记忆

Results Both of MED and optimized MED improved the memory results about latent time and error frequency of dysmnesia mouse models significantly comparing with model control group (P nbsp; 0.01), and the improvement of optimized MED was more noticeable than that of MED (P nbsp; 0.01). Comparing with control group, optimized MED up-regulated the expression of CREB gene significantly (P nbsp; 0.01), and the effect had a dose response relationship.

结果：强记汤及天然脑活素水煎液对动物记忆障碍模型小鼠记忆成绩中的潜伏时间、错误次数与模型对照组比较均有统计学意义（P 0.01）；而且天然脑活素的改善效果明显优于原方（P 0.01）；不同剂量天然脑活素水煎液 CREB 表达水平与对照组比较有统计学意义（P 0.01），且有剂量反应关系。

MethodsThe behavior changes of learning and memory disorder induced by dysmnesia were observed on mice, related indexes were detected as well.Mice were divided into five groups randomly:normal group, control group, piracetam group, prepared Radix Rehmanniae high-dose group, PRR low-dose group.

方法对化学药品所致记忆障碍模型小鼠进行学习记忆行为实验并检测相关指标，实验动物随机分为5组，分别为：正常对照组、模型组、脑复康组(500 mg/kg)、熟地高剂量组(9 g/kg)、熟地低剂量组(4.5 g/kg)。

Methods the spf mice were treated with med or optimized med in dose of 29.3 g/kg and 18.6 g/kg per day respectively by intragastric administration for five days continuously. and then, the various dysmnesia mouse models were prepared respectively with scopolamine (3 mg/kg), cycloheximide (120 mg/kg) by intraperitoneal injection and 40% alcohol (0.1 ml/10 g body weight) by intrag astric administration on the sixth day.

将强记汤及天然脑活素分别以 29.3 g/kg和 18.6 g/kg 的量每日经口灌胃给予 spf 级小鼠，连续 5 d，第 6 天给药 1 h 后制备成记忆障碍模型，第 7 天给药 0.5~1 h 后分别用跳台法和避暗法测试记忆成绩；另用不同剂量（50 g/ml 和 150 g/ml）天然脑活素水煎液处理大鼠大脑 b104 cns 神经细胞，以荧光素酶方法检测 creb 表达水平。

Objective:to compare the effects between seed stem and commercial rhizoma gastrodia on memory dysmnesia induced by scopolamine in rat .methods: a month before the scopolamine administration, seed stem and commercial rhizoma gastrodia were given to two groups of young rats with scopolamine–induced dysmnesia model, incubation period of findingplatform were measured by means of morris watter-maze.

目的比较天麻种麻与天麻商品麻改善东莨菪碱诱发的记忆障碍的疗效。方法用天麻种麻，商品麻灌胃饲养幼鼠一个月，然后用东莨菪碱诱发大鼠造记忆获得性障碍模型，通过morris水迷宫测试大鼠寻找平台的潜伏期。

Methods The SPF mice were treated with MED or optimized MED in dose of 29.3 g/kg and 18.6 g/kg per day respectively by intragastric administration for five days continuously. And then, the various dysmnesia mouse models were prepared respectively with Scopolamine (3 mg/kg), Cycloheximide (120 mg/kg) by intraperitoneal injection and 40% alcohol (0.1 mL/10 g body weight) by intrag astric administration on the sixth day. Next day, memory result was estimated by using Step-down Test and Dark-avoiding Test after the mice were administered for half or an hour.

将强记汤及天然脑活素分别以 29.3 g/kg和 18.6 g/kg 的量每日经口灌胃给予 SPF 级小鼠，连续 5 d，第 6 天给药 1 h 后制备成记忆障碍模型，第 7 天给药 0.5~1 h 后分别用跳台法和避暗法测试记忆成绩；另用不同剂量（50 g/mL 和 150 g/mL）天然脑活素水煎液处理大鼠大脑 B104 CNS 神经细胞，以荧光素酶方法检测 CREB 表达水平。

Objective To explore into the probable mechanism of Alzheimer's diseaseby the acupuncture treatment combined with DGSYS of TCM.Methods Three kinds of model rats with dysmnesia which were made by injected into drug of scopolamine or NaNo 2 in the abdomen separately and injured at the hippocampal CA 1 in brian by drug of quinolinic acid treated by single acupuncture or acupuncture combined with DGSYS of TCM or DGSYS of TCM were observed separately,to compare different influence on dysfunctions of acuquisition and consoli-dation of memory induced by drugs and injure with nimodipineor the normal rats.

通过腹腔注射药物东莨菪碱或亚硝酸钠，或者用奎宁酸损毁大脑海马CA 1 区诱发大鼠发生记忆力障碍，造成不同类型的大鼠&痴呆&模型，对照性观察针刺、针刺加DGSYS、DGSYS及NM对记忆障碍功能的影响和与记忆相关实验指标参数的变化。

Li Zhongren,Shen Meihong,Mu Yanyun,et al.Nanjing University of TCM,Jiangsu210029. Objective To explore into the probable mechanism of Alzheimer's diseaseby the acupuncture treatment combined with DGSYS of TCM.Methods Three kinds of model rats with dysmnesia which were made by injected into drug of scopolamine or NaNo 2 in the abdomen separately and injured at the hippocampal CA 1 in brian by drug of quinolinic acid treated by single acupuncture or acupuncture combined with DGSYS of TCM or DGSYS of TCM were observed separately,to compare different influence on dysfunctions of acuquisition and consoli-dation of memory induced by drugs and injure with nimodipineor the normal rats.

目的 探索临床针刺加当归芍药散治疗阿尔采默氏症的可能机理方法通过腹腔注射药物东莨菪碱或亚硝酸钠，或者用奎宁酸损毁脑海马CA 1 区诱发大鼠发生记忆力障碍，造成不同类型的大鼠&痴呆&模型，对照性观察针刺、针刺加DGSYS、DGSYS及NM对记忆障碍功能的影响和与记忆相关实验指标参的变化。

The hippocampus is the most important encephalic region relative to function of learning and memory.

海马是学习和记忆的关键脑区，海马长时程增强(long-term potentiation，LTP)是NMDA受体依赖性突触传递效能的持续性增强，是脑学习和记忆功能在突触水平的研究模型和细胞基础。

Nickel-titanium shape memory alloy composed of near equiatomic components of nickel and titanium is cha...

由近等原子比组成的NiTi形状记忆合金具有独特的性能：形状记忆效应和超弹性。

Howerer, the aim at the recover from the memory obstacle methods are lack. The errorless learning among them is an effective rehabilitation training path.

而针对记忆障碍的康复方法尚不多，其中无错性学习是一种有效的记忆康复训练方法。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。