角化

BACKGROUND: Photodynamic therapy is a highly effective treatment for actinic keratoses; however, it is time consuming and often painful for the patient.

背景：光动力疗法是一种治疗化性性角化病非常有效的方法；但是，此疗法费时且常常引起患者的疼痛。

After 3 months, the number of actinic keratoses had decreased significantly in all 3 treatment groups — 92% in the laser group, 89% in the acid group, and 83% in the fluorouracil-cream group.

3个月后，三个治疗组的光化性角化病患者人数显著减少—雷射组 92%、酸剥离组89%、fluorouracil-乳膏组 83%，没有人在治疗中感到有不良反应。

They enrolled 21 subjects who had actinic keratoses and moderate to severe photoaging.

患者：21例健康志愿者，年龄56-85岁，患有光化性角化病和光损伤。

This article reviews immunoregulatory mechanism and the application of imiquimod to cauliflower excrescence,actinic keratosis,Bowen diseases and cutaneous tumor.

本文对咪喹莫特的免疫调节机制及其在尖锐湿疣、光化性角化病、Bowen病和皮肤肿瘤中的应用予以综述。

The new study included 21 healthy volunteers with sun-damaged skin and actinic keratoses -- skin lesions that could develop into skin cancer -- on their faces.

该项研究是针对21位志愿者展开的，他们脸部的皮肤均被晒伤且患有光化性角化病-一种可演变为皮肤癌的皮肤损害。

Objective:To explore the clinicopathological,immunohistochemical feature and therapeutic methods of hyperkeratosis lenticularis perstans.

目的：提高对持久性豆状角化过度症的认识，探讨其临床、病理、免疫组化特征及治疗方法。

Methods:Analyze the clinicopathological,immunohistochemical feature and therapeutic methods of a case of hyperkeratosis lenticularis perstans.

分析1例持久性豆状角化过度症患者的临床、病理、免疫组化特征及治疗方法。

There is also in the skin lesions of psoriasis immune globulin, complement, anti-IsA factor, anti-keratin antibodies and parakeratotic nuclei antibody, etc., these factors result in abnormal T lymphocytes in the immune cycle of separatist injury and the number of T lymphocytes in significantly reduced, such as the Con A stimulus-response is reduced, while phytohemagglutinin and pokeweed mitogen factor is a normal reaction, this phenomenon is to support T-cell subsets flawed.

在牛皮癣的皮损中还有免疫球蛋白、补体、抗IsA因子、抗角蛋白抗体及角化不全细胞核中有抗体等，这些免疫异常因子造成T淋巴细胞的周期分裂性损伤和T淋巴细胞数量明显减少，如对刀豆球蛋白的刺激反应性下降，而对植物血凝素和商陆有丝分裂因子却反应正常，这种现象支持T细胞亚群存在缺陷。

Horny layer is the outmost layer of epidermis, its thickness is decided by different parts of human body, it's about 0.02mm at the thinnest parts, and 0.5mm at the thickest. It is made up of 5-10 layers of enucleated cornified cells that contains keratin and horny fat, which has the capability of resisting weak acids and weak bases , they array closely and become a natural barrier to moisture content and some chemical substances, so as to prevent the water logging of bodily fluids and endosmose of chemical substances.

角质层是表皮的最外层，其厚度依身体部位的不同而定，最薄处约0.02mm，最厚处约0.5mm由5-10层含有角蛋白和角质脂肪的无核角化细胞组成，角质层细胞有抵抗弱酸弱碱的能力，角质层细胞排列紧密，对水分及一些化学物质有天然屏障作用，因而可以阻止体内液体的水渗和化学物质的内渗。

RESULTS: Transplanted AS had a favorable fusion between tissue-engineered skin and self-skin on the 3rd day after grafting with a few of ingrowths of capillaries.

结果：AS组在移植第3天，移植的组织工程皮肤与自体皮肤能够很好地融合，有少量毛细血管长入移植物，皮肤移植物颜色与自体皮肤颜色接近；随着时间的延长，移植物中毛细血管的数量逐渐增多，表皮层清晰可见基底层、棘细胞层、颗粒层和角质层，角化现象加强，有角化物脱落；真皮层细胞数量增多，网架逐渐降解，分泌的细胞外基质成份增多；第14天，创面基本愈合；修复区皮肤颜色与正常皮肤颜色非常接近，瘢痕很小，无需进行二次植皮。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。