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We discovered that the mechanisms of borneol opening BBB involved (1) promoting the tight junction of endothelial cells opening:(2) increasing the quantity of pinocytosis vesicle in endothelial cells and enhance the pinocytosis;(3) inhibiting the activation of P-glycoprotein (P-glycoprotein is an efflux pump of drugs) and increase the permeability of BBB;(4) reducing the expression of intercellular adhesion molecule-1 in brain microvessel endothelial cells;(5) increasing the concentration of Ca〓 in brain microvessel endothelial cells;(6) increasing the activation of eNOS in brain microvessel endothelial cells.

随后,在对冰片开放血脑屏障的机制作进一步的研究时又发现,冰片开放血脑屏障的机制包括以下几个方面:(1)冰片可使血脑屏障内皮细胞间的紧密连接开放;(2)冰片能使内皮细胞内的囊泡数量增加,吞饮功能增强;(3)冰片能抑制P-糖蛋白的活性(P-糖蛋白是一种药物外排泵),而使血脑屏障的通透性增加;(4)冰片能使脑微血管内皮细胞ICAM-1表达量减少;(5)冰片使脑微血管内皮细胞内的Ca〓浓度升高;(6)冰片可升高脑微血管内皮细胞eNOS的活性。

Discard the common things, focus on the narrate of particular and aberrance things; Use the description of present and future tense to give us a feeling of reality which shows the irresistible of foreordination. Fully shows the theme of "Tragedy Foreordination "; Through the change of visual angle make the narrate naturally revealed; Use the nicety and pithiness image description impel reader's expand of emotion; Through the exactitude language to break the normal sense of emotion.

余华用重复与循环的结构去成就特殊的人物命运,抛弃现实常规事件,钟情于对非常规及变异事件的叙述;以一种现在式或过去将来式的时间描述带来身临其境的感觉,展示了宿命的不可抗拒绝性,充分体现了"悲剧宿命"的主题;通过变化的视角让叙述以最自然的形态展示出来;使用准确有力的意象描写,推动读者情感发展;通过精准的语言表达,突破常规情感体验。

objective to explore the relationship between expression of galectin-3 with the invasiveness of pituitary adenomas.

目的 探讨galectin-3表达与垂体腺瘤侵袭性的关系。

At the same time, it also help us understand the pleiotropic action of simvastatin.

这些结果对于从基因表达水平上阐明针刺降脂的机理,以及寻找辛伐他汀治疗作用的多效性机制有着积极意义。

It's the "A-bike", the brainchild of British inventor Sir Clive Sinclair, who made history in the 1970s by developing the world's first pocket calculator.

本学期"口语之窗"共介绍了12大项功能交际项目,我们把各项常见表达法放在真实的语境中进行了辅导,增强了语言的运用性。

Mehtod The patients with pollinosis,asthma or atopic dermatitis were selected and treated with Minkang for 6 months and the relief of clinical symptoms were observed.IgE and relative genes were in laboratory.

方法选择花粉症、哮喘、特应性皮炎患者进行治疗,共治疗6个月,观察临床症状改善情况,实验室检测IgE和过敏相关基因表达的改变情况。

Diabetic retinopathy is one of the most serious microvessel complications of diabetes,it is a main cosmopolitan blindness disease. In recent years, with the molecular biology development, the recognition of the mechanism of DR is more profound and consummate. Most researchers consider that hyperglycaemia, polyalcohol inositol metabolism abnormality, changes of hemorrheology, oxidative stress, inflammation/immune system activation, cytokines/growth factors expression or activity change and so on result in DRs onest and development.

糖尿病性视网膜病变(diabetic retinopathy, DR)是糖尿病最严重的微血管并发症之一,也是一种世界性的主要致盲眼病,近年来随着分子生物学方面的研究进展,对DR发病机制的认识进一步深入和完善,认为高血糖、多元醇肌醇代谢异常、血液流变学改变、氧化应激、炎症/免疫系统活化、细胞因子/生长因子表达或活性改变等导致DR的发生发展。

Expression of the caspase 9 gene and its polymorphism distribution in gastric cancer.

胃癌组织中caspase 9的表达及其多态性变化。

Objective: To analyze the expression of cyclooxygenase-2(COX-2) in patients with familial adenomatous polyposis and to discuss the possible role of COX-2 in adenoma formation and cancerization.

目的:分析环氧化酶2(COX-2)在家族性腺瘤性息肉病中的表达,探讨COX-2在腺瘤形成以及癌变过程中的可能作用。

Objective To obtain the functional fusion protein of rhoptry protein 2(ROP2) and major surface antigen 1 of Toxoplasma gondii in order to further prepare for the diagnosis and polyvalent vaccines of toxoplasmosis.

目的构建编码弓形虫RH株棒状体蛋白2(ROP2)和主要表面抗原1的重组表达质粒,纯化和复性的融合蛋白为弓形虫病快速诊断试剂盒及蛋白质疫苗的研制作准备。

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推荐网络例句

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。