角膜

One hundred seventy-seven eyes of 161 patients consecutive who had corneal edema resulting from Fuchs endothelial dystrophy, pseudophakic bullous keratopathy, aphakic bullous keratopathy, failed graft or iridocorneal endothelial syndrome.

连续的161位患者的177只眼，都有角膜水肿。病因分别为FUCHS角膜内皮营养不良，人工晶体眼大泡性角膜病变，无晶体眼大泡性角膜病变，移植术失败和虹膜角膜内皮综合征。

Abnormal expression of type Ⅰ～Ⅵ could be found in the onset of illness. The decreasing of collagen could causes the weaken of the stability of stroma lamellar and the cornea shap to conus. The onset of keratoconus is related to collagen

胶原Ⅰ～Ⅵ型的表达在圆锥角膜的发病过程中有明显的变化，胶原成分的减少会导致角膜的机械抵抗力减弱，并使角膜前凸变薄，最终影响角膜的正常形态，圆锥角膜的发病与胶原密切相关。

After 1-month treatment, his best corrected visual acuity improved from 0.05 initially to 1.2, and the corneal thickness was not different between eyes. Nevertheless, at the injured sites, cornea was apparently thicker and corneal endothelial densities were lower than those in the fellow eye. This cornea might decompensate after any other ocular trauma or intraocular surgery.

经过一个月的治疗后，视力、眼压、中央角膜厚度、角膜上皮、前房、视网膜等皆恢復正常，但角膜內皮细胞密度明显减少，受伤部位的角膜亦明显较厚，日后恐有角膜失偿的危险，而这种情况无法藉测量中央角膜厚度显示出来。

Results Of 61 cases, 4 cases (7%) in center 3 mm zone of cornea had mean thickness:(0.439±0.071) mm and polar distance:(3.108±0.904) nun; 8 cases (13%) in 3~5 mm zone had T:(0.328±0.088) mm and p:(3.108±0.904) mm; 28 cases (46%) in 5~7 mm zone had T:(0.320±0.093) mm and p:(3.233±0.381) mm; 21 cases (34%) in 7~9 mm zone had T:(0.340±0.128) mm and p:(3.756±0.539) mm; 61 cases (100%) in 0~9 mm zone had T:(0.336±0.112) mm and p:(3.108±0.904) mm.

结果 61例角膜最薄点平均厚度为(0.336±0.112)mm且平均极距为(3.108±0.904)mm；其中最薄点分布，角膜中央3mm区4例(7%)T为(0.439±0.071)mm且p为(3.108±0.904)mm；角膜3~5mm区8例(13%)T为(0.328±0.088)mm且p为(3.108±0.904)mm；角膜5~7mm区28例(46%)T为(0.320±0.093)mm且p为(3.233±0.381)mm；角膜7~9mm区21例(34%)T为(0.340±0.128)mm且p为(3.756±0.539)mm。

This experiment investigate the expression of TGF- B1 and bFGF in the rabbet corneas to find whether such expression contribute to the corneal wound healing after PRK; and compare the effects of mechanical deepithelialization with chemical deepithelialization PRK on the corneal wound healing.

裂隙灯显微镜下观察角膜Haze及角膜上皮愈合、水肿消退的情况；光镜下观察角膜组织病理学变化并计数不同时间点角膜基质浅层角膜细胞数量的变化；用逆转录-PCR法及免疫组化法检测正常对照组及PRK手术组术后1天、1周、1月、3月不同时点角膜TGF—β1和bFGF的表达情况。

Metholds 236 patients were performed penetrating keratoplasty, in which laser trephination technique was applied. Patients were assigned to four groups:(0) K0D, regular mire;(1) K60, moderately irregular mire;(3) severe irregular, immeasurable mire based on the keratometry value and mires measured with semi-quantitative Ophthalmometer (Type-H, 190071 Zeiss, Jena, Germany).

回顾分析了236例圆锥角膜使用激光环钻技术进行的穿透性角膜移植手术手术，使用角膜曲率计(Ophthalmometer， Type-H， 190071 Zeiss， Jena， Germany)对手术前后的角膜规则程度进行检测，并结合所测出的角膜曲率值和角膜映光图像分成4组：(0)规则组，K0D；(1)轻度不规则组，K0；(2)中度不规则组，K≥60；(3)重度不规则组，K值不能读出，共4组。

Repeated corneal perforation occurred in nine eyes, with primary diseases of herpes simplex keratitis (HSK; four eyes), Mooren ulcer, necrotizing keratitis and scleratitis, bacterial keratitis, and alkali burn. Corneal grafts perforated in 31 eyes, resulting from recurrent HSK, implant autoproteolysis, bacterial infections, recurrent Mooren ulcer, immunologic rejection, trauma, and fungal recurrence.

本研究中有9只眼发生了反复的角膜穿孔，其原发疾病分别为单疱病毒性角膜炎（HSK，4只眼），蚕食性角膜溃疡（2只眼），坏死性角巩膜炎（1只眼），细菌性角膜炎（1只眼）和碱烧伤（1只眼）。31只眼发生了角膜植片穿孔，分别由单疱病毒性角膜炎复发（8只眼），角膜植片自溶（7只眼），细菌感染（6只眼），蚕食性角膜溃疡复发（4只眼），免疫排斥反应（3只眼），外伤（2只眼）和真菌复发（1只眼）引起。

To find out about technologies that are truly "over the horizon" in refractive surgery, we introduce several surgical methods and new trend in the future. These include intracorneal rings, laser thermal keratoplasty, phakic in traocular lens, pico-second intrastromal laser, conductive keratoplasty,scleric expansion devices and customized LASIK.

本文整理介绍数种手术方法：包括有角膜内环扣、高温雷射角膜塑型术、眼内镜片植入术、角膜基质中光雷射、传导式角膜塑形术、巩膜扩张术、完全雷射层状角膜型术以及未来雷射角膜屈光手术之趋势。

During LASIK surgery, central corneal thickness was measured with ultrasonic pachymeter. We created a corneal flap using Mona M2 microkeratome with an intended flap 130 μm, and then central conical thickness was measured again.

在LASIK手术中，我们会先用超音波量角膜厚度，接著用标记角膜皮瓣厚度110μm的Moria M2角膜板层刀切了角膜皮瓣后，再量剩余角膜厚度，两者相减即为角膜皮瓣的厚度。

Corneal allograft is the most effective treatment for corneal blindness,but corneal graft rejective reaction is the main cause of corneal allograft. Corneal neovascularization is one of the most causes of corneal blindness and the high-risk factor of corneal graft rejective reaction.

研究背景同种异体角膜移植是治疗角膜盲最为有效的方法，而角膜移植排斥反应仍然是移植失败的主要原因；角膜新生血管是角膜盲的主要原因，亦是角膜移植排斥反应的高危因素。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。