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Thus.how to prevent and treat corneal graft rejective reaction and Corneal neovascularization is the emphasis in the research area of corneal disease.

因此,如何防治角膜移植术后排斥反应及新生血管一直是角膜病研究领域的重点和难点。

It is currently accepted that corneal graft rejective reaction is a complicate reaction course which is led by T lymphocyte,the over-activation of cytokine and adherence factor participate corneal graft rejective reaction.

目前研究表明,角膜移植排斥反应是一个T淋巴细胞主导参与的复杂的反应过程,受多种因素的调节,许多细胞因子、粘附因子的过度活化参与角膜移植排斥反应。

METHODS: Porcine cornea stromata were processed by serial digestion of trypsin, DNase and RNase, and then were implanted into corneal stroma layer of New Zealand rabbits.

将用去垢剂联合酶的方法脱细胞处理的猪角膜基质材料植入兔角膜基质囊袋中,进行裂隙灯观察并照相。

P<0.01. 28d, q=4. 0452, p<0.05 . Corresponding pathologic result shows that the corneal stromal of height edema increase thickness to have infiltration of inflammation cells with hyperplasia of fibroblast cell and large vessel. The collagen fiber in stromatic layer is dissolved and destroyed seriously, suggesting that in addition to HSV-1's direct destructuring effect, inflammatory cells that might play an important role in the pathology of HSK induce the immune-pathological reaction.

相应的组织病理学研究结果显示(UV-B 14天):病毒对照组角膜基质层高度水肿、增厚,并有大量中性粒细胞等炎性细胞浸润、成纤维细胞和新生血管增生,胶原纤维肿胀、分解等,说明除HSV-1对角膜组织直接破坏外,炎性细胞介导的免疫病理反应在复发性HSK发病机理是重要的因素。

After observing the specimens from JMA-m groups, we have found that epithelium and endothelium of cornea full, the lesion are light edema at stromatic layer. One small amount of inflammatory-cell infiltrate presents the collagen fiber lack of rules at shallow stromatic layer.

观察角膜安的结果表明,中药中剂量组角膜上皮和内皮层完整,基质轻度水肿,浅基质层内少量炎性细胞浸润,胶原纤维走行欠规则,整体改变较低剂量组减轻。

Corneas and subbasal nerve fibers were examined by confocal microscopy at 1 day, 1 week, 1 month, 3 months and 6 months after the operation.

手术患者分别在术后1d、1周、1个月、3个月、6个月时行角膜共焦显微镜检查,比较两组患者术后角膜上皮下神经纤维再生的情况。

METHODS: Regeneration of the corneal subbasal nerve plexus after epithelial debridement was measured.

测量角膜上皮刮除术后角膜基底下神经丛的的再生。

Between LASIK and BSL,But there were not significantly different in length and morphology of corneal subbasal NFBs between LASIK and BSL at every time point of post-operation.

虽然在等效球镜度、术前及术后角膜厚度、手术切削深度等方面,LASIK与BSL两组存在显著性差异,但LASIK组与BSL组术后角膜上皮下神经纤维再生长度和形态学在各时间点无明显差异。

There were significant differences between LASIK and BSL before and after the operation when mean refraction, corneal thickness, ablation depth, etc., were compared. But there were no significant differences in the length and morphology of corneal subbasal NFBs between two groups at every postoperative time point.

虽然在等效球镜度、术前及术后角膜厚度、手术切削深度等方面,两组之间差异存在统计学意义,但LASIK组与BSL组术后角膜上皮下神经纤维再生长度和形态学在各时间点差异无统计学意义。

Objective To explore factors which lead to occurrence of subepithelial corneal haze after laser subepithelial keratomileusis.

目的 探讨准分子激光上皮下角膜磨镶手术后角膜上皮下雾状混浊发生的相关因素。

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