角化的

The average ADC was lower in the primarily focus of nasopharyngeal non cornification anaplastic carcinoma and metastatic lymph nodes than normal control group.

结果 鼻咽非角化型未分化癌不同中医证型的平均ADC值的差异有显著统计学意义(x2=15.987，P＝0.000)，火毒困结型的平均ADC值明显高于痰浊结聚型、气血凝结型，且差异有显著统计学意义(P＜0.01)；鼻咽非角化型未分化癌原发灶及其转移性颈部、咽后淋巴结的平均ADC值均低于对照组，且差异有显著统计学意义(P＜0.01)。

Hyperkeratosis or parakeratosis on an otherwise negative Pap smear is not a marker for significant CIN and may be related to infection or trauma with inflammation, such as from use of a diaphragm .

在其他的巴氏涂片阴性的片子上的过度角化或角化不全，这种情况可能与感染相关，也可能与感染合并血肿相关，，如使用隔膜。

Hyperkeratosis or parakeratosis on an otherwise negative Papsmear is not a marker for significant CIN and may be related toinfection or trauma with inflammation, such as from use of a diaphragm .

在其他的巴氏涂片阴性的片子上的过度角化或角化不全，这种情况可能与感染相关，也可能与感染合并血肿相关，，如使用隔膜。

Results: The PCNA mean labelling index was 48.84％± 13.63％, and the apoptotic labelling index was12.26‰± 5.20‰. The Kaplan-Meier survival curves showed that the postoperative survival time of the patient was shorter when the tumor infiltrated to the adventitia of esophagus,with lymph node metastasis, without keratinization, PI ≥ 40％ or AI＜10‰. Using forward multivariate Cox regression analysis, only the parameters of pN category and PI could be verified as independent prognostic factors.

结果：36例手术切除的食管鳞癌组织平均PCNA表达指数(PCNAlabellingindex，PI)为48.84％±13.63％，细胞凋亡指数(apoptosisindex，AI)为12.26‰±5.20‰；PI升高与患者年龄小、分化程度低、有淋巴结转移和肿瘤进行性浸润呈正相关，而AI升高与分化程度高、角化明显呈正相关；绘制Kaplan－Meier生存曲线，发现病变侵及食管外膜、有淋巴结转移、无角化、PI≥40％或AI＜10‰的患者术后生存率明显降低；COX比例风险模型分析，发现只有淋巴结转移和PI是影响预后的独立因素。

The invention provides a parakeratosis inhibitor, a pore-shrinking agent or an agent for preventing/ameliorating rough skin which has a function of inhibiting parakeratosis, shrinking a pore, preventing/ameliorating rough skin or the like, does not have any safety problem such as sensible irritation and has high safety.

本发明提供具有抑制角化不全、收缩毛孔、防止/改善皮肤粗糙等功能，在刺激感觉等安全性上没有问题，安全性高的角化不全抑制剂、毛孔收缩剂或皮肤粗糙防止/改善剂，本发明还提供配合具有上述功能的化合物的皮肤外用组合物。

Therefore, by contrasting and analyzing those different conditions and m acroscopic environment in our country and western countries,the differences in i mplementing a diversification strategy in our enterprises and western ones can b e found.

提出了现阶段我国企业实行多角化经营战略应根据自身条件和宏观环境审慎决策，不可盲目套用国外模式的结论，从而对我国企业多角化战略的实际操作有一定的参考价值。

Results there are 22 affected patients (10 males and 12 females with approximately equal sex ratio) and the mean age of onset was 16 years old.fifteen patients had positive family history.the major symptom experienced was itching.keratotic papules were invariably present in our patients and mixed pattern with seborrheic plus flexural involvement was the commonest phenotypic variation.all of them had acral signs; 36.36% patients had oral mucosal lesions.lesions were most frequently found on face,ears and back of ears,neck.focal acantholytic dyskeratosis with corps rounds and grains were the usual histopathological findings.

结果 22例患者中有女10例，男12例，男女比例基本相当。平均发病年龄16岁。其中15例有家族遗传史。主要的症状是瘙痒。多在皮脂溢出部位和屈侧皮肤可见油腻性角化性丘疹，且全部病例肢端受累，36.36%患者口腔有皮损。最常见部位依次为面部、耳部和耳后、颈部。局限性棘层松解性角化不良及其产生的圆体和谷粒是最常见的组织病理学改变。

KCOT epithelial cells could be serially cultured in vitro in K-SFM by techniques suggested in this study.

采用无血清的角化细胞培养基可在体外进行牙源性角化囊性瘤上皮细胞的连续培养。

Objective The GJB2, GJB6 and GJB3 genes are related to hereditary deafness and keratoderma. To investigate the genetic causes, we recruited a Chinese family and screened the proband with syndromic deafness and palmoplantar keratoderma for mutations in these three genes and analyzed the phenotype and hereditary traits.

目的 GJB2、GJB6、 GJB3基因与遗传性耳聋及角化病有关，以GJB2、 GJB6、 GJB3基因为候选基因，研究1例伴有掌跖角化病的综合征型耳聋先证者的分子病因，探讨其表型及遗传特征。

Keratinizing squamous metaplasia is a risk factor for subsequent deelopment of carcinoma and other complications such as bladder contracture and obstruction.

鳞状化生可发生在膀胱的各个部位，但以前壁最为常见。鳞化区呈白色或灰白色，如鳞化区有重度角化时，则该处呈不规则隆起似有癌变。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。