触地

And I saw him come close unto the ram, and he was moved with choler against him, and stroke the ram, and brake his two horns: and there was no power in the ram to stand before him, but he cast him down to the ground, and stamped upon him: and there was none that could deliver the ram out of his hand.

007 我见公山羊就近公绵羊，向他发烈怒，牴触他，折断他的两角。绵羊在他面前站立不住；他将绵羊触倒在地，用脚践踏，没有能救绵羊脱离他手的。

She liked handling him. She loved having his body in her charge, absolutely, to the last menial offices. She said to Connie one day: 'All men are babies, when you come to the bottom of them. Why, I've handled some of the toughest customers as ever went down Tevershall pit. But let anything ail them so that you have to do for them, and they're babies, just big babies.

她是很伶俐的，她的抚触是温柔的，缠绵的，而又有点迂缓的，起初，她的手指在他的脸上的这种无限的温柔的抚触，渐渐地她的手指尖熟悉了克利福的脸颊和嘴唇，下含和颈项了，他是个养尊处优的人，他的脸孔和咆部是够好看的，而且他是一位贵绅。

Propofol induced Cl- currents at concentrations of 10-5 and10-4 M, which were sensitive to picrotoxin and, to a lesserextent, to strychnine. Propofol (10-6 M) enhanced -aminobutyricacidA (GABAA; 10-6 M)-induced current synergistically. Moreover,propofol (10-5 and 10-4 M) significantly increased the decaytime of evoked-inhibitory postsynaptic currents, which suggestsa postsynaptic modulation of GABAA receptors.

异丙酚在浓度10-5~10-4M 时，産生 Cl-电流，对印防己毒素敏感，在更小浓度范围内，对番木鼈碱敏感。10-6M 的异丙酚加强 GABAA 産生的电流，另外，异丙酚（10-5、10-4M ）显著地增加了突触后诱发-抑制电流的衰退时间，提示了 GABAA 受体的突触后调节作用。

Flies increase sleep both after exposure to an enriched social environment and after protocols that induce long-term memory. We found that flies mutant for rutabaga, period, and blistered were deficient for experience-dependent increases in sleep.

研究人员称，神经学家们认为，形成新的神经元突触是大脑进行记忆和学习的一种重要途径，但由于头颅空间有限等原因，大脑不能无限制地增加神经元突触。

Sperry showed that the regenerated retinal axons always innervated the original sites of termination in the optic tectum. This experiment strongly disprove the resonance hypotheses proposed by Paul Weiss, who suggested that the nerve growth and synapse formation are largely random events, and the precision of connections between nerve cells emerged by selectively eliminating the inappropriate connections, only at later developmental stage.

Sperry的实验在支持Cajal假说的基础上，进一步明确发育过程中轴突的生长及突触的形成具有内在决定性，并且有力地反驳了当时占主流地位的由Paul Weiss于1930～40年代提出的resonance hypothesis，后者认为轴突的生长和突触的形成大多是一些随机事件，成年脑中的精确联系是通过对随机形成的不恰当联系进行选择地消除形成的。

Especially, the number of type Ⅰ complex terminals which come from unmyelinated afferent fibers recovered to the level of unoperated side. It indicates that morphine may promote the collateral sprouting and synaptic reinnervation of primary afferent fiber, unmyelinated afferent in particular. 4. Although the collateral sprouting and synaptic reinnervation were shown also in spinal cord of operated side in 34 days spared root rats, they were slower than that of morphine spared root group.

表明吗啡促进了备用根初级传入纤维，特别是无髓纤维更快地向L〓脊髓段侧支出芽，稍后在L〓平面脊髓内侧支出芽以及突触重建。4、34天备用根大鼠术侧脊髓内也有侧支出芽和突触重建，不过侧支出芽的速度要比吗啡组慢。5、电镜定量结果也显示，吗啡备用根大鼠和备用根大鼠术侧备用根的无髓纤维数比备用根大鼠非手术侧的分别增多60％和42％。

PubMed abstract: To examine the relationship between synaptic plasticity and learning and memory as directly as possible, we have developed a new simplified preparation for studying the siphon-withdrawal reflex of Aplysia in which it is relatively easy to record synaptic connections between individual identified neurons during simple forms of learning.

PubMed摘要：为了尽量直接地研究突触可塑性与学习和记忆的联系，我们做了新的一个简化制备，目的是研究海兔缩虹吸反射，其中较容易在学习的简单形式中，记录个体确定之神经元的突触联系。

The in vitro effects of Gln49-PLA_2 were examined using the chick biventer cervicis nerve muscle preparation. Gln49-PLA_2 caused a dosedependent blockade of neuromuscular transmission. The time required to cause 50% blockade was about 150 min at the highest concentration 100μg/ml. This inhibition appeared to be presynaptic in origin as evidenced by the lack of effect of toxin on responses to exogenous acetylcholine in the non-stimulated BCp.

Gln49-PLA_2能够剂量依赖性地抑制颈二腹肌神经信号正常传导并影响肌肉收缩，在100μg/ml剂量下，肌肉收缩幅度在150分钟后达到50%的抑制率；同时，随着Gln49-PLA_2浓度的降低，肌肉收缩幅度的抑制效率也逐渐降低；实验证明Gln49-PLA_2对突触后膜乙酰胆碱受体敏感性无影响，对神经肌肉信号传导收缩的抑制作用位点在突触前膜。

In the presence of L-isoproterenol (through local infusion into area CA1), the theta-pulse stimulation with the parameter of 10 Hz, 150 pulses/train, 1 train, a frequency weakly modifying synaptic strength, induced a robust LTP, and this effect was blocked when DL-propranolol was co-administered. By contrast, the theta-pulse stimulation with the parameter of 5 Hz, 150 pulses/train, 3 train, a frequency strongly modifying synaptic strength, induced a significantly smaller LTP when DL-propranolol was administered into area CA1. Accordingly, DL-propranolol impaired rat's spatial learning in the water maze when infused into area CA1 20min pretraining.

正常情况下对突触传递效能仅有微小调制作用的10Hz的θ节律刺激（每串150个脉冲，1串），在CA1区局部给予L-异丙肾上腺素后，显著地诱导出LTP，这一效应可被DL-心得安所阻断；相反，正常情况下对突触传递强度有显著调制作用的5Hz的θ节律刺激（每串150个脉冲，3串），在CA1区局部给予DL-心得安后，所诱导出的LTP被显著压抑。

I have therefore generated several p130cas RNA interference transgenic lines to determine the possible function of p130cas during neurogenesis. Knockdown of p130cas expression in developing neurons resulted in partial fusion in the commissures axon fascicles of CNS, photoreceptor axon targeting and guidance defects, and bulged synapse boutons at the neuromuscular junction. Moreover, reduced expression of p130cas in sensory organ precursor cells and proneural clusters resulted in bristle development defects.

为了了解p130cas的功能以及更进一步的分析p130cas在神经发育过程所扮演的角色，我建立一系列可以执行RNA干扰技术的转殖果蝇，结果显示在果蝇的神经中降低p130cas的表现会造成腹部神经索中原来排列整齐的commissure axons神经束偶尔会出现不正常的融合；若将p130cas专一地在果蝇眼睛中降低则会造成果蝇视神经突触目标辨识与突触导向的缺陷；而如果局部的运动神经系统中降低p130cas的表现会造成在神经肌肉接点的神经突触有澎大的现象；此外在果蝇的感觉器官前细胞以及原神经细胞丛，降低p130cas的表现则会导致刚毛发育的缺陷。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。