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We have investigated whether the combination of decitabine and a clinically relevant inhibitor of histone deacetylase activity (belinostat, PXD101) can further increase the re-expression of genes epigenetically silenced by DNA methylation and enhance chemo-sensitisation in vivo at well-tolerated doses.

我们研究了地西他滨联合组蛋白去乙酰化酶抑制剂(belinostat,PXD101)是否可以进一步增加DNA甲基化后生沉默基因的重新表达,在耐受性良好的剂量下增加化疗敏感性。

Mrs. Linton took off the grey cloak of the dairy-maid which we had borrowed for our excursion, shaking her head and expostulating with her, I suppose: she was a young lady, and they made a distinction between her treatment and mine.

如果凯西想回来而他们不让她出来的话,我就把他们这豪华大窗的玻璃砸成一百万块碎片。她安静地坐在沙发上。林顿太太一边帮她脱下了我们为远足从挤奶女工那借来的斗篷,一边摇着头告诫她。

Now a Genin, Naruto is part of a three-man team - the members are Naruto, Sasuke, Sakura, and their instructor, Kakashi.

现在终于成为下忍的鸣人跟小樱和佐助被分配到了同一个三人组里面,他们的老师是卡卡西。

Through calculating and analyzing the monitoring data, the moisture transfer and form disciplinarian in the hugely thick aeration zone are posted under the flood irrigation, and the water amount of irrigative water that returned to supply the groundwater is calculated, then verify it using the Darcy formula.

通过对监测数据的计算和分析,揭示了大水漫灌条件下,灌溉水在包气带中湿润峰和零通量面的运移和形成规律,计算了灌溉水回归补给地下水的水量,并利用达西公式进行验证。

From the isohyetal maps, we can display the spatial distribution of rainfall caused by typhoons in Nan Shih Creek watershed.

由等雨量线图显示,南势溪集水区台风降雨之分布分别由东向西以及南向北之方向递减;台风降雨中心多发生於福山雨量站所在之区域,降雨量则由福山雨量站向东朝下盆雨量站方向递减;另外,位於本区北端之大桶山雨量所处之区域,则是另一处发生明显降雨空间变化的地区,故台风降雨在南势溪集水区内的分布具有空间变异之特性。

The directions of vertical movement of the crust and that of isostatic adjustment are opposite.

同时还显示出西准噶尔与准噶尔盆地在统一的挤压构造作用下,有不同的响应。

Two months after Lawton's transfer, Chelsea spent just over half of the British record £20,000 they had received on a new striker.

劳顿转会之后,切尔西花了超过英国球员转会记录20,000英磅的一半价格买下了一个新的前锋。

Then Simon Peter, having a sword, drew it, and struck the servant of the high priest, and cut off his right ear. And the name of the servant was Malchus.

西满伯多禄有一把剑,就拔出来,向大司祭的一个仆人砍去,削下了他的右耳;那仆人名叫玛耳曷。

Then Simon Peter, who had a sword, drew it, struck the high priest's slave, and cut off his right ear. The slave's name was Malchus.

西满伯多禄有一把剑,就拔出来,向大司祭的一个仆人砍去,削下了他的右耳;那仆人名叫玛耳曷。

Three groups of patients received different interventions under the prerequisites of routine medications including blood-activating and stasis-eliminating, neurotrophy, and vasodilator patients of nitric ether group received oral administration of isosorbide dinitrate or glycerin trinitrate; patients of calcium antagonist group received oral administration of Sibelium or Novarsc; and patients of no specific medication group did not receive any preventive medicine.

对192例行高压氧治疗的3组患者在常规使用活血化瘀、神经营养、血管扩张剂等药物的前提下,硝酸酯类组口服消心痛或硝酸甘油,钙拮抗剂组口服西比灵或络活喜等,未特殊用药组则没有预防性使用药物。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力