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Methods Using PCE micronuclear test, Chinese hamster lung cell chromosome aberration experiment and rat teratogenicity, to observe the toxicity of free MMC and the MMC absorbed onto ACNP on heredity and reproduction.

目的 检测纳米活性炭对丝裂霉素的遗传毒理及生殖毒理学效应的影响方法采用小鼠骨髓嗜染红细胞微核试验、中国仓鼠肺细胞染色体畸变试验及致畸试验对受试物ACNP-MMC进行遗传毒性及致畸性检测。

We examined the response of human cord blood CD34+ cells to a specific mitotic signal in io.

我们通过动物体内实验检测人脐血CD34+细胞对特异丝裂信号的反应。

The results suggest that the antioxidant compounds present in Morinda citrifolia plant may contribute to the anti-EBV activies.

证明了海巴戟天萃取物的抗氧化成分与抗 EB 病毒的活性有相互的关系,也了解可能经由抑制 EB 病毒溶裂基因的转录或抑制细胞中 ATF-2 的表现而达到抗病毒的效果。

In this study, the effects of STH and insulin on porcine in vitro oocyte maturation and cleavage after parthenogenetic activation were investigated.

研究了生长激素、胰岛素单独或者联合作用对猪卵母细胞体外成熟及孤雌激活后卵裂的影响。

The article reported the effect of exogenous Ca 2+ on the proliferation of Saccharomyces cerevisiae and Schizosaccharomyces pombe .

SD培养基中外加不同浓度的Ca2 +可促进酿酒酵母与粟酒裂殖酵母细胞的增殖,但在促进增殖方式上存在明显差异。

In order to understand the function of this gene within short time, we also constructed yeast (Schizosaccharomyces pombe vector to analyze the gene function, but the result investigated that over expression of this gene could not increase the length of yeast cell. It suggested that expression of the gene is not a direct reason in cell elongation.

为了在短时间内初步研究该基因的功能,构建了酵母表达载体,利用裂殖酵母表达系统对该基因的功能进行活体分析,没有发现该基因对单核的酵母细胞的伸长有明显影响。

In this study, we utilized the S. pombe to explore the effect of dosage-dependent of edelfosine inhibiting the growth, cell division and nucleus division of S.

而以粟酒裂殖酵母作为研究对象,易于进行细胞学操作、具有明显的细胞周期,且生长迅速、易于培养。

In model organism fission yeast,Schizosaccharomyces pombe,100-200 rDNA gene copies are located on both left and right ends of chromosomeⅢ.The integrity of rDNA is critical for cell growth and survival.

在模式生物裂殖酵母(fission yeast,Schizosaccharomyces pombe)基因组中,100-200拷贝的rDNA基因分布在Ⅲ号染色体左右两端的末端附近。rDNA区的完整性对于细胞生长和存活是至关重要的。

Results The bletilla colloid was a homogenous viscous colloid whose relative viscosity was 2324.6 mm2/s. It was easily injected through 4-F catheter and hyperattenuating under fluoroscopy, meanwhile, with good histocompatibility and hemo-compatibility, without pyrogenetic response and toxicity. In vitro, the mixture of bletilla colloid and MMC did not produce separation and suspention phenomena but released 50%of MMC at 1.8h and 100%at 3.4h. The bletilla colloid mainly embolized peripheral arteries, maintaining occlusion for 5 weeks and without formation of collateral circulation. The injuries of normal hepatic tissues were slight, without hepatic cytonecrosis.

结果 (1)白芨胶为一种均质的胶状物,有一定粘滞性,相对粘度2 324.6 mm2/s,不透X线,易经4F导管注射;(2)白芨胶具有良好的血液相容性和组织相容性,无致热原性及毒性作用;(3)白芨胶-丝裂霉素C体外混合后,无分层及悬浮现象,释放MMC 50%约需1.8小时,100%需3.4小时;(4)白芨胶主要栓塞末梢小动脉,栓塞牢靠,维持时间可达5周,不易形成侧支循环;(5)白芨胶栓塞对正常肝组织损伤轻微,未出现肝细胞坏死。

Firstly, the parallel growth inhibition experiment of S. pombe wild-type cells, spm1△, pmp1△, mid2△and relevant retransform strains were carried out in order to farther confirmed the effect of edelfosine on spm1, pmp1 and mid2 genes.

因此,本实验的目的是探讨依地福新对经Mid2介导的,Pmp1抑制的MAPK Spm1信号通路的影响,以阐明依地福新抑制粟酒裂殖酵母细胞胞质分裂的作用机制。

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