角化不良

Other cells are metaplastic or atypical metaplastic cells and parakerototic or atypical parakeratotic cells, should be in ASCUS category.

其他细胞是化生或非典型化生和角化不良或非典型角化不良细胞；应该是ASCUS的范畴。

Multiple skin biopsies with serial sections were performed. Histpathology showed hyperkeratosis, hypergranulosis and papillomatosis with a typical picture of "church spires", but no dyskeratosis or parakeratosis was found.

经过多处切片及连续切面检查，在病理下可见过度角化、颗粒层增生及乳突状增生形成典型的「教堂尖塔」样变化，但并未发现不完全角化及角化不良的情形。

Acantholysis and dyskeratosis are the typical histological findings.

棘层松解和角化不良是典型的病理改变。

We did not identify any of the classic features of dyskeratosis congenita in five of the six families.

在6 个家庭中，有5 个家庭未发现先天性角化不良的任何典型特征。

We did not identify any of the classic features of dyskeratosis congenita in five of the six families.

在这6个家族成员中有5个我们并没有证实有任何典型的先天性角化不良特征。

Germ-line mutations in the genes hTERT and hTR, encoding telomerase reverse transcriptase and telomerase RNA, respectively, cause autosomal dominant dyskeratosis congenita, a rare hereditary disorder associated with premature death from aplastic anemia and pulmonary fibrosis.

分别编码端粒末端转移酶反转录酶和端粒酶RNA的hTERT和hTR基因的种系突变导致常染色体显性先天性角化不良，它是一种罕见的因为再生障碍性贫血和肺纤维化而早亡的遗传性疾病。

Dyskeratosis congenita is a rare inherited disorder characterized by the triad of heterochromia-like pigmentation, nail dystrophy and mucosal leucoplakia in the mouth or vagina.

先天性角化不良是一种少见的先天遗传性皮肤病，其临床三联征包括：甲板营养不良，口腔或阴道等可出现白斑，皮肤异色症样的色素沉着。

Results there are 22 affected patients (10 males and 12 females with approximately equal sex ratio) and the mean age of onset was 16 years old.fifteen patients had positive family history.the major symptom experienced was itching.keratotic papules were invariably present in our patients and mixed pattern with seborrheic plus flexural involvement was the commonest phenotypic variation.all of them had acral signs; 36.36% patients had oral mucosal lesions.lesions were most frequently found on face,ears and back of ears,neck.focal acantholytic dyskeratosis with corps rounds and grains were the usual histopathological findings.

结果 22例患者中有女10例，男12例，男女比例基本相当。平均发病年龄16岁。其中15例有家族遗传史。主要的症状是瘙痒。多在皮脂溢出部位和屈侧皮肤可见油腻性角化性丘疹，且全部病例肢端受累，36.36%患者口腔有皮损。最常见部位依次为面部、耳部和耳后、颈部。局限性棘层松解性角化不良及其产生的圆体和谷粒是最常见的组织病理学改变。

Other cells are metaplastic or atypical metaplastic cells and parakerototic or atypical parakeratotic cells, should be in ASCUS category.

其他细胞是化生或非典型化生和角化不良或非典型角化不良细胞；应该是ASCUS的范畴。掌握吾心。

It is caused by mutations in dyskerin-encoding genes, telomerase-encoding RNA component genes and reverse transcriptase genes, as well as other uncharacterized genes. There are three inherited forms, including X-linked, autosomal dominant and autosomal recessive inheritance.

先天性角化不良是与编码角化不良蛋白基因、编码端粒酶的RNA组份基因、编码端粒酶的逆转录酶基因突变及其他未确认的致病基因突变引起的基因病，其遗传方式有：X-性联隐性遗传、常染色体显性遗传及常染色体隐性遗传。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。