被抑制

In the electrophysiological study in vivo, it was observed that the weak EA could depress the nociceptive responses of spinal dorsal horn neu- rones, which might be blocked by P1—purinergic receptor antagonists.

在横断脊髓的大鼠上用电生理学方法进一步观察到，弱电针也可抑制髓背角广动力型神经元的伤害性反应，弱电针的这种效应也可被腺苷受体阻断剂所阻断，说明嘌呤类在脊髓水平参与弱电针镇痛。

Wheat Rht genes encode growth repressors and their functions could be normally suppressed by GA.

小麦Rht基因编码生长阻遏物，其功能可被GA所抑制。

In mammals the Notch gene family comprise four related genes, Notch1-4, as the Notch ligands that encode transmembrane proteins. Ligand-receptor interaction mediated Notch activation ultimately leads to the conversion of effectors-CSL CBF1, Su(H, Lag-1 proteins, from repressors to transcriptional activators, and subsequent up-regulation of downstream targets.

在哺乳动物中，Notch基因家族包含了4个相关的基因，分别为Notch-1至-4，和Notch受质蛋白一样能被转译成膜蛋白；受质-受体间相互作用所引起Notch受体蛋白的活化会促使作用蛋白-CSL CBF1， Su(H， Lag-1 蛋白扮演抑制分子或者是转录活化分子上的角色改变，并且进一步地正向调节下游的标的基因。

In the mixed solvent of dimethyl phthalate / TBP or phenyl ether / TBP, the selectivity for styrene oxide is good but the conversion of styrene is low due to the coordination to the catalyst of the solvent.

邻苯二甲酸二甲酯或二苯醚等与磷酸三丁酯的混合溶剂中环氧化的选择性较高，但由于溶剂对催化剂的配位作用抑制了催化剂的活性，苯乙烯转化率很低；当部分的邻苯二甲酸二甲酯或二苯醚被甲苯取代后，苯乙烯的转化率提高，生成环氧苯乙烷的选择性不变。

In this thesis, this system is used for epoxidation of propylene and styrenewith good results. The solvent effect is investigated for epoxidation of styrene. In the mixedsolvent of dimethyl phthalate / TBP or phenyl ether / TBP, the selectivity for styreneoxide is good but the conversion of styrene is low due to the coordination to thecatalyst of the solvent. When part of dimethyl phthalate or phenyl ether is replacedby toluene, the conversion increases and the selectivity keeps constant.

邻苯二甲酸二甲酯或二苯醚等与磷酸三丁酯的混合溶剂中环氧化的选择性较高，但由于溶剂对催化剂的配位作用抑制了催化剂的活性，苯乙烯转化率很低；当部分的邻苯二甲酸二甲酯或二苯醚被甲苯取代后，苯乙烯的转化率提高，生成环氧苯乙烷的选择性不变。

MMPs are usually secreted as latent, inactive proenzymes, which need to be activated (Fig 1 ), and/or are bound to their native inhibitors, the tissue inhibitors of metalloproteinases.8 Activation may involve proteolysis and/or oxidation of the latent enzyme.8 Proteolytic activation of the proenzymes cleaves the propeptide sequence, which masks the active site of the latent enzyme.

金属蛋白酶常以无活性的酶原方式分泌，而后者要么需要被激活要么与附近的或组织中金属蛋白酶抑制物结合。激活作用包括了具有潜在酶的蛋白水解作用或氧化作用。酶原的蛋白水解激活作用能将掩盖活性部位的潜在酶的前肽序列破坏。

Can reverse JA-induced migration inhibition JA-treated cells also showed significantly higher adhesion to laminin In conclusion these results indicate a novel anti-tumor role of JA via reducing reorganization of cytoskeleton increasing integrin 3 expression and adhesion ability to inhibit tumor cells migration Furthermore immunofluorescence staining of phalloidin/actin indicated that JA-treated cells exhibited cytoskeleton rearrangement and significant decreases in the number and length of filopodia Activity of Rho-family small GTPases was detected by a GST-pull down assay and showed that GTP-loaded Cdc42 and Rac were decreased in JA-treated cells In the future we hope these findings will be helpful to further understand the mechanisms underlying tumor progression in oral cancer and subsequently improve the cancer prevention and treatment

以抗体阻断integrin ？3可以有效使OC2恢复被JA所抑制的迁移能力。细胞贴附实验指出JA能提高OC-2在laminin环境下的贴附能力。当我们进一步以免疫萤光染色观察细胞，发现在JA处理下的OC-2，其外形、细胞骨架和细胞边缘的filopodia的密度和长度明显减少，利用GST-pull down assay侦测到Cdc42-GTP和Rac-GTP的表现量降低。推论爵床素A可能透过刺激口腔癌细胞大量表现integrin ？3，使细胞贴附能力增加或是透过改变细胞骨架来降低细胞迁移能力。希望本研究对於JA所做的抗癌及抗转移效应评估能提供口腔癌治疗在研发上一些帮助。

PARP inhibition may prove beneficial for the treatment of atherosclerosis.

PARP抑制可能会被证实对动脉粥样硬化的治疗有帮助。

All Gram-negative species were also mupirocin-resistant, but inhibited by neomycin and/or polymyxin B components of TAO.

所有的革兰氏阴性菌对莫匹罗星都有耐药性，但被TAO中的新霉素和/或多粘菌素B组分所抑制。

But this gut worm doesn't slow them down. In fact, infected shrimp eat 30 percent more prey than those that are parasite-free.

而这些寄生虫不但没有抑制寄主们生长，反而让寄主们胃口大开，要比未被寄生多吃30%。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。