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According to experimental results and etiopathogenisis and pathology of osteoporosis , and analyzing review investigation on hepcidin、associations of bone metabolism and iron metabolism and relations of ferri ion and calcium ion,we can make conclusions as follows: 1、We applied single manmade intervention approach to induce osteoporosis model in this study, there was no other influential factor. In the termination of test , rats bone density and bone histological anatomy indicated that osteoporosis model was creditable,meanwhile hepatic functional enzyme and hepatic microtome section demonstrated that hepatic function had noci-influence induced by medicinal herbs resource. Accordingly, we could believe that hepatic hepcidin gene expression and serum hepcidin contents can represent internal iron metabolism changes at selected test time. 2、In this investigation, different findings between test group and control group indicated that:according to changes of hepcidin gene expression measured by RT-PCR and changes of serum hepcidin contents determined by ELISA kit , there were correlations between hepcidin and rat osteoporosis model induced by retinoic acid. 3、Under the condition of this investigation,there was a interactive hypothesis as follows: Hepcidin iron metabolism←→ferriion←→calcium ion←→osteoporosis.

根据本次实验结果,对骨质疏松的病因病理的认识及铁代谢与铁调素、骨代谢与铁代谢关系、铁离子与钙离子的关系系列研究的回顾,经分析得出如下结论:1、本研究骨质疏松模型采用单一人工干预方法,没有其他影响因素;实验结束时大鼠骨密度、骨组织学检查表明骨质疏松形成,同时肝脏功能酶和HE切片显示肝脏功能未受药源性产生明显损伤性影响;因此,同期不同时间组大鼠肝脏铁调素基因表达、血清铁调素含量可以代表体内铁代谢不同时间的变化。2、在本研究中,模型组与对照组研究结果的差异表明:铁调素基因RT-PCR变化、血清铁调素ELISA测定含量变化与维甲酸制作的大鼠骨质疏松模型形成有实验相关性。3、在本研究平台下,形成了一个互相影响的假设图:铁调素←→铁代谢←→铁离子←→钙离子骨质疏松。

GABA interneurons relatively resist ischemia-reperfusion injury,and the increasing expression of GAD65 in 3 d after ischemia-reperfusion can be a compensatory mechanism to reduce the hyperexcitability associated with ischemia-reperfusion.

GABA能中间神经元对缺血相对耐受;全脑缺血-再灌注3天,GAD65的表达增多可能是代偿性的机制,以减轻脑缺血后的高兴奋性。

Results The expression of MMP-2 and MMP-9 was detected in normal anterior hypophysis, non-invasive and invasive macropituitary adenomas.

采用免疫组化SP法检测正常垂体前叶组织、侵袭性和非侵袭性垂体腺瘤组织中基质金属蛋白酶-2和9及其组织抑制因子的表达,结果进行统计学分析。

By immunochemistry staining, both epithelium marker and mesenchyme marker were positive, which made further support for diagnosis.

3免疫组织化学标记,出现上皮性抗体和间叶性抗体的同时表达,进一步支持诊断。

Through the study, the author finds that the advertisers use different kinds of mood adjuncts, modal auxiliaries to claim different degrees of certainty and uncertainty so as to make the advertisements convincing as well as revealing; the advertisers use the present tense to turn to the readers intermittently and to make implicit evaluations of their products/services along the way; use multiple means to realize the imperativeness in advertisements and they address the readers as "you" in advertising textual world to create the pull for the readers to get into the real situation.

具体表现为:广告商通过语气状语、情态助动词、各种认识论性的情态表达造成不同程度的确定与不确定,从而使其广告即有揭示性又保持可信度;使用现在时不时地在广告中直接对读者说话,同时作隐性的评价;使用祈使结构等来实现祈使和礼貌意义;广告主在广告中称呼读者为"你"对读者造成向里的拉力,使读者得以进入广告中的情境。

Generally speaking, traditional Chinese poems are characterized by their suggestiveness, subtlety, implicitness and simplicity, which manifest a kind of fuzzy beauty.

模糊性是诗歌语言,尤其是中国古典诗歌语言的一种属性,其中的模糊表达方式集中体现了模糊美,同时对中国古典诗歌的赏析也体现了审美活动的模糊性。

Results These two patients were confirmed to suffer from DMD. They were characterized by typical features of DMD including typical clinical manifestations, increased serum enzymes, EMG presenting myogenic impairment, HE staining presentation belonging to DMD, negative dystrophin in brother, and inconstantly positive on the sarcolemma of sister. Furthermore, no deletion or duplication was found in the 1-79 exons of dystrophin gene. The suffering brother and sister carried the same maternal X chromosome.

结果 兄妹二人符合DMD诊断,具有典型的DMD临床表现,肌酸激酶、肌酸激酶同工酶、乳酸脱氢酶、羟丁酸脱氢酶和谷草转氨酶的水平均显著高于正常值,肌电图呈肌源性损害,肌肉HE染色符合DMD,男患者的抗肌萎缩蛋白表达阴性,女患者的少量肌纤维仍可见不连续膜阳性,两患者抗肌萎缩蛋白基因的1~79号外显子未见缺失和重复突变,女患者与男患者携带相同的母源性X染色体。

The research is to approach the relation between every indicatrix with atrial fibrillation's happening and development through investigating the change of the gene expression of cluster of differentiation 11b (CD11b) on polymorphoneucler, interleukin-6(IL-6) and tumor necrosis factor-αin right atrial appendage altered in patients with chronic atrial fibrillation.

本研究通过观察CD11b、IL-6和TNF-α在窦性心律及伴有慢性心房颤动的风湿性瓣膜病患者心肌中基因表达的改变,来探讨各指标与AF发生发展的关系。

Objective To study the mechanism of haze formation and to investigate the expression of platelet-derived growth factor mRNA in corneal epithelium and stroma after photorefractive keratectomy.

目的 研究角膜上皮下混浊形成的发生机制,检测准分子激光屈光性角膜切削术后角膜上皮和基质血小板源性生长因子表达的变化。

Objective To study the expression of p63 protein in seborrheic keratosis and to investigate the correlation between p63 and SK.

目的 研究p63蛋白在脂溢性角化病中的表达,探讨其与脂溢性角化病发病的关系。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。