, Ellis's Information Processing Model of Face Recognition, Zhuo's Morphological-Tuning Model, Wang's Two-Stage Face Recognition Model, and Anderson's Adaptive Control of Thought. The contents of the training contain self-instruction, feature abstraction, mnemonics, and positive reinforcement.

本研究以记忆历程模式为主轴,参考减弱模式的感官登录与减弱控制机转、眼球凝视现象、脸部辨识讯息历程模式、双阶段脸孔辨识模式的型态侦测模块、二阶段脸孔辨识模式的脸孔与表情表征、思考适应控制模式的陈述与程序知识等部分,并举证精神分裂病患在表情讯息处理历程各阶段-注意、编码、储存、提取的缺损现象,以自我引导、特征抽取、记忆增强、立即回馈等原则,设计神经认知行为取向的脸部表情辨认训练方案。

Results:Fractions extracted from Acorus tatarinowii Schott could enhance intelligence in multi-tests, inhibit AchE activity, and promote of c-jun gene.

结果 :石菖蒲提取物在多种实验中有改善学习记忆障碍的作用,并能降低乙酰胆碱酯酶活力,增强c -jun基因表达。

The mechanism may be related to reducing brain cholinesterase activity, inhibiting the accumulation of aluminium ions in brain, maintaining the normal level of Glu/GABA.Key words:Prepared Radix Rehmanniae; Learning and memorizing; Dysmnesia

结论熟地黄对于化学药品所致记忆障碍模型小鼠具有增强其学习记忆和空间记忆能力的作用,其作用机制可能与改善中枢胆碱能神经系统功能,降低脑内Al3 含量,保护脑组织及维持脑内Glu/GABA的正常水平有关。

So GSL in combination with choline can synergically reduce the impairment of learning and memory of AD model rats and the mechanism may be involved in enhancing the function of central cholinergic system.

表明 GSL和胆碱合用有协同改善AD模型大鼠学习记忆障碍的作用,其机理与协同提高ChAT活性,增强中枢胆碱能神经功能有关。

These results suggest that morphine withdrawal selectively impairs the cued fear extinction through inhibiting the ERK phosphorylation in the amygdale and mPFC. Histamine deficiency not only enhances acquisition the cued and contextual fear conditioning and but also potentiates the impairment of extinction of cued fear memory.

这些结果提示:吗啡戒断能选择性抑制恐惧记忆的消除,此作用是通过抑制杏仁核和mPFC脑区内ERK蛋白磷酸化来实现的;组胺缺乏能增强线索和背景恐惧记忆的获得以及增强吗啡戒断对线索恐惧记忆消除的抑制作用。

Histamine deficiency markedly potentiated the acquisition of learning in cued and contextual fear conditioning in the HDCKO mice,but had no effect on cued and contextual fear extinction.However,histamine deficiency potentiated the inhibitory role of morphine withdrawal in cued fear extinction.Consistent with the behavioral results,morphine withdrawal decreased ERK phosphorylation in the amygdala and mPFC but not in the hippocampus of WT and HDCKO mice,and ERK might not be phosphorylad in the amygdale and mPFC of HDCKO mice after the 4th training of cued fear extinction.

但HDCKO小鼠增强了吗啡戒断对线索恐惧记忆消除的抑制作用,与行为学实验结果相一致是,,吗啡戒断能明显降低WT和HDCKO小鼠在线索恐惧记忆消除第4次训练后杏仁核和mPFC脑区的ERK磷酸化水平,但对海马脑区的ERK磷酸化没有作用;HDCKO小鼠在线索恐惧记忆消除训练的第4次训练后杏仁核、mPFC脑区的ERK蛋白没有明显磷酸化激活。

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