衰竭

Of the 60 patients, chronic nephritis 27 cases,acute serious nephritis 3 cases,essential hypertension 9 cases,diabetes 9 cases, multilocular cyst 6 cases,lupus nephritis 6 cases were enrolled. 60 CRF cases with four phase,including the phase of compensation of renal malfunction,the phase of no-compensation of renal insufficiency the phase of azotemia and the phase of renal failure,were divided into three groups.

CRF原发病为慢性肾炎27例、急进性肾炎3例、原发性高血压9例、糖尿病9例、多囊肾6例、狼疮肾6例，把这60例CRF患者根据中华内科杂志编委会肾脏病专业组于1992年6月在安徽太平举办的原发性肾小球疾病分型、治疗及疗效判定专题座谈会的标准分为四期第1期：肾功能不全代偿期、第2期：肾功能不全失代偿期、第3期：肾功能衰竭期、第4期：尿毒症期；本研究分为轻、中、重症（肾功能衰竭期及尿毒症期）3组来对照观察。

OBJECTIVES: To predict duration of azotemia and distinguish acute renal failure clinically from chronic renal failure by measuring the concentration of hair creatinine and analysing the correlation between Hcr and serum creatinine in 59 patients with acute renal failure and 64 patients with chronic renal failure .

目的：通过对59例急性肾功能衰竭(Acute renal failure，ARF)病人和64例慢性肾功能衰竭(Chronic renal failure，CRF)病人头发肌酐含量(Hair creatinine concentration，Hcr)测定、比较ARF组和CRF组病人就诊时30-40mm段头发肌酐含量之间的差别、对Hcr与血肌酐浓度(Serum creatinine，Scr)相关关系的研究，在临床上利用头发肌酐含量测定来判定肾功能衰竭持续的时间，进一步鉴别急、慢性肾功能衰竭。

Results摘要: The incidence rates of renal dysfunction, shock, cardiovascular failure and gastrointestinal hemorrhage, the score of acute physiology and chronic health evaluation Ⅱ and the frequencies of pulse and breath in the severe hypoalbuminemia group were all higher than those in the mild hypoalbuminemia group (P＜0.05 or P＜0.01). The differences of incidence rate of hepatic failure and the scores of Ranson and Balthazar CT between these two groups had no statistical significance (P＞0.05). The incidence rate of infection and the mortality in the severe hypoalbuminemia group were higher than those in the mild hypoalbuminemia group (P＜0.01) in the later stage of SAP.

结果摘要：重度低白蛋白血症组肾功能衰竭、休克、心衰及消化道出血的发生率高于轻度低白蛋白血症组（P＜0.01，肝功能衰竭发生率两组比较无统计学差异；Ranson评分及Balthazar CT评分两组间比较，差异无统计学意义（P＞0.05）；重度低白蛋白血症组的急性生理和慢性健康评价指标Ⅱ（acute physiology and chronic health evaluationⅡ， APACHEⅡ）评分、脉搏和呼吸频率均明显高于轻度低白蛋白血症组（P＜0.05或P＜0.01；重度低白蛋白血症组后期感染发生率及病死率均高于轻度低白蛋白血症组

The differences of incidence rate of hepatic failure and the scores of Ranson and Balthazar CT between these two groups had no statistical significance (P＞0.05). The incidence rate of infection and the mortality in the severe hypoalbuminemia group were higher than those in the mild hypoalbuminemia group (P＜0.01) in the later stage of SAP. Conclusion: Hypoalbuminemia in the early stage can accelerate the deterioration in pathophysiology of SAP.

结果：重度低白蛋白血症组肾功能衰竭、休克、心衰及消化道出血的发生率高于轻度低白蛋白血症组（P＜0.01，肝功能衰竭发生率两组比较无统计学差异；Ranson评分及Balthazar CT评分两组间比较，差异无统计学意义（P＞0.05）；重度低白蛋白血症组的急性生理和慢性健康评价指标Ⅱ（acute physiology and chronic health evaluationⅡ， APACHEⅡ）评分、脉搏和呼吸频率均明显高于轻度低白蛋白血症组（P＜0.05或P＜0.01；重度低白蛋白血症组后期感染发生率及病死率均高于轻度低白蛋白血症组

Results: The incidence rates of renal dysfunction, shock, cardiovascular failure and gastrointestinal hemorrhage, the score of acute physiology and chronic health evaluation Ⅱ and the frequencies of pulse and breath in the severe hypoalbuminemia group were all higher than those in the mild hypoalbuminemia group (P＜0.05 or P＜0.01). The differences of incidence rate of hepatic failure and the scores of Ranson and Balthazar CT between these two groups had no statistical significance (P＞0.05). The incidence rate of infection and the mortality in the severe hypoalbuminemia group were higher than those in the mild hypoalbuminemia group (P＜0.01) in the later stage of SAP.

结果：重度低白蛋白血症组肾功能衰竭、休克、心衰及消化道出血的发生率高于轻度低白蛋白血症组（P＜0.01，肝功能衰竭发生率两组比较无统计学差异；Ranson评分及Balthazar CT评分两组间比较，差异无统计学意义（P＞0.05）；重度低白蛋白血症组的急性生理和慢性健康评价指标Ⅱ（acute physiology and chronic health evaluationⅡ， APACHEⅡ）评分、脉搏和呼吸频率均明显高于轻度低白蛋白血症组（P＜0.05或P＜0.01；重度低白蛋白血症组后期感染发生率及病死率均高于轻度低白蛋白血症组

Results Forty three cases were died from cerebral hernia before operation 1 week, in which 30 cases with bilateralis mydriasis, and the other 13 cases with half mydriasis. Twenty seven cases died from various complication during 2～3 weeks, in which 11 cases with pulmonary infection, 6 cases with upper gastrointestinal hemorrhage, 5 cases with acute renal failure, 3 cases with multiple organ failure, 1 case with heart failure, 1 case with metabolic disorder of body fluid.

结果术 脑疝形成使中枢衰竭在1周内死亡者43例，其中双侧瞳孔散 30例，单侧瞳孔散大13例；各并发症在2~3周内死亡者27例：肺部感染11例，上消化道出血6例，急性肾功能衰竭5例，脏器功能衰竭3例，心功能衰竭1例，体液代谢紊乱1例。

It is usually a manifestation of widespread cascular disease and although it may be symptomless, many patients with ARVD present with the effects of extra-renal vascular disease, such as peripheral vascular, coronary heart and cerebrovascular disease.

ARVD是高血压和慢性肾功能衰竭常见原因，也是老年终末期肾功能衰竭患者接受透析程序治疗的最常见肾病诊断之一。在这些患者中，肾损害的原因仍然是有争议的问题。ARVD患者死亡率高，尤其是那些有肾功能衰竭者。

Results 6 cases died perioperatively with a mortality of 6.21%,inc luding 3 with multiple system organ failure,2 wiuh low cardiac output syndrome,1 with renal failure.Among the alive cases,6 suffered from low cardiac output syn drome,6 with multiple system organ failure and 1 with renal failure,but all of t hem were successfully rescued by positive therapy,18 suffered from pulmonary inf ection and 3 with incision infection postoperatively,6 with tracheotomy,1 with l ower limbs necrosis and amputation.

结果 围术期死亡6例，病死率6.21%，其中多系统器官衰竭3例，低心输出量综合征2例，肾功能衰竭1例；存活患者中出现低心输出量综合征6例，并发多系统器官衰竭6例和肾功能衰竭1例，经积极治疗后治愈；术后出现肺部感染18例；手术切口感染3例；气管切开6例；肢体坏死而截肢1 例。

Methods We developed hepatic failure by two methods.(1) Surgical moldel of hepatic failure: Under general anesthesia, an end-to-side portocaval shunt was performed in seven trial minipigs. Forty-eight hours later after operation, these minipigs underwent transient total liver ischemia for 4 hours by ligating the hepatoduodenal ligament.

应用中国实验小型猪7头，采用Ⅰ期门静脉－下腔静脉吻合、Ⅱ期（48h后）供肝动脉暂时结扎4h的方法建立缺血性急性肝功能衰竭动物模型；中国实验小型猪6头给于1.2g/kg的D-氨基半乳糖诱导肝功能衰竭，建立药物性急性肝功能衰竭动物模型。

Under the same concentration, tadalafil induce higher ratio of relation responses in the smooth muscles of CRF rabbit cavernosal strips, compared with papaverine and sodium nitroprussiate, with most significant difference occurring under the concentration indicators of 10-5 mol/L and 10-4 mol/L (P.01). Conclusions The effects of tadalafil on relaxation responses in CRF rabbit cavernosal strips highly depend on its concentration. The effect of tadalafil on relaxation responses in CRF rabbit cavernosal strips is better than that of papaverine and sodium nitroprussiate. Tadalafil may be an effective drug for treating CRF reduced erection dysfunction.

同一浓度下，他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张百分比与罂粟碱、硝普钠相比较，舒张百分比均大于罂粟碱和硝普钠，且在10~(-5)mol/L、10~(-4)mol/L浓度，他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张百分比，与罂粟碱、硝普钠相比较有显著性差异(P＜0.01)结论他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张反应的影响具有浓度依赖性，他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张反应的影响优于罂粟碱及硝普钠，他达拉非可能是治疗慢性肾功能衰竭性阴茎勃起功能障碍的理想药物。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。