衰竭

The FDA did not relabel Ketek to indicate its possible severe hepatotoxicity until 16 months after the first liver-failure cases became public.

直到第一例肝衰竭病例公开后的16个月，FDA才重新在Ketek的标签中注明其可能具有严重肝毒性。

The FDA did not relabel Ketek to indicate its possible seere hepatotoxicity until 16 months after the first lier-failure cases became public. The withdrawal of approal for two indications, acute bacterial sinusitis and acute exacerbation of chronic bronchitis, for which Ketek's efficacy had neer been demonstrated, did not occur until February 12, 2007 — only a day before the Congressional hearing on Ketek.

FDA一直到一例肝脏衰竭事件曝光16个月后才对Ketek重新标上可能引起严重的肝毒性。2007年2月12号，也就是议会对Ketek进行听证的前一天，FDA才撤消批准Ketek用于治疗急性细菌性鼻窦炎以及慢性支气管炎的急性加速期―――从来都没有证据显示Ketek对治疗这两种病有效。

You were rightabout the liver failure.

关于肝功能衰竭，你是对的

Results: thirty cases were cured and 7 cases were improved, accounting for 83% and 13.7% respectively; 8 cases gave up treatment, accounting for 15.7%; 6 cases died, accounting for 11.8%.of the 6 died infants, 5 cases died of respiratory failure and pulmonary hemorrhage; 3 cases were sclerema neonatorum, 3 cases were very low birth weight infants; 3 cases' gestational age was less than 32 weeks, 1 case had intrauterine growth retardation, 1 case had asphyxia history of birth, 1 case had infection history , 1 case had convulsion history (suspected intracranial hemorrhage).

结果：治愈30例，占58.8％；好转7例，占13.7％；自动出院8例，占15.7％；死亡6例，占11.8％，其中5例死于呼吸衰竭，肺出血。其中3例有硬肿症，3例为极低体重儿；孕周2周者3例；1例有宫内发育迟缓，1例有新生儿窒息史，1例有感染史，1例有抽搐史。

Results 3 patients suffering bronchopleural fistula were all cured and 13 of 16 patients of anastomses leakage were cured, with a rate of 81.25%, the average hospital time was 46 days, one patient died of bleeding and one died of lung infection, the other gave up therapy and discharged selfly.

结果 3例支气管胸膜瘘患者全部治愈，16例胸内吻合口瘘患者治愈13例，治愈率为81.25%，平均住院日为46天，1例治疗中死于大呕血，1例死于肺部感染、呼吸循环衰竭，另1例放弃治疗出院。

Glucocorticoid: For early skin swelling and serositis, myositis, interstitial lung inflammation, and so effective, and for vascular damage and fibrosis invalid, side effects of high-dose applications, especially for the existing kidney damage Patients easily add vascular damage, and even cause acute renal failure, it is necessary to be careful when using the dosage and the treatment should be individualized, based on clinical performance.

糖皮质激素：对于早期皮肤的肿胀及浆膜炎、肌炎、肺间质炎症等有效，而对于血管损害和组织纤维化无效，大剂量应用时副作用大，尤其是对于已有肾脏损害的患者易加重血管损害，甚至引起急性肾功能衰竭，故使用时须慎重，使用剂量及疗程应个体化，依据临床表现而定。

Patients who accompanied the acute respiratory failure accepted the ventilator, NPPV, or PSV+PEEP ventilation, and they recoveried soonly.

8病人伴急性呼吸衰竭接受呼吸器，创正压，或+ PSV的窥视通风，他们治愈出院soonly 。

Systemic hemodynamic failure inevitably alters splanchnic blood flow but in an unpredictable way.

全身血液动力学衰竭必然通过不可预知的方式改变内脏血流量。

Pathological observations showed that the bone marrow and spleen of non-treated IMAA mice demonstrated typical aplastic anemia pattern, including bone marrow failure, marked splenatrophy, but the bone marrow and lymphoid tissues in the IMAA mice of irradiation-treated group were recovered to normal at day 28 after treatment.

结果表明：①IMAA组小鼠活存率为12.5%，平均存活时间为27.4 13.4天，照射治疗组活存率为100%，平均存活时间60天以上，单纯照射组无死亡；②外周血白细胞数：IMAA组呈进行性下降，直至死亡，照射治疗组第10天与免疫再障组相似，以后开始缓慢回升，基本上达到治疗前水平；③红细胞比容：未治疗IMAA组于14天后呈进行性降低，至第35天比实验前减低2/3，照射治疗组与单纯照射组一样，第14天有轻度减低随后升高，至35天接近正常；④骨髓有核细胞数：IMAA组呈进行性减低，无恢复趋势，照射治疗组于一过性减低后迅速增加，第28天达到正常水平；⑤骨髓和淋巴组织病理形态观察：IMAA组小鼠呈典型再生障碍性贫血病理改变，骨髓造血衰竭，脾脏明显萎缩，而照射治疗组于第28天骨髓和脾淋巴脏组织基本上恢复正常。

In their practice,they attached importance to nurse s mastery of respirator s function,management of respiratory tract,correct methods and right time for sput um drainage as well as the intensive care of cardiovascular and renal functions.

笔者介绍30例重症胰腺炎合并多器官功能衰竭患者的监护要点。在神经内科常规护理的基础上，对 36例重症脑卒中患者中的 14例施行监护，另 2 2例作为对照。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。