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The ear edema of the normal and adrenalectomized mice induced by croton oil, vascular permeability formed by histamine in mice and hind paw edema caused by Carrageenin in rats were used to determine the inhibition to acute inflammnation.

提取物对急性炎症的抑制作用采用巴豆油引起的正常小鼠和摘除肾上腺小鼠的耳肿胀、组胺引起的小鼠毛细管通透性以及角叉菜胶引起的大鼠足肿胀进行分析。

Methods:Different doses of CQG were given to mice with swelling feet induced by acetic acid, cotton balling granulation ,and carrageenin.

采用小鼠醋酸扭体法、大鼠棉球肉芽肿法和角叉菜胶所致大鼠足肿胀方法。

Methods:stimulating the animal model of rats with the experimental prostatitis by injecting carrageenin into rat prostates.We compared the model group with other groups which had taken Nanyanxiao granule,and made pathological examination of prostate.

采用向大鼠前列腺组织内注入角叉菜胶的方法复制大鼠前列腺炎模型,并分别对模型组及口服男炎消冲剂后的大鼠组进行前列腺组织病理学检查。

Results showed that natural cow-bezoar,cultured cow-bezoar,with medium or low bilirubin content and chicken bile(0.5 g/kg ig) could significantly inhibit rat paw edema induced by carrageenin and formaldehyde i...

结果表明,天然牛黄,中胆红素培植牛黄、低胆红素培植牛黄和鸡胆汁均能显著地抑制角叉菜胶和甲醛致炎后的大鼠足跖肿胀和炎性组织中的PGE2含量。

Effects of natural cow-bezoar,cultured cow-bezoar with different bilirubin content and chicken bile on rat paw edema induced by carrageenin and formaldehyde and the postaglandin E2 (PGE2) content of inflammatory tissues of rat were determined by foot-digitoplantar turgorneter and UV spectrophotometry.

采用大鼠足跖肿胀法和紫外可见分光光度法,研究了天然牛黄、胆红素含量不同的培植牛黄以及鸡胆汁对大鼠角叉菜胶性和甲醛性的足跖肿胀率和炎性组织中PGE2含量的影响。

In this experiment,Xiaochaihu Oral Liquid was found to possess marked functions of inhibition on hydrops of rat articulatio talocruralis(p.05)induced by Carrageenin,of protection on acute liv- er function damage of rat,of depression of SGPT and LDH(p.01) and inhibition of the fever reaction of rabbit.

观察了小柴胡汤口服液的主要药理作用。研究表明,小柴胡汤口服液有显著抑制角叉菜胶诱发的大鼠踝关节水肿(p.05),保护四氯化碳所致的大鼠急性肝功能损害,有极显著降低血清SGPT及LDH的作用(P.01)。对家兔发热反应也有较好的抑制作用。

Results showed that natural cow-bezoar,cultured cow-bezoar,with medium or low bilirubin content and chicken bile(0.5 g/kg ig) could significantly inhibit rat paw edema induced by carrageenin and formaldehyde in rat.

结果表明,天然牛黄,中胆红素培植牛黄、低胆红素培植牛黄和鸡胆汁均能显著地抑制角叉菜胶和甲醛致炎后的大鼠足跖肿胀和炎性组织中的PGE2含量。

Results The extract remarkably inhibited the contraction caused by histamine and acetylcholine, as well as the ovalbumin sensitized allergic constriction of isolated ileum smooth muscle of guinea pigs. It could inhibit the increase of capillary permeability induced by acetic acid in mice, inhibit the mice paw edema produced by carrageenin and reduce the production of PGE 2 in inflammatory tissues.

结果:辛夷二氯甲烷提取物对组胺、乙酰胆碱(Ach引起的豚鼠离体回肠收缩具有显著的抑制作用,并能抑制卵白蛋白所致的豚鼠离体回肠过敏性收缩,对HAc引起的小鼠腹腔毛细血管通透性增高具有抑制作用,能显著抑制角叉菜胶引起的小鼠足肿胀,并减少前列腺素E2(PGE2)在炎症组织中产生。

RESULTS Xiaocuoling at the concentration of 2.5、5.0、10.0g.kg-1 obviously inhibited the paws swelling induced by carrageenin in mice and the granuloma with cotten pellet in rats,decreased the penetration of blood capillary caused by histamine,increased the activity of peroxide hydrogenase in RBC,reduced the reaction of the torsive body induced by acetic acid in mice,and had no effects on the serum concentrations of testosterone of serum in male rats.

结果:消痤灵颗粒 2.5、5.0、10.0g.kg-1可显著抑制角叉菜胶所致的小鼠足趾肿胀和大鼠棉球肉芽肿,降低由组胺诱导的小鼠皮肤毛细血管通透性的增加,提高红细胞过氧化氢酶的活力。对乙酸致小鼠扭体反应有抑制作用。对雄性大鼠血清睾酮含量无影响。

Methods Animal inflammatory models were established by injection of dimethylbenzene for mice ear swelling, carrageenin for rat footpad, cotton pellet wool for rat granuloma respectively. The content of prostaglandin E2(PGE2) and leukotriene B4(LTB4) from peritoneal macrophages were measured by RIA and RP-HPLC respectively.

采用二甲苯诱导的小鼠耳肿胀、角叉菜胶诱导的大鼠足肿胀、棉球诱导的大鼠肉芽肿模型观察TFC的抗炎作用;分别采用放射免疫法和反相高效液相色谱法检测TFC对大鼠腹腔巨噬细胞产生前列腺素E2(PGE2)和白三烯B4(LTB4)的影响。

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