言语失调

Clinical features were characterised by allolalia, dramatically indifference emotion,left agraphia , left ideomotor apraxia, alien hand syndrome, hemispatial neglect , gait apraxia, sensation and motion abnormality.

胼胝体病变的临床表现较复杂，10例患者分别表现有言语障碍、情感淡漠、左手失写、左手运动性失用、陌生手综合症、半侧空间忽略、步态失调、感觉和运动异常等。

CB showed spastic-ataxic dysarthria at her first evaluation, yet had gradually transformed to ataxic-spastic dysarthria in during two years.

个案研究显示，CB呈现与文献相当一致的言语表现，为运动失调-痉挛型两种呐吃之混合型，在两年间二者的比重虽有所变化，仍以运动失调与痉挛型为主要特徵。

Turned out to be spasmodic dysphonia, a rare and mysterious voice disorder that leaves the voice cutting in and out like a faulty PA system.

结果诊断是：间歇性言语障碍。这是一种极其罕见，难以解释清楚的嗓音失调病症。这种病使你说话时声音结结巴巴的，像个有故障的公共演讲装置。

Child cerebral form is the most common form of ALD.Its main clinical characteristics are mental impairment,limbs weakness,alalia,ataxia,seizures,viral and auditive disturbances.Some patients accompanied by visaul nerve atrophy,adrenal cortex and testicle impairment.ALD can be diagnosed by clinical characteristics combined with cerebral MRI.

结论ALD以儿童脑型常见，主要表现为智能下降、肢体无力、言语不清、共济失调、视听力下降及癫发作等症状，可伴有视神经萎缩、肾上腺皮质及睾丸损害，依据临床症状和典型的MRI表现可以进行临床诊断。

The age of onset were 7 to 11 years old.Three patients revealed mental impairment and limbs weakness.Other symptoms included alalia,ataxia in three cases and visual and auditive disturbances in 2 case,One case had visual nerve atrophy and seizures.Testost in one case and 17-hydroxide steroid in another case were degressive.Cerebral biopsy in one case suggest lipide sediment.Testicle impairment in one case was found by ultrasonography.The cerebral magnetic resonance imaging of all the 4 patients showed the characteristic pattern of symmetrical long T1 and long T2 signal in the parieto-occipital region.

结果发病年龄7~11岁，均有智能下降、肢体无力，3例伴言语不清、共济失调，2例伴视听力下降，1例伴视神经萎缩、癫发作，血睾酮降低及血17-羟类固醇降低各1例，B超示双侧睾丸弥漫性病变、脑活检示类脂质沉积病各1例，4例磁共振均见双侧枕顶叶对称性蝶翼状长T1、长T2信号灶，可累及颞叶、内囊和脑干白质。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。