表示原因的

In clinical. acetylcholinesterase inhibitors reduce the breakdown of synaptic acetylcholine, have been modestly effective in improving the cognitive deficits of Alzheimer's disease.The goal of this work is to determine enzyme kinetics and mechanisms of acetylcholinesterase and butyrlcholinesterase inhibition by five cardiovascular drugs, lovastatin, simvastatin, amlodipine besylate, nifedipine, and hydralazine hydrochloride, and two benzodiazepines, diazepam and chlordiazepoxide hydrochloride. All drugs in this study are reversible mixed-type inhibitors of acetylcholinesterase and butyrylcholinesterase. The pKi values for acetylcholinesterase and butyrylcholinesterase inhibition by the cardiovascular drugs are linearly correlated with the molecular weights of the drugs with the slopes of 0.005 and 0.0021, respectively. Therefore, van der Waals' interactions between acetylcholinesterase and the cardiovascular drugs are stronger than those between butyrylcholinesterase and the drugs. This is probably due to a smaller active site gorge and a more significant peripheral anionic substrate binding site of acetylcholinesterase than those of butyrylcholinesterase.

本研究之目的系决定乙醯胆碱酯酵素和丁醯胆碱酯酵素被五种心脏血管药物lovastatin， simvastatin， amlodipine besylate， nifedipine、hydralazine hydrochloride和两种benzodiazepines：diazepam和Chlordiazepoxide hydrochloride的抑制作用之动力学及机转，这些药物都是乙醯胆碱酯酵素和丁醯胆碱酯酵素的可逆性、混合型之抑制剂，实验结果显示，五种心血管药物对於乙醯胆碱酯酵素及丁醯胆碱酯酵素抑制之pKi值和药物之分子量呈直线之关系，斜率分别为0.005及0.0021因此丁醯胆碱酯酵素，与心血管药物间之凡德瓦作用（van der Waals' ）比乙醯胆碱酯酵素与心血管药物间者弱，这可能原因是丁醯胆碱酯酵素之活性区域比乙醯胆碱酯酵素之活性区域更宽广，但丁醯胆碱酯酵素之周边阴离子区域不及乙醯胆碱酯酵素之周边阴离子区域者明显重要，由於五种心血管药物对於乙醯胆碱酯酵素和丁醯胆碱酯酵素抑制之pKi值存在著线性关系表示此种抑制作用系经过共同之反应机理。

But none have been found. That means any oceans were cold or short-lived or ice-covered or otherwise hostile to carbonates.

这表示火星上的任何海洋都是寒冷的、或存在时间很短、或被冰覆盖、或有其他原因，而不利於碳酸盐形成。

There's no definitive reason why such deformities happen, said Cliff Thompson, a retired professor of genetics at the University of Pittsburgh at Johnstown.

约翰斯顿市匹兹堡大学现已退休的遗传学教授克里夫·汤姆森表示，导致这种畸形鸡出现的原因还不得而知。

He told reporters that his current treatment is very good, but needto go back to work for a period of time, and said with a smile, because the reasons for chemotherapy, he Diaoguang hair, longhair and so on have to do better,"Long hair It also takes a long time do."

他告诉记者，目前自己的治疗情况非常好，但回去工作还需要一段时间，并笑着表示，因为化疗的原因，他现在头发都掉光了，要等头发长好了才行，"头发长出来也需要很长时间嘛"。

"One of the reasons Wenzhou is now in trouble is that the companies do not have enough capital to modernise," he says.

他表示：温州目前陷入困境的原因之一，在于这些企业没有足够的资金进行现代化改造。

Less tangibly , heads say children have come to British private schools to enjoy an unalloyed "British" education.

校长们表示，另一个相对不那么易懂的原因就是，孩子进入英国私人学校是为了享受一个纯粹的"英国"教育。

And if the Tridentine prohibition be still urged, it may be truly said that the pope has the right to abrogate the decrees of councils, and is the best judge of the reasons that legitimize such abrogation.

如果德律但丁禁令仍然呼吁，它可能真正表示，教宗也有权废除法令，议会，是最好的评判的原因合法化，如废止。

Ten percent of those questioned said they needed to be contactable at all times because of work.

有百分之十的受访者表示因为工作原因需要随时保持手机畅通。

Ten percent of those questioned said they needed to be contactable at all times because of work.

有百分之十的受访者表示由于工作原因需要随时保持手机畅通。

The US current account deficit is forecast to increase again in 2006, Mr Rato said, partly because of the impact of high energy prices.

拉托同时表示，预计美国经常账户赤字将在2006年再次扩大，部分原因是能源价格高企的影响。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了