角质

However compared with the Euramerican Flora, the research work on cordaitean cuticles from the Cathaysian Flora in China is much more insufficient.

中国华夏植物区科达植物的研究历史虽然最早可上溯至1883年，但直到1991年才首次报道其角质层构造。

Lamellar granules function in this space, primarily at the interface between the granular and cornified cell layers.

间隙主要是在颗粒层和角质层细胞的交界处，薄层状颗粒在此间隙发挥作用。

Epidermis- the outermost layer: dead cornified cells, continuously loss to protect the underlying tissue.

在最外层的是众多层已死的角质化的细胞，它们不断脱落以保护下面的组织。

PAI-3 was expressed in the human skin and mainly located in the superficial,more differentiatied layers of the epidermis,and was incorporated into the cornified envelope of terminally differentiated keratiocytes.

1、PAI-3 在人皮肤表皮组织中表达，且主要位于分化程度较高的表皮KC 中，其存在终末分化KCs 角质壳中。

PAI-3 was incorporated into the cornified envelope of terminally differentiated keratiocytes.

PAI-3 存在终末分化KCs 角质壳中。

At each age stage , Skin appears over - cornified cuticle , disappeared hair shaft and abnormal hair bulb and hair follide that filled with some cornified substances , but the dermis varied.

各年龄段无毛小鼠表皮均有一层角化过度的角质层，毛干消失，毛球结构不正常，毛囊被一些角化物质充填。

PAI-3 expression increased in the processes ofKCs differentiation. PAI-3 can incorporate into the cornified envelope andmay promote the differentiation ofkeratinocytes.

人表皮KC分化过程中， PAI-3的表达随着分化的增加而增加， PAI-3存在终末分化KCs角质壳蛋白中，表明PAI-3参与KC分化的作用。

2The involvement of MFT in woman is more than that in man.(3)The patients showed multiple dome-shaped, skin-colored, firm papules on the face. Some patients also present the lesions on the scalp and neck. No lesion showed the malignant tendency.(4) The histologic findings of MFT are cornified cysts and some nests of basaloid epithelial cells.(5)There were variable clinical expressions in different patients of the same family.(6) Some pedigrees were also affected by feckle or symmetrical progressive erythrokeratoderma, which were not found in MFT patients of other origin.

MFT临床分析总结：①MFT遗传方式为常染色体显性遗传；②女性发病多于男性；③中国汉族人MFT的典型皮损特征为面部乳白色半球形或圆锥形丘疹，质地坚实，只有2个家系皮损分别发生于头皮及颈部，均无恶化倾向；④组织病理特征为角质囊肿和由基底样瘤细胞构成的肿瘤岛；④同一家系中不同的患者表现度不同；⑤个别家系可伴发雀斑及进行性对称性红斑角化症，其它家系不伴发其他疾病。

An amount increase ofPAI-3 andK10 was observed after theKCswere cultured for48 h in high calcium medium,butat72 h the exprssion ofPAI-3 decreased. The positive stain ofPAI-3 wasmainly localized in perinuclearmembrane in lowcalcium medium and in cytoplasm in high calcium medium. PAI-3 was incorporated into cornified envelope ofterminally differentiated keratinocytes.

结果 高Ca2+浓度下培养24 h后，分化标记物K10弱阳性表达， PAI-3呈阳性表达；培养48 h后， K10强阳性表达，而PAI-3的阳性表达明显增加， 72 h后，表达开始降低，在低Ca2+浓度下阳性染色主要位于细胞核膜周围而高Ca2+浓度下主要位于细胞质，同时， PAI-3存在终末分化KCs角质壳中。

At the same time, they increased their cuticular surface hydrocarbons.

在此同时，他们增加了其表面角质层的碳氢化合物。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。