被抑制的

Rat glioma cell C6 was infected by the deficiency recombinant retrovirus (named C6TK). The sensitivity of C6TK cells to GCV or ACV increased 450 or 10 times than that of C6 cells respectively. Rat C6 glioma model was successfully built, and SD rats inoculated intracerebrally C6TK cells had normal gliomas. The average survival periods of the rats were about 15 days. However, after treated with ACV, the growth of C6TK tumors obviously regressed, and the survival periods extended to 57.8±8.1 days, especially in rats injected with mixed PA317TK and C6 cells or in situ PA317TK cells, which the tumors nearly disappeared after ACV administration and the survival periods extended to over 120 or 71.4±36.1 days respectively, P＜0.001.

结果：构建了带有HSV-tk基因的反转录病毒载体GINaTK，应用脂质体转移方法将GINaTK导入反转录病毒包装细胞PA317，成为产病毒细胞PA317TK，用带有HSV-tk基因的复制缺陷型反转录病毒感染C6细胞，命名为C6TK细胞，对GCV和ACV的敏感性分别高于亲本450倍和10倍；成功地建立了大鼠脑胶质瘤模型，并证实转染细胞C6TK的成瘤效应未改变，存活期约为15天；而经ACV治疗后，含有C6TK细胞的肿瘤生长明显被抑制，大鼠生存期延长为57.8±8.07天，尤其是采用PA317TK细胞混和治疗组和原位治疗组，肿瘤基本消失，大鼠生存期显著延长，混和治疗组存活120天以上，原位治疗组存活至71.4±36.1天。t检验，P值均小于0.001。

Results: GINaTK retroviral vector containing HSV-tk was constructed and transduced into PA317 retrovirus packaging cell by lipofectin (named PA317TK). Rat glioma cell C6 was infected by the deficiency recombinant retrovirus (named C6TK). The sensitivity of C6TK cells to GCV or ACV increased 450 or 10 times than that of C6 cells respectively. Rat C6 glioma model was successfully built, and SD rats inoculated intracerebrally C6TK cells had normal gliomas. The average survival periods of the rats were about 15 days. However, after treated with ACV, the growth of C6TK tumors obviously regressed, and the survival periods extended to 57.8±8.1 days, especially in rats injected with mixed PA317TK and C6 cells or in situ PA317TK cells, which the tumors nearly disappeared after ACV administration and the survival periods extended to over 120 or 71.4±36.1 days respectively, P ＜0.001.

结果：构建了带有HSV-tk基因的反转录病毒载体GINaTK，应用脂质体转移方法将GINaTK导入反转录病毒包装细胞PA317，成为产病毒细胞PA317TK，用带有HSV-tk基因的复制缺陷型反转录病毒感染C6细胞，命名为C6TK细胞，对GCV和ACV的敏感性分别高于亲本450倍和10倍；成功地建立了大鼠脑胶质瘤模型，并证实转染细胞C6TK的成瘤效应未改变，存活期约为15天；而经ACV治疗后，含有C6TK细胞的肿瘤生长明显被抑制，大鼠生存期延长为57.8±8.07天，尤其是采用PA317TK细胞混和治疗组和原位治疗组，肿瘤基本消失，大鼠生存期显著延长，混和治疗组存活120天以上，原位治疗组存活至71.4±36.1天。t检验，P值均小于0.001。

Implementing good solid phase control, giving full play to peridium inhibitability of polymerized substance driven well fluid, keeping good rheologicability, sand carrying ability are considered to satisfy the requirement under well, reduce drilling resisting exte...

认为：在目前尚无更适合该地区新型钻井液体系的情况下，只要很好的实现固相控制，充分发挥聚合物钻井液的包被抑制性，保证钻井液具有良好的流变性、携砂性和滤失造壁性，也能较好地满足井下要求，降低阻卡程度，减少井内事故。

The optical properties, fluorescence quantum yields and electrochemical properties of these polymers were investigated. It was found that the optical properties of the polymers did not show obvious dependence on the alkyl length on phenylene.

苯环上烷基侧链长度的改变对取代共聚物的光谱、电化学和发光效率等影响很小；而随着苯环上烷氧基侧链长度的增加，聚合物的光谱稳定性逐渐增强，荧光发射光谱中的0-1转变逐渐被抑制，荧光发射半峰宽减小。

By projecting signals with different frequencies into the subspace I, the signal with the supply frequency has the maximum value. Consequently, in the spectrum of the reciprocal of the projecting value, the supply frequency component is cut off and the fault feature component emerges in the spectrum.

把不同频率的信号投影到子空间I，基频信号在该空间的投影将远大于其他的频率分量，因此在投影的倒数谱中，基频分量被抑制，凸显出了故障频率分量。

Rapid eye movement sleep consists of a dreaming state in which there is activation of the cortical and hippocampal electroencephalogram, rapid eye movements, and loss of muscle tone. Although REM sleep was discovered more than 50 years ago, the neuronal circuits responsible for switching between REM and non-REM sleep remain poorly understood. Here we propose a brainstem flip-flop switch, consisting of mutually inhibitory REM-off and REM-on areas in the mesopontine tegmentum. Each side contains GABA (gamma-aminobutyric acid)-ergic neurons that heavily innervate the other.

快动眼睡眠是一个包括有皮层和海马脑电活动的睡梦状态，可见眼球的快速运动和肌张力减低，尽管快动眼睡眠已经被发现50余年了，对其与非快动眼睡眠之间的神经回路却知之甚少，我们用脑干触发转换器，包括脑桥背盖区一个互相抑制的快动眼-关、快动眼-开区域，每侧均包含高度互相支配gamma氨基丁酸能神经元。

Distant effect of Jurassic collisions of Qiangtang terrane,Lasa terrane and Paleo\|Pacific land onto the Eurasian land made East Qinling\|Dabie Mountains in a compressional circumstance for a long time,and suppressed its orogenic extension;whereas,Cretaceous late\|collisional extension and appearance of West Pacific trench\|arc\|basin system relieved East Qinling\|Dabie Mountains of external compression,instantly result in violent orogenic lithosphere delamination\|extension and depressurized\|calefactive melting,and consequently,led to the formation of large scale Early Cretaceous granitoids and intermediate\|acidic volcanic rocks.

羌塘地体、拉萨地体和西太平洋古陆在侏罗纪与欧亚大陆拼贴碰撞的远距离效应使东秦岭-大别造山带长期处于挤压环境，伸展作用被抑制；白垩纪的碰撞晚期伸展和西太平洋沟弧盆体系的远距离效应使东秦岭-大别地区的外部挤压消失，导致造山带岩石圈迅速强烈拆沉伸展和减压增温熔融，从而形成大规模早白垩世花岗岩类和中酸性火山岩。

The results are as follows.(1) Long train electrical stimulation at the dMNF facilitated myoelectric activities of genioglossus and phrenic muscle.(2) Short train electrical stimulation of dMNF, when delivered in the inspiratory phase, caused prolongation of myoelectric activities of genioglossus and phrenic muscle; but when delivered in the expiratory phase, myoelectric activities of genioglossus and phrenic muscle were shortened.(3) Long train electrical stimulation at the vMNF inhibited myoelectric activities of genioglossus and phrenic muscle.(4) Short train electrical stimulation of vMNF caused shortening of myoelectric activities of genioglossus and phrenic muscle, when delivered in the inspiratory phase, but a prolongation when delivered in the expiratory phase.(5) The effects of microinjection of glutamate to dMNF and vMNF were similar to those of electrical stimulation.

结果如下：(1)长串电脉冲刺激dMNF引起颏舌肌和膈肌肌电活动明显增强；(2)短串电脉冲刺激dMNF，当刺激落位于吸气相时，引起颏舌肌和膈肌在吸气相的肌电活动延长，当刺激落位于呼气相时，引起颏舌肌和膈肌在呼气相的肌电活动提前终止；(3)长串电脉冲刺激vMNF使颏舌肌和膈肌肌电活动明显被抑制；(4)短串电脉冲刺激vMNF，当刺激落位于吸气相时，引起颏舌肌和膈肌在吸气相的肌电活动提前终止，当刺激落位于呼气相时，引起颏舌肌和膈肌在呼气相的肌电活动延长；(5)在dMNF和vMNF分别微量注射谷氨酸钠，其效应与电刺激结果基本一致。

If do not have reliable contraceptive measure, gravid itself is opposite one kind namely sexual low-key process, the harmony of sexual life of husband and wife often is destroyed by gravid scared psychology.

如果没有可靠的避孕措施，妊娠本身就是一种对性抑制的过程，夫妻性生活的和谐常被妊娠的恐惧心理破坏。

The role of DDAH is to break down modified amino acids Asymmetric dimethylarginine (ADMA and monomethyl arginine that are produced by the body and have been shown to inhibit NO synthase.

DDAH的作用是破坏由体内产生的被修饰的氨基酸（不对称的二甲基精氨酸和一甲基精氨酸）并已证实它可以抑制NO的合成。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。