角化过度

Most ingredients of the nuts may hurt the oral mucosa mechanically and chemically. Betel nut chewing has been proved to cause epithelial atrophy, hyperkeratosis, even oral cancer.

槟榔中各种成分会对口腔粘膜产生机械与化学性伤害，许多研究已证实槟榔嚼食者的粘膜常会出现上皮萎缩或过度角化增生，甚至引发口腔癌。

Our skin every day on their own metabolism, resulting from the basal cells gradually reach the skin surface, and then become a cuticle, the skin hyperkeratosis cycle is usually around 28 days, due to the environment, season, UV, rest is not normal and other factors, sometimes cause slow metabolism, so our skin piles up thicker stratum corneum, horny excessive accumulation, it will allow a transparent discussion so that the skin does not feel a sense of, and have lost the flexibility of the original, so fixed and the appropriate exfoliation, dander can be removed, so that the skin is more translucent.

我们的肌肤每天都会自行新陈代谢，由基底层产生的细胞会慢慢的到达肌肤的表面，然后成为角质层，皮肤的角化周期通常约为28天，由于环境、季节、紫外线、作息不正常等因素，有时会使新陈代谢变得缓慢，所以我们的皮肤表面角质层越堆越厚，角质过度的堆积，就会容议让肌肤感觉没有透明感，也失去原本的弹性，所以固定且适当的去角质，可以将皮屑去除，让肌肤更晶莹剔透。

Ten days after admission, generalized hyperkeratotic and hyperpigmented plaques with symmetrical scaly and erosive eczematous lesions around the body orifices were observed.

十天后，他全身出现过度角化的深色斑块，同时在身体的开口处出现对称性脱屑糜烂湿疹性病灶。

Abnormal laboratory tests were not found in all patients. X-ray showed soft tissue swelling at involved joints in all patients and MRI showed pachyderma in 1 patients. Epiderm hyperkeratosis and subcuticula fibroplasias were found at PIP 5 joints in 1 patient.

实验室检查未发现异常；6例双手X线检查均见受累关节周围软组织肿胀；1例左手核磁共振成像见：近端指间关节周围软组织增厚；1例左手第5PIP关节膨大处软组织活检见：表皮过度角化，真皮层纤维组织增生。

The typical histopathologic features include a keratotic plug in the dilated follicular orifice and spongiosis of the infundibular epithelium. However, recently, another histopathologic observation has been reported, that of numerous foamy histiocytes in the peri-infundibular dermis.

病理组织的典型发现包括毛囊开口有过度角化的现象，在毛囊漏斗部可见海绵样水肿的变化，在近来的文献报告中亦发现可以存在有泡沫状组织细胞聚集在毛囊漏斗部的周围。

The results showed:(1) The histological changes of KC were in fact a wound-repair process;(2) The increased melanin in KC coordinated with "multi-overlapping screen" effect, a result of multiple layers of "supranuclear cap", was the direct cause of hyperpigmentation of the graft and (3) The hydrolytic disturbance of melanin in KC and the longer life span of the KC were probably the important reasons for the increase of melanin in the epidermis.

结果表明，角朊细胞的组织学改变实际上是一个损伤后修复的过程；角朊细胞内黑色素含量增加及出现的多层次的&核上帽&状分布而形成的&多重帘幕&效应，是皮片过度色素化的直接原因；黑色素在角朊细胞内的降解障碍及角朊细胞更新周期延长可能是表皮内黑色素含量增多的重要原因。

OBJECTIVE Cholesteatoma of the middle ear is an inflammatory disease characterized by the presence of hyperproliferative keratinizing squamous epithelium in the middle ear cavity and destruction of adjacent bone.

目的：中耳胆脂瘤是一种以鳞状角化上皮过度增殖和邻近骨质破坏为特征的炎性疾病。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。