被抑制的

Anorectic effects of GLP-1 are most apparent when the peptide is administered directly into the central nervous system, but suppression of food intake has also been noted in some cases with peripheral administration.

研究显示，GLP抑制食欲的作用在GLP-1被注射到中枢神经系统的时候是最明显的，但是外周摄取GLP-1也能起到抑制食欲效果。

Methylation of CpG islands in the promoters induces gene silencing. The multiple tumor suppressor gene P16, located at chromosome 9p21, regulating normal proliferation of cells with a functional unit constituting of p16, cyclin D1 and pRb together. Methylation of P16 gene has been detected in several lymphocytic and plasmacytic malignancies such as lymphoma, acute lymphocytic leukemia and multiple myeloma and shows relationships with the pathogenesis of these diseases. Application of demethylation agents or arsenical to refresh the gene functions will be expected to be a new treatment for hemopoietic malignancies.

基因启动子区CpG岛甲基化常导致基因沉默。P16基因是一定位于9p21的多种肿瘤抑制基因，通过pl6INK4Acyclin D1-PRb通路维持机体细胞的有序增殖。P16基因甲基化在淋巴瘤、急性淋巴细胞性白血病、多发性骨髓瘤等多种淋巴细胞浆细胞肿瘤中被检测到，并与疾病的发生、发展存在一定关系，应用甲基化抑制因子或砷剂去甲基化治疗，恢复基因功能可望成为血液恶性肿瘤治疗的一种新手段。

Previously, consideration was given to the ability of AA to inhibit cancer metastasis by increasing collagen synthesis and inhibiting the activity of hyaluronidase front cancer cells.

过去维他命C抗癌的机转被认为与其能促进胶原蛋白的产生及抑制癌细胞产生玻尿酸酵素的活性以抑制癌细胞的转移有关。

As a result, there are no specific advantages of processing signals in frequency domain, and we propose to directly process signals in time domain. By this way, it is observed that in time domain the signal signatures can be arranged into groups of orthogonal components, leading to a very natural group-wise symbol recovery scheme. To realize this figure of merit, we propose a GSC-based receiver, which also takes into account the mitigation of channel mismatch effects caused by the channel temporal variation and the imperfect estimation.

因此，吾人提出直接於时域中处理讯号，於时域中，吾人发现讯号特徵矩阵能够被分为数个拥有正交元素的群组，能自然地被用来设计群组式讯号侦测技术，为了实现此特性吾人提出一个GSC接收机，其能同时抑制通道时间变化与通道估计错误所产生之通道偏差效应。

In 5 μM. pseudolaric acid B-treated HeLa cells, caspase-3 proenzyme decreased followed by the degradation of caspase-3 substrates, ICAD (inhibitor of caspase dependent DNase) and PARP poly-(ADP-ribose polymerase.

土槿皮乙酸5μM作用于HeLa细胞后，caspase-3的酶原被降解，caspase-3底物ICAD(inhibitor of caspase activated DNase)和PARPpoly-(ADP-ribosepolymerase降解，caspase-3的抑制剂可部分抑制土槿皮乙酸诱导的细胞死亡，表明土槿皮乙酸诱导HeLa细胞凋亡时激活了caspase-3。

Inhibition to activated sludge process by 2-naphthol was also investigated by Warburg respirometer to verify the conclusion drawn from Rank Cell respirometer test. 2-Naphthol in low concentration was biodegradable, hence resulted in the acceleration of respiration, while in higher concentration 2-naphthol would dramatically inhibit microorganisms respiration on account of high K〓 and electron density.

用Warburg呼吸仪研究了2-萘酚对活性污泥过程的抑制作用，验证了RankCell呼吸仪的研究结论，发现低浓度下2-萘酚自身能被生物降解而使活性污泥中微生物呼吸速率升高；浓度增加后2-萘酚因良好的脂溶性和强亲核能力而对活性污泥过程产生强抑制。

Mg/ kg way partially inhibited by L- NAME,or by sodium orthovanadate(50 ug/ kg),a potent inhibitor of protein tyrosine phosphatase;(2)genistein also decreased the PP of renal vascular bed in a dose-dependent manner and the effect of genistein was completely inhibiteby pretreatment with sodium orthovanadate,but unaffected by L- NAME;and(3 genistein decreased the PP of mesenteric vascula bed in a dose-dependent manner,an effect which was partially inhibited by sodium orthovanadate,but unaffected by L- NAME .

mg/ kg引起的效应；(2)向肾血管灌注环路中直接注射GST也可剂量依赖性地降低肾动脉的灌流压，预先注射正钒酸钠可完全抑制GST引起的效应，而L- NAME对此效应没有影响；(3)肠系膜血管灌流环路中注射GST可剂量依赖性地降低其灌流压，这一效应可被正钒酸钠部分抑制，而L- NAME对此无影响。

Result vitamin A and 4HPR fall to Hela cell collect form have apparent inhibition, can restrain Hela cell to be opposite the action causing tumor of naked rat (the curb tumour action of P.01); vitamin A issues visible cell solid by force to shrink at 4HPR(P.01); report lens, nuclear film is screwy, nuclear chromosome gathers agglomerate stand by the wither such as nuclear film to die DNA of cell of cellular feature; by degradation, a collection of illustrative plates of typical " of shape of " a flight of stairs appears in electrophoresis of agaragar candy gel.

结果维生素A和4HPR对Hela细胞集落形成有明显抑制功能，并可抑制Hela细胞对裸鼠的致瘤功能(P.01)；维生素A的抑瘤功能强于4HPR(P.01)；电镜下可见细胞固缩，核膜扭曲，核染色体聚集成块并靠近核膜等凋亡细胞特征；细胞DNA被降解，在琼脂糖凝胶电泳中呈现典型的&阶梯状&图谱。

Hexokinse is inhibited by glucose 6-phosphate which builds up after PFKis inhibited.Pyruvate kinase is activated by fructose 1,6-bisphosphate but allosterically inhibited by ATP and alanine. Like PFK,it is also regulated hormonally by glucagon.

己糖既没被 PFK 受到抑制后积累的葡萄糖 6-磷酸激活，但受到 ATP 和丙氨酸的别构抑制；像 PFK 一样，它也受到胰高血糖素的调节。

And the result finds that HDAC-2 is higher expression and harder to be repressed in the OSF than in the NOM.

换言之，OSF纤维母细胞比正常者有更高HDAC-2的表现且不易被HDAC-2的抑制剂所抑制。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。