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We have investigated whether the combination of decitabine and a clinically relevant inhibitor of histone deacetylase activity (belinostat, PXD101) can further increase the re-expression of genes epigenetically silenced by DNA methylation and enhance chemo-sensitisation in vivo at well-tolerated doses.

我们研究了地西他滨联合组蛋白去乙酰化酶抑制剂(belinostat,PXD101)是否可以进一步增加DNA甲基化后生沉默基因的重新表达,在耐受性良好的剂量下增加化疗敏感性。

Objective To evalue the efficacy and side effects of Paclitaxeland Gemcitabinerespectively combined with cisplatin on advanced nonsmall-cell lung cancer.

目的 评价紫杉醇与顺铂及吉西他滨与顺铂联合治疗晚期非小细胞肺癌的疗效及毒副反应。

The invention also encompasses a pharmaceutical composition that is comprised of an EGFR kinase inhibitor and gemcitabine combination in combination with a pharmaceutically acceptable carrier.

本发明还涵盖药物组合物,其包含EGFR激酶抑制剂和吉西他滨组合,结合以药用载体。

Objective To evaluate the efficacy and side effects of domestic gemcitabine and cisplatin in the treatment of retreatment non-small cell lung cancer.

目的评价国产吉西他滨联合顺铂治疗晚期复治非小细胞肺癌的疗效和毒副反应。

Among these results,expression patterns of 21 genes were consistent with those in the microarray data.3.3 Emodin potentiates growth inhibition induced by gemeitabine in pancreatic cancer cells in vitroTo investigate the effect of ernodinon cell viability,pancreatic cancer cell lines (Pane-1,Mia Paca-2 and Bxpc-3) were treated with increasing concentrations of emodin (0-160μM) for 24,48 and 72 hours.

结果显示21个基因两种方法所得基因表达倍数大致相当。3.3 Emodin在体外增加吉西他滨对胰腺癌细胞生长的抑制为了探讨Emodin对胰腺癌细胞生长的影响,应用MTT方法检测不同浓度的Emodin(0-160μM)作用于胰腺癌细胞24h、48h和72h的效应。

Objective To compare the efficacy and toxicities of three regimens in the treatment of advanced non-small cell lung cancer.

目的比较顺铂分别联合紫杉醇,吉西他滨,长春瑞滨治疗晚期非小细胞肺癌的近期疗效和毒副反应。

Objective: To study the efficacy and side reactions of gemcitabine combined with cisplatin in the treatment of advanced liver cancer.

目的:了解吉西他滨联合顺铂治疗晚期肝癌的疗效与不良反应。

Objective To observe the efficacy, toxicity of gemcitabine and cisplatin regimen in advanced non-small-cell lung cancer.

目的观察吉西他滨与顺铂方案治疗晚期非小细胞肺癌的临床疗效、毒副作用。

Cisplatin plus gemcitabine is an appropriate option for the treatment of patients with advanced biliary cancer.

顺铂加吉西他滨是晚期胆道癌病人的一种恰当的治疗选择。

Objective To evaluate the efficacy and toxicity of the combination of gemcitabine and cisplatin in the treatment of patients with advanced non-small cell lung cancer.

目的 观察吉西他滨联合顺铂治疗晚期非小细胞肺癌的疗效和毒副反应。

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