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There were 36 males and 40 females,with the average age of 47.7 years.36 patients presented with sciatica and perineal numbness,11 patients had painless mass and the other 20 were identified due to other causes.Among 67 benign neurogenic tumors,54 were originated from S1-S3 nerves,3 from S4-S5 nerves and 11 from the presacral space without caudal involvement.Giant cell tumor was found in 60 patients,which included 24 males and 36 females,with an average age of 32 years.Upper sacrum(S1-S2) was involved firstly.There were 56 patients(average,37.7 years) diagnosed as other primary benign bone tumors,which included 24 cases of teratomas,epidermoid cyst or dermoid cyst.Other malignant tumors,including chondrosarcoma (17),Ewing′s sarcoma/PNET(14),multiple myeloma(12),lymphoma(6) and osteosarcoma(6) were found in 64 patients.

其中脊索瘤95例,男62例,女33例,平均年龄55.7岁,骶尾区疼痛是主要症状(82例),半数以上患者伴有坐骨神经痛,肿瘤多先累及低位骶骨(S3~S5);神经源性肿瘤76例,男36例,女40例,平均年龄47.7岁,神经纤维瘤43例,神经鞘瘤24例,恶性神经鞘瘤9例,主诉多为坐骨神经痛、会阴部麻木(36例)和无痛性包块(11例),20例患者为查体或其他原因检查时发现,67例骶骨良性神经源性肿瘤起源于S3以上神经者54例,起源于S3以下神经者3例,发生于骶前未累及骶管者10例;骨巨细胞瘤60例,男24例,女36例,平均年龄32岁,腰骶尾部不适(37例)、坐骨神经痛(21例)是主要的临床表现,肿瘤多先累及上位骶骨(S1~S2);骶骨其他原发良性肿瘤及瘤样病变56例,包括畸胎瘤、皮样囊肿、表皮样囊肿共24例;其他原发恶性肿瘤64例,包括软骨肉瘤17例,尤文肉瘤14例,多发性骨髓瘤12例,成骨肉瘤6例等。

The five most common benign lesions were dermoid cyst and epidermoid cyst, cavernous hemangioma, lymphangioma, pleomorphic adenoma, orbital inflammation. The five most common malignant lesions were lymphoma, lacrimal adenoid cystic carcinoma, rhabdomyosarcoma, melanoma, sebaceous gland carcinoma.

位于良性病变前5位的分别是皮样囊肿及表皮样囊肿、海绵状血管瘤、淋巴管瘤、泪腺混合瘤、慢性炎症和炎性假瘤;位于恶性肿瘤前5位的分别是淋巴瘤、泪腺囊腺癌、横纹肌肉瘤、黑色素瘤、皮脂腺腺癌。

Results With the expression in normal salivary gland as a standard, low C-erbB-2 mRNA expression was seen in adenolymphoma, basal cell adenoma. However, various degrees of over-expression of C-erbB-2 oncogene mRNA were detected in pleomorphic adenoma, mucoepidermoid carcinoma,acinic cell carcinoma ,adenoid cystic carcinoma ,papillary cystic carcinoma,and myoethelial cell carcinoma.

结果 正常涎腺和涎腺肿瘤中发现不同程度C-erbB-2mRNA的表达,以正常涎腺组织的表达水平为基准,在腺淋巴瘤、基底细胞腺瘤呈现低表达、无表达或与正常涎腺组织表达水平相似,多形性腺瘤、粘液表皮样癌、腺泡细胞癌、腺样囊性癌、乳头状囊腺癌和肌上皮癌则呈现不同程度的过表达。

Methods Twenty-two patients (12 male,10 female)histologically proved for epidermoid tumor of the cerebellopontine angle area were studied by using MR equipment.

目的 探讨磁共振弥散加权成像、液体抑制反转恢复序列在桥小脑角区表皮样囊肿诊断中的应用价值方法收集我院经手术病理证实的表皮样囊肿22例,男12例,女10例,行MR检查。

In ACC, NGF,TrkA and p75 mainly existed in cells of duct-like, cribriform and mass-like structures.According to the optical density scanning of immunohistochemistric stain of NGF and TrkA in salivary gland and tumor tissues and quantification analysis, it was shown that the average optical density of NGF and TrkA increased in order of salivary gland tissues around neoplasm, mucoepidermiod carcinoma, and adenoid cystic carcinoma.

2叫 吉林大学硕士学位论文通过对NGF和TrkA在涎腺组织和涎腺肿瘤中的免疫组织化学染色结果进行光密度扫描,对所测平均光密度定量分析,结果显示:NGF和TrkA平均光密度值按照肿瘤周围涎腺组织、豁液表皮样癌和腺样囊性癌依次升高,统计学分析在各组间均有极显著差异(P.01),表明NGF和TrkA通过自分泌机制调控涎腺腺样囊性癌和豁液表皮样癌的生长与增殖,通过旁分泌机制参与涎腺腺样囊性癌向神经周围的浸润。

Most lesions of SD including bony deformities could be diagnosed with MRI. But the differential diagnosis of epidermoid between dermoid was still difficult.

MRI能正确、全面地诊断包括椎体畸形在内的大多数脊柱神经管闭合不全病变,但表皮样囊肿和皮样囊肿的鉴别仍存在困难。

Objective To investigate the development and prognosis of epidermoid cyst from buried de-epithelialized flap part.

目的 了解埋置于组织中去表皮皮瓣部分表皮样囊肿的发生和转归。

MRI especially DWI play an important role in the detection and differential diagnosis of intracranial epidermoid cyst.

无论在颅内表皮样囊肿病灶检出还是在信号特异性方面,DWI均优于MRI平扫以及T2-FLAIR,是颅内表皮样囊肿最具诊断价值的扫描技术。

OBJECTIVE: To discuss the expressions of 2 sub-types of SSTR, SSTR1 and SSTR2 in human salivary gland mucoepidermoid carcinoma(MEC-1 ) and the high metastatic cell strain(Mc3) of human mucoepidermoid carcinoma and the differences of these two receptors in the binding with SSTR radioactive genin, 125I-RC-160, and the correlations with prngnostic rehabilitation.

目的:探讨人涎腺粘液表皮样癌细胞系(MEG-1)及人粘液表皮样癌高转移细胞株(Mc3)生长抑素受体两种亚型(SSTR1、SSTR2)的表达与SSTR的放射配基125I-RC-160的结合差异与预后康复的相关性。

Methods The expression of EMMPRIN and MVD were examined in 28 cases of pleomorphic adenoma, 25 cases of mucoepidermoid carcinoma, 33 cases of adenoid cystic carcinoma as well as 9 cases of normal salivary glands as comparison control by immunochemistry SP method.

用SP免疫组织化学法检测9例正常涎腺组织,28例多形性腺瘤,25例黏液表皮样癌,33例腺样囊性癌中EMMPRIN的表达和MVD值。

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