角化

The average ADC was lower in the primarily focus of nasopharyngeal non cornification anaplastic carcinoma and metastatic lymph nodes than normal control group.

结果 鼻咽非角化型未分化癌不同中医证型的平均ADC值的差异有显著统计学意义(x2=15.987，P＝0.000)，火毒困结型的平均ADC值明显高于痰浊结聚型、气血凝结型，且差异有显著统计学意义(P＜0.01)；鼻咽非角化型未分化癌原发灶及其转移性颈部、咽后淋巴结的平均ADC值均低于对照组，且差异有显著统计学意义(P＜0.01)。

The effects of FPL andits three ingredients on growth of ovary,on micro-and ultra-structure andAlkaline phosphatase activity of endometrium,on structure andkeratinization rate of exfoliated cells in vaginal epithelium in mice,onmicrocirculation in rat and on uterine kinesis in rabbit were respectivelyobserved by the techniques of light and electron microscopes,histochemistry,microcirculation and organ cinetography.The results have confirmed themechanism of FPL for the sterility caused by ovary standstill and persistentcorpus luteum to be as follows:(1) a weak estrogen-like role which canprompt development of ovary,proliferation and secretion of endometrium andvaginal epithelium and cornification of exfoliated cells in vaginal epithelium;(2)enhancing AKP's activity of endometrium;(3)improving microcirculation;(4) exciting uterus.

分别采用光学显微镜和电子显微镜技术、组织化学技术、微循环技术和器官运动描记等现代医学实验技术，观察了促孕液对小白鼠的卵巢发育、子宫内膜的显微和超微结构和碱性磷酸酶活性、阴道上皮结构和脱落细胞的角化率、对大白鼠的微循环和对家兔的子宫运动的影响，结果证实了促孕液治疗卵巢静止、持久黄体的机理：(1)微弱的雌激素样作用，能刺激卵泡发育，促进子宫内膜和阴道上皮增生、分泌和阴道上皮脱落细胞角化；(2)提高子宫内膜碱性磷酸酶的活性；(3)改善微循环；(4)促进子宫运动。

Keratosis clinically with mats, nasal hyperkeratosis of cases caused by multiple neurological symptoms.

临床上以脚垫角化、鼻部角化的病例引起神经性症状的多发。

Hyperkeratosis or parakeratosis on an otherwise negative Pap smear is not a marker for significant CIN and may be related to infection or trauma with inflammation, such as from use of a diaphragm .

在其他的巴氏涂片阴性的片子上的过度角化或角化不全，这种情况可能与感染相关，也可能与感染合并血肿相关，，如使用隔膜。

Hyperkeratosis lenticularis perstans is a rare keratoid dermatosis and CD4 - positive T cell - mediated immune reaction may play an important role in the pathogenesis of this disease.

持久性豆状角化过度症是一种临床少见的角化性皮肤病，CD4＋T细胞介导的免疫反应在HLP的发病中可能起着重要的作用，异维A酸口服及外用治疗该病有效。

Hyperkeratosis or parakeratosis on an otherwise negative Papsmear is not a marker for significant CIN and may be related toinfection or trauma with inflammation, such as from use of a diaphragm .

在其他的巴氏涂片阴性的片子上的过度角化或角化不全，这种情况可能与感染相关，也可能与感染合并血肿相关，，如使用隔膜。

Dysplasias may also involve the vulvar epithelium, seen here at the right with overlying hyperkeratosis (producing an area of leukoplakia ), with more normal keratinizing squamous epithelium at the left.

不典型性增生可累及外阴上皮，右侧为表层的过度角化，左侧为萎缩的角化的鳞状上皮。

Porokeratosis is a keratinization disorder characterized by multiple small lesions with an elevated thick keratotic border and central atrophy.

汗管角化症是一种少见的慢性角化性皮肤病，以中央轻度萎缩边缘堤状角质嵴围绕的皮损为特征。

Results: The PCNA mean labelling index was 48.84％± 13.63％, and the apoptotic labelling index was12.26‰± 5.20‰. The Kaplan-Meier survival curves showed that the postoperative survival time of the patient was shorter when the tumor infiltrated to the adventitia of esophagus,with lymph node metastasis, without keratinization, PI ≥ 40％ or AI＜10‰. Using forward multivariate Cox regression analysis, only the parameters of pN category and PI could be verified as independent prognostic factors.

结果：36例手术切除的食管鳞癌组织平均PCNA表达指数(PCNAlabellingindex，PI)为48.84％±13.63％，细胞凋亡指数(apoptosisindex，AI)为12.26‰±5.20‰；PI升高与患者年龄小、分化程度低、有淋巴结转移和肿瘤进行性浸润呈正相关，而AI升高与分化程度高、角化明显呈正相关；绘制Kaplan－Meier生存曲线，发现病变侵及食管外膜、有淋巴结转移、无角化、PI≥40％或AI＜10‰的患者术后生存率明显降低；COX比例风险模型分析，发现只有淋巴结转移和PI是影响预后的独立因素。

"Long-term skin cancer and actinic keratoses surveillance continue to be important,and repeated resurfacing procedures or courses of topical agents,such as fluorouracil or imiquimod, may be necessary," the researchers write."A largerstudy comparing trichloroacetic acid resurfacing for actinic keratoses reductionand nonmelanoma skin cancer prophylaxis would help validate the superiority ofthis resurfacing technique over the carbon dioxide laser andassess its cost-effectiveness compared with photodynamic therapyor imiquimod treatment." They cite improved patient compliance in the trichloroacetic-acid group, ease of performance in the outpatient setting, andsubjective measures of better tolerance as reasons this procedure is an attractive alternative to repeated courses with topicalagents or laser resurfacing.

研究者指出，长期皮肤癌和光化性角化病之监测仍是重要的，反覆的皮肤重建整形步骤、或外用制剂如fluorouracil 或 imiquimod的反覆疗程也可能是必须的；一个比较三氯醋酸皮肤重建整形以减少光化性角化病和预防非黑色素皮肤癌的大型研究，将可有助於确定其优於二氧化碳雷射的优势，以及评估其和光动力治疗或 imiquimod治疗之花费效益比比较；他们举例说，三氯醋酸组病患之遵医嘱性增加、门诊病患也容易进行、个案之测量耐受度比较佳，这些都是重复疗程时比外用药剂或雷射更有吸引力的理由。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。