角质化

During the process of long-time adaptive evolution, wetland plants adopted a series of special strategies to acclimate to salt stress. The main strategies are: 1 life history adjustment, e. g., to adjust seed germination time, implement seed dormancy and viviparity, and change reproductive manner to escape from direct salt stress, 2 morphological adjustment, e. g., to adjust biomass allocation pattern, age stem, defoliate, and carnify vegetative organs to isolate the redundant Na(superscript +) to the inactive-metabolism shoots or exclude the Na(superscript +)from tissues; 3 anatomic adjustment, e. g., to sink stoma, develop aerenchyma, and thicken cuticle and phellogen to maintain normal photosynthesis and respiration; 4 physiological and biochemical adjustment, e. g., to exclude and excrete salt, compartmentalize ions, adjust osmosis, do selective absorption, regulate hormones, and induce antioxidative enzymes to maintain the osmotic equilibrium and eliminate the active oxygen in cell; and 5 molecular level adjustment, e. g., to start up many salt-induced genes to regulate the metabolic responses to salt stress.

在长期的适应进化过程中，湿地植物形成了多种适应盐胁迫的策略，主要有：1生活史方面，植物可通过种子萌发时间的调整、种子体眠、胎生、繁殖方式的改变等逃避盐度的直接伤害；2形态学方面，植物可通过生物量分配模式的调整、茎的老化、落叶及营养器官的肉质化等将多余的Na隔离到代谢不活跃的茎中或将其排出体外；3解剖学方面，植物可通过气孔下陷、发达的通气组织、增加细胞木栓层、角质层及栅栏组织的厚度等以维持植物正常的光合作用和呼吸作用；4生理生化方面，植物可通过离子区隔化、拒盐、泌盐、选择性吸收、渗透调节、激素调节及抗氧化物酶的诱导等来维持细胞内正常的渗透压，清除胞内活性氧分子；5分子水平方面，植物可通过多种与盐胁迫相关的基因来调控细胞内的多种代谢反应。

Methods: Density gradient centrifugalization and absorption technique wererespectively applied to detach peripheral blood mononuclear cells andperipheral blood lymphocytes,T lymphocytes were got by Nylon postabsorption method, and CD4+T and CD8+T lymphocytes divided with anti- CD4 andanti-CD8 antibody by alexin cytotoxic method.

密度梯度离心法分离外周血单个核细胞，玻璃器皿吸附法分离外周血淋巴细胞，尼龙棉柱法分离 T 淋巴细胞，补体介导的细胞毒法分别制备 CD4+T和 CD8+T 淋巴细胞，采用 T 淋巴细胞与角质形成细胞共培养技术研究银屑病患者外周血 T 细胞对角质形成细胞的影响，免疫组化法检测共培养角质形成细胞 Ki67、c-Myc 及 Bcl-xL 蛋白的表达。

Our skin every day on their own metabolism, resulting from the basal cells gradually reach the skin surface, and then become a cuticle, the skin hyperkeratosis cycle is usually around 28 days, due to the environment, season, UV, rest is not normal and other factors, sometimes cause slow metabolism, so our skin piles up thicker stratum corneum, horny excessive accumulation, it will allow a transparent discussion so that the skin does not feel a sense of, and have lost the flexibility of the original, so fixed and the appropriate exfoliation, dander can be removed, so that the skin is more translucent.

我们的肌肤每天都会自行新陈代谢，由基底层产生的细胞会慢慢的到达肌肤的表面，然后成为角质层，皮肤的角化周期通常约为28天，由于环境、季节、紫外线、作息不正常等因素，有时会使新陈代谢变得缓慢，所以我们的皮肤表面角质层越堆越厚，角质过度的堆积，就会容议让肌肤感觉没有透明感，也失去原本的弹性，所以固定且适当的去角质，可以将皮屑去除，让肌肤更晶莹剔透。

Porokeratosis is a keratinization disorder characterized by multiple small lesions with an elevated thick keratotic border and central atrophy.

汗管角化症是一种少见的慢性角化性皮肤病，以中央轻度萎缩边缘堤状角质嵴围绕的皮损为特征。

Horny layer is the outmost layer of epidermis, its thickness is decided by different parts of human body, it's about 0.02mm at the thinnest parts, and 0.5mm at the thickest. It is made up of 5-10 layers of enucleated cornified cells that contains keratin and horny fat, which has the capability of resisting weak acids and weak bases , they array closely and become a natural barrier to moisture content and some chemical substances, so as to prevent the water logging of bodily fluids and endosmose of chemical substances.

角质层是表皮的最外层，其厚度依身体部位的不同而定，最薄处约0.02mm，最厚处约0.5mm由5-10层含有角蛋白和角质脂肪的无核角化细胞组成，角质层细胞有抵抗弱酸弱碱的能力，角质层细胞排列紧密，对水分及一些化学物质有天然屏障作用，因而可以阻止体内液体的水渗和化学物质的内渗。

Stratum granulosum: outside the Spinous layer, made up of cells further differentiated to cuticle cells, so it would lose the nucleolus and turn to the enucleated startum lucidum and horny layer after completely cornified to horny layer.

颗粒层：位于棘层之外，是进一步向角质层细胞分化的细胞，因此它起着向角质层完全角化后，便失去细胞核，而转化成无核的透明层和角质层。

Thus, in the process of chronic eczematous dermatitis, the apoptosis of keratinocyte is not only a turning point, but also a new target of drug screening.

因此，角质形成细胞的凋亡为湿疹性皮炎慢性化的转折点，阻断角质形成细胞的凋亡可以减轻湿疹慢性化进程的发生，从而为湿疹性皮炎的治疗提供了一条新的途径，成为药物筛选的一个新靶点。

Based upon the ecoanatomical method, leaf anatomical characters of eleven populations of six evergreen species (Cyclobalanopsis glauca, C. myrsinaefolia, C. gracilis, Castanopsis sclerophylla, C. eyrei and Lithocarpus glaber) from the eastern subtropical area of China were analyzed and compared with SPSS, DCA and TWINSPAN. The results are: 1. Although the leaf structures of the eleven populations still belong to the mesophyll type, they all express the trend of xerophilization. 2. There are some differences in leaf anatomical characters among populations, species and genera, which occur as the results of their adaptation to different habitats. 3. Different leaf anatomical characters have different variations among populations, species and genera, of which leaf thickness and palisade tissue thickness (considered as ecological adaptation characters) have greater variation than sponge tissue thickness, lower cuticle thickness and lower epidermis thickness (as systematical evolution characters). 4. The leaves of C. sclerophylla and C. glauca with thicker lamina, palisade tissue and cuticle (a multilayered upper epidermis in C. sclerophylla) are thought to better adapt to their dry habitat. The leaves of C. eyrei with thicker sponge tissue, although characterized by a multlayered upper epidermis, adapt to their humid and warm habitat. The leaves of C. myrsinaefolia and C. gracilis characterized by a thinner lamina, a less palisade tissue and a moderate cuticle thickness adapt to the humid and cool habitat in a middle mountain.

选取亚热带东部替代分布明显的壳斗科6种常绿树种（青冈、小叶青冈、细叶青冈、苦槠、甜槠和石栎）的11个种群叶片进行生态解剖，并用SPSS， DCA和TWINSPAN比较分析，结果表明：①尽管6种11个种群叶的结构仍属中生叶型，但有着不同程度的趋旱适应；②叶的解剖性状在属间、种间和种群间均存在着不同程度的差异，这是它们适应各自生境的结果，青冈和石栎的种内差异较大，反映出它们对环境变化有较强响应能力；③叶片的不同解剖性状在属、种类和种群间的变化并不同步，其中叶片和栅栏组织厚度等性状差异突出，反映它们更易受环境的饰变，是生态适应性状，而海绵组织、下角质膜，特别是下表皮厚度等性状差异较小，显示出这些性状的稳定性，可以认为是系统演化性状；④苦槠、青冈具有较厚的叶片、栅栏组织、角质膜和发达输导和机械组织，苦槠还具有复表皮，表现出对旱化生境的适应；甜槠尽管具有复表皮和较厚的叶片，但这是海绵组织增厚的结果，是对中生生境的适应；小叶青冈和细叶青冈具有较薄的叶片和栅栏组织、角质膜厚度居中等特点，可能是对中山凉湿生境的适应。

Skin keratinocytes and epithelial cells from hair follicle organized into epidermoid cyst-like spheroids when cultured on nubby dermal papilla cells gel and epidermoid layer-like structure was formed when they were cultured on free dermal papilla cells and skin fibroblasts gel.

团块状的毛乳头细胞诱导毛囊上皮细胞和皮肤角质形成细胞形成球形结构；而游离分散的毛乳头细胞和皮肤成纤维细胞诱导毛囊上皮细胞和皮肤角质形成细胞形成表皮样层化结构。

Histologically, the tumor showed a wide branching cavity lined by keratinizing epithelium connected to the surface. There were keratin, corneocytes and hair shafts in the dilated cavity.

组织学下此肿瘤中心为一连接到表皮的分枝状空腔，为角化上皮所覆盖；空腔内有角质，角质细胞及毛发。

The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作：对伸臂位于顶部的单层框架—筒体模型进行分析，提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。