角化

Some cases, there may be a high degree of hyperkeratosis nose and corner pads.

部分病例可出现鼻部和角垫高度角化。

Porokeratosis is a clonal disorder of keratinization that is histologically characterized by the presence of a cornoid lamella.

PK是一群角化异常的疾病，病理下的特徵是可见所谓的角样板。

The expression had significant difference between ASEH and carcinomas depend ing on the differentiation degree.The expression rates of P53 in SEAH,CIS and ISEC were 6.66%,8.00%and 26.67%,respectively.it was significantly different bet ween keratinized and non-keratinized type of SEC.

表达在不典型增生与癌之间差异有显著性，且和组织分化程度有关。P53在三者之间表达率分别为6.66%，8.00%和2 6.67%，角化型和非角化型鳞状上皮癌之间表达差异有非常显著意义(P.01)。

KCOT epithelial cells could be serially cultured in vitro in K-SFM by techniques suggested in this study.

采用无血清的角化细胞培养基可在体外进行牙源性角化囊性瘤上皮细胞的连续培养。

Objective The GJB2, GJB6 and GJB3 genes are related to hereditary deafness and keratoderma. To investigate the genetic causes, we recruited a Chinese family and screened the proband with syndromic deafness and palmoplantar keratoderma for mutations in these three genes and analyzed the phenotype and hereditary traits.

目的 GJB2、GJB6、 GJB3基因与遗传性耳聋及角化病有关，以GJB2、 GJB6、 GJB3基因为候选基因，研究1例伴有掌跖角化病的综合征型耳聋先证者的分子病因，探讨其表型及遗传特征。

It is caused by mutations in dyskerin-encoding genes, telomerase-encoding RNA component genes and reverse transcriptase genes, as well as other uncharacterized genes. There are three inherited forms, including X-linked, autosomal dominant and autosomal recessive inheritance.

先天性角化不良是与编码角化不良蛋白基因、编码端粒酶的RNA组份基因、编码端粒酶的逆转录酶基因突变及其他未确认的致病基因突变引起的基因病，其遗传方式有：X-性联隐性遗传、常染色体显性遗传及常染色体隐性遗传。

Keratinizing squamous metaplasia is a risk factor for subsequent deelopment of carcinoma and other complications such as bladder contracture and obstruction.

鳞状化生可发生在膀胱的各个部位，但以前壁最为常见。鳞化区呈白色或灰白色，如鳞化区有重度角化时，则该处呈不规则隆起似有癌变。

The NPC tissue was all EBV-positive except for one sample, which was identified as keratinizing carcinoma, but the control samples were all negative for EBV infection, which was correlated with CD25 expression.

对照组选取鼻咽慢性炎症组织。结果 CD25淋巴细胞在鼻咽癌组织中比在鼻咽慢性炎症组织中的表达明显升高，差异具有显著性意义(P.001)，且在未分化癌中表达高于角化型癌和非角化型癌(P.05)。原位杂交显示EB病毒与CD25淋巴细胞高表达有关。

Mean ApoL I of keratinizing types(15.77±4.34) was significantly higher than those of nonkeratinizing types (8.03±1.70). The ApoL I increased from 6.51±0.58 with poorly differentiated cancers through 10.58±2.90 with moderately differentiated cancers to 18.41±4.49 with well differentiated cancers. There was no apparent correlation between ApoL I and sex, age, tumor size, tumor location and tumor infiltrative depth. The Kaplan-Meier survival curves between ApoL I＜10‰ and ApoL I≥10‰ have significant difference, while the former has a shorter survival time.

角化型ApoL I高于非角化型(P＜0.01)；肿瘤分化越好，细胞凋亡越多，低度、中度、高度分化ApoL I有差异(P＜0.05)；不同性别、年龄、肿瘤部位、长度、深度，其ApoL I并无差异；以10‰为界将ApoL I分组绘制Kaplan-Meier生存曲线，ApoL I≥10‰组术后生存率高。

Secondly, this dissertation has studied systematically the mechanism of the diversified growth, vertical integration growth, and quasi—vertical integration growth of the firm.

第二，系统深入地分析了企业多角化型、纵向一体化型、准一体化型成长的机制，分析了各种成长模式的正面效应、负面效应，提出了多角化型成长的三重检验，对比了纵向型成长诸模式的特征。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。