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To Dec. 2003 years in Yuxi city People's Hospital. RESULTS: The proportion of G- bacilli were much. The opportunistic pathogen's and Yeasts detected rate rose obviously. Most drug sensitive tests showed the drug-fast rate turned to be high. Escherichia coli, Salmonella and Klebsiella and so on to fluoroquinolones was 50~97.7%. These bacteria to imipenem showed excellent activity. MRS resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, gentamycin, trimeth/sulfa and cefazolin were above 50%. Streptococcus resistant to major β-lactams-penicillin, aminoglycosides, macrolides, tetracyclines and sulfonomides were highness.

结果:G-杆菌比例居多,条件致病菌和酵母样真菌检出机会显著增高;药敏结果显示多数临床细菌对常用抗生素的耐药趋势在不断上升;大肠埃希菌、沙门菌和克雷伯菌等G-杆菌对喹诺酮类药物的耐药率在50%~97.7%,亚胺培南则对阴性杆菌有较高的敏感覆盖率;耐甲氧西林葡萄球菌对环丙沙星、诺氟沙星、氯洁霉素、四环素、红霉素、庆大霉素、复方新诺明和头孢唑啉的耐药率均在50%以上,链球菌对多数β内酰胺类青霉素、氨基糖苷类、大环内酯类、四环素类以及磺胺类药物呈高度耐药。

Equation of motion capping mechanism and calculation formula of design parameters were deduced.

推导了锁盖机构的运动方程及参数的计算公式,为设计西林瓶锁盖机提供理论参考。

It suggests that resistance to metronidazole and clarithromycin is the main cause of failure of eradication therapy for H.

对阿莫西林的耐药率较低。H.pylori对抗生素耐药是导致根除治疗失败的主要原因。

Based on the previous literatures, the following major innovation works were carried out in this dissertation:(1) The derivatization reaction conditions of ephedrine and pseudoephedrine with sensitive derivation reagent in aqueous system were studied and two new methods were developed for the assay of them by microemulsion electrokinetic chromatography and micellar electrokinetic chromatography with LIF detection. The sensitivity and analysis times were greatly improved compared with the previous reports;(2) A new method of CZE with indirect LIF detection was developed for the simultaneous determination of six coumarin compounds (esculin, esculetin, isofraxidin, genistein, naringin and sophoricoside) with fluorescein as the probe. The proposed method enlarges the application range of LIF detector, and provides new approach for the analysis of certain compounds difficult to derivatize;(3) Based on the above research, an MEKC with indirect LIF detection method for the simultaneous determination of adenine and guanine in DNA extracts from fungus, maize and soybean was established;(4) A new method for the investigation of the complexes formed between human serum albumin and ampicillin sodium under the simulated physiology conditions using laser light scattering technique was developed.

该论文在综述前人工作的基础上,开展了如下未见文献报道的创新性的研究工作:(1)使用灵敏的衍生试剂对麻黄碱和伪麻黄碱在水体系中的衍生反应条件进行了系统研究,建立了微乳电动色谱-激光诱导荧光检测法和胶束电动色谱—激光诱导荧光检测法测定麻黄碱和伪麻黄碱的灵敏分析新方法,与以前的报道相比,灵敏度和分析时间均有很大改善;(2)使用荧光素钠作为背景荧光试剂,建立了同时分析测定六种黄酮类化合物(秦皮甲素、秦皮乙素、异秦皮定、染料木素、柚皮苷和槐角苷)的毛细管区带电泳—间接激光诱导荧光检测新方法,扩大了激光诱导荧光检测的应用范围,对难衍生化合物的分离分析提供了一种新思路和新途径;(3)以荧光素钠作为背景荧光试剂,建立了一种用于同时测定食品提取DNA中的腺嘌呤和鸟嘌呤含量的胶束电动色谱—间接激光诱导荧光检测新方法;(4)用动态和静态激光散射法研究了模拟生理条件下人血清白蛋白与氨比西林钠盐相互作用所形成的复合物,为药物分子与蛋白质的相互作用、药代动力学等的研究提供了一种新思路。

Objectives To investigation and analysis the infected prevail tendency of methicillin resistant staphylococcus aureus in intensive care unit of zonal hospital, to prevent the fulminate spreading of MESA and adopt effective therapeutic measure.

目的 通过对区级医院重症监护病区耐甲氧西林金黄色葡萄球菌感染的流行初期进行调查和分析,以防止MRSA的暴发流行以及能够采取有效治疗措施。

By spraying the watery solution of AMP and ASA with different concentrations to the entire carries of chrysanthemum "tangyujinqiu" in the vegetable growing and the green bud stage. Then the changes of the soluble protein, the soluble sugar, the hyperoxide mutase the vigor, the ultra oxygen anion O2(superscript - the production rate, and the third dial the content, the relative conductivity and dry weight/fresh weight was been measured in the entire flowering season.

以不同浓度的氨苄西林+抗坏血酸水溶液对菊花"唐宇金秋"品种在营养生长期和绿蕾期进行全株喷雾处理,测定整个花期花瓣可溶性蛋白、可溶性糖含量、超氧化物歧化酶活力、超氧阴离子O2(上标-产生速率、丙二醛含量、相对电导率及干鲜比的变化。

Objective To explore the relationship between the illuminance and the observed order of reaction of photodegradation of nitrofurazone solution.

摘要目的研究呋喃西林水溶液光解反应的表观反应级数和光照度的关系。

Methods Rabbits were administered by intravaginal amoxicillin and metronidazole solution, then the experimental vaginitis model were established by E. coli and Staphylococcus aureus, were treated with lactobacilli lysates, lactobacilli lysates in lower concentration, lactobacillus fermented broth, the probiotic lactobacillus and N. S for 7 days respectively. The variety in vaginal microecosystem were analysed and investigated.

用阿莫西林和甲硝唑接种家兔建立脱污染模型,再用大肠埃希菌和金黄色葡萄球菌的混合液接种,建立实验性感染模型后,随机分为5组,分别用乳杆菌裂解物原液、裂解物稀释液、发酵上清液、乳杆菌活菌制剂及生理盐水进行治疗,分析和考察阴道菌群变化。

RESULTS The contents of mezlocillin sodium mixed with fructose injection and invert sugar injection were stable within six hours,and the mixed solutions were clear with stable pH values.

美洛西林钠在多种输液中稳定性良好,但笔者未见其在果糖注射液和转化糖注射液中的稳定性考察。

METHODS Mezlocillin sodium in fructose injection and invert sugar injection was assayed with HPLC at different time points after being mixed,and the appearance and pH values of the mixed solutions were observed as well.

美洛西林钠属半合成青霉素类抗生素,具有高效、广谱杀菌作用,是临床常用的抗感染治疗药物之一。

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这一模式非常关注商人的网络信用基础。

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