西林

Of Staphylococcus aureus was methicillin-resistant Staphylococcus aureus and 77.35% of coagulase negative Staphylococcus was methicillin-resistant coagulase negative Staphylococcus respectively.

耐甲氧西林金黄色葡萄球菌和耐甲氧西林凝固酶阴性葡萄球菌分别占金黄色葡萄球菌和凝固酶阴性葡萄球菌的60.58%和77.35%。

Then the detection rates of MRS on the three phenotype testing methods were compared with each other. Results A total of 187 clinical staphylococcus isolates were tested including 78 staphylococcus aureus isolates and 109 coagulase negative staphylococcus.

分别采用头孢西丁纸片扩散法、苯唑西林盐琼脂纸片扩散法、Vitek-32 AMS检测187株临床分离葡萄球菌对甲氧西林的耐药性，并比较这三种方法对MRS检出率的差异。

Results: The proportion of Gram-negative bacilli rose obviously, so did the opportunistic pathogen's and Yeasts detected rate. Most drug sensitive tests showed the drug-fast rate turned to be high. Escherichia coli, Salmonella and Citrobacter resistant and so on to fluoroquinolones was 57%~97%. These bacteria to imipenem showed excellent activity. Meticillin-resistant-staphylococcus resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, cefazolin and ampicillin were 40.9%, 42.4%, 63.6%, 72.2%, 85.9%, 100.0% and 100.0%, respectively Streptococcus and Enterococcus resistant to major β-lactams-penicillin, aminoglycosides, macrolides, tetracyclines and sulfonamides were between 36.0% to 100.0%.

结果：革兰阴性杆菌比例显著升高，条件致病菌和酵母样真菌检出机会显著增多；药敏结果显示多数临床细菌对常用抗生素的耐药趋势在不断上升；大肠埃希菌、沙门菌和枸橼酸杆菌等革兰阴性杆菌对喹诺酮类药物的耐药率达57%~97%，亚胺培南则对阴性杆菌有较高的敏感覆盖率；耐甲氧西林葡萄球菌对环丙沙星、诺氟沙星、氯洁霉素、四环素、红霉素、头孢唑啉和氨苄西林的耐药率分别为40.9%、42.4%、63.6%、70.2%、85.9%、100.0%和100.0%；链球菌和肠球菌对多数β内酰胺类青霉素、氨基糖苷类、大环内酯类、四环素类以及磺胺类药物均呈高度耐药，耐药率在36%~100%。

Methods 102patients with Hp associated peptic ulcer were randomly divided into threegroups,groupA（n=98）receivedsanjiuweitai-basedquadrupleregimen（Yangweishul.2g,bid+ranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid）;group B（n=31）received colloidal bisˉmuth subcitrate110mg,bid+ranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid;groupC（n=23）receivedranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid.Antibiotics were griven for two weeks,the other drugs were given for six weeks,the efficacies were determined by gastroendoscopy or 13 C―UBT.

将102例胃镜证实为消化性溃疡者随机分为3组，A组48例给予养胃舒1.2g+雷尼替丁150mg+阿膜西林500mg+甲硝唑400mg，bid；B组31例给予铋剂220mg+雷尼替丁150mg+阿莫西林500mg+甲硝唑400mg，bid；对照组（C组，23例）给予雷尼替丁150mg+阿莫西林500mg+甲硝唑400mg，bid；以上药物除抗菌药物只服用2周外，其余药服至6周末疗程结束，第7周复查胃镜和 13 C呼气试验。

It was found that the light emission produced by the oxidation of luminol by postassium periodate in the basic medium was enhanced by ampicillin sodium. A new, simple and rapid method has been developed for the determination of ampicillin sodium.

在氢氧化钠介质中，高碘酸钾氧化鲁米诺产生化学发光，氨苄西林钠显著增强该体系的发光，据此建立了一种简单、快速测定氨苄西林钠的流动注射化学发光新方法。

Tween-80, which can improve the stability of Nitrofurazone Solution, can be used as solubilization of Nitrofurazone Solution.

吐温-80能增加呋喃西林的溶解度，用于呋喃西林溶液的制备能提高制剂稳定性。

Results: The 1034 strains of 8 types of pathogenetic aeromonase are sensitive to most of antibiotic and the highest resistance rate of 91.9% is ampicillin. The second one of 77.9% is piperacitlin and terramycin and sulfona mides are also with the high resistance rate of 62.4% and 56.9%. 127 strains (12.3%) which can produce the Ampc enzyme was found and 45 strains (4.4%) was multiple-drug resistance.

结果：8种1034株致病性气单胞菌对大多抗生素敏感，耐药率最高的是氨苄西林抗生素，达91.9%，哌拉西林次之，为77.9%，土霉素和磺胺类也有较高的耐药率，分别为62.4%和56.9%；检出具有产AmpC酶能力的致病性气单胞菌127株，占12.3%，多重耐药性菌株45株，占4.4%。

Methods: We collected 121 of clinical isolates of Enterobacter, including 87 isolates Enterobacter cloacae, 34 isolates Enterobacter aerogenes, all of the isolates were detected by cefoxitin three-dimension test, drug resistance phenotypes estimation, cloxacillin disc synergy test and cloxacillin-potentiated disc diffusion test respectively to find high-level AmpC β-lactamase isolates, drug resistance phenotypes estimation were also used to detected high induction producing AmpC β-lactamases isolates, meanwhile, we took three-dimension test as standard method, and compared to other methods, then calculated the coincidence rates, sensitivities and specificities of them.

采用头孢西丁三维实验、纸片耐药表型推断法、邻氯西林纸片协同法、双纸片邻氯西林增效试验分别检测高产AmpCβ-内酰胺酶株，获得高产AmpC酶在肠杆菌属细菌中的表达状况。采用纸片耐药表型推断法检测诱导和高产AmpC酶，同时以头孢西丁三维实验为标准，其他三种方法与之相比较，分析它们检测高产AmpC酶的符合率、灵敏度和特异性。

Among pathogens , the most common pathogens associated with VAP were Pseudomonas aeruginosa ( 3013 %), Acinetobacter baumanii (1115 %), Klebsiella pneumoniae ( 1017 %), Escherichia coli ( 716 %) and S taphylococcus aureus ( 618 %). Their multiple drug2resistance to antibiotics was serious. Drug sensitivity tests indicated that the GNB had lower drug2 resistance to such antibiotics as imipenem , amikacin , piperacillin/ tazobactam , ceftazidime , cefepime , cefoperazone/sulbactam , ciprofloxacin and ticarcillin/ clavulanate. Polymicrobial pathogens were more isolated in late2onset VAP than in early2onset VAP.

结果 共检出致病菌383 株，革兰阴性细菌占8411 %，其中非发菌占5114 %，肠杆菌科占3216 %，革兰阳性球菌占1218 %，其中MRSA和MRSE 占615 %，真菌占311 %；前5 位致病菌分别为铜绿假单胞菌(3013 %)、鲍氏不动杆菌(1115 %)、肺炎克雷伯菌(1017 %)、大肠埃希菌(716 %)、金黄色葡萄球菌(618 %)等；药敏结果显示这几类菌株的多重耐药现象严重，较为敏感的抗菌药物有亚胺培南/西司他丁、阿米卡星、哌拉西林/他唑巴坦、头孢他啶、头孢吡肟、头孢哌酮/舒巴坦、环丙沙星及替卡西林/克拉维酸等，革兰阳性细菌均对万古霉素敏感；迟发性VAP 的混合培养比例显著高于早发性VAP。

Pharmacology function 】the anti-virus table of this article with anti-virus activity and ammonia Xia west wood likeness, because of it at absorb of unit animal ratio ammonia Xia west Lin2 Hao3, blood medicine density Gao, is an ammonia Xia west wood of 300% above, past to whole body sexy dye of the curative effect be better.

本品的抗菌谱与抗菌活性与氨苄西林相似，由于其在单位动物的吸收比氨苄西林好，血药浓度高，是氨苄西林的3倍以上，故对全身性感染的疗效较好。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。