表皮松解

I have finally learned how to say, that I have a rare orphan genetic skin disorder named recessive dystrophic epidermolysis bullosa.

现在我终于学会解释自己的病了：这是一种罕见的遗传性皮肤病，叫隐性遗传营养不良型大疱性表皮松解症。

Methods 10 cases of anti-P_(200) pemphigoid sera were collected. The skin sections from 6 cases of recessive dystrophic epidermolysis bullosa were studied with these sera by indirect immunofluorescence.

方法收集了10例抗P_(200)类天疱疮血清，对6例隐性遗传性营养不良性大疱性表皮松解症皮肤切片进行了间接免疫荧光研究。

Dystrophic epidermolysis bullosa is a group of genetic disease caused by loss-of-function mutations in the type Ⅶ collagen gene. The clinical phenotype is characterized by the blistering and scaring of the skin from trauma and there is increased complication of squamous cell carcinoma, which is the major cause of death in patients with DEB.

营养不良性大疱性表皮松解症是一种由于人体Ⅶ型胶原基因突变或缺失所引起的遗传性疾病，临床特征为创伤诱发的水疱和瘢痕，并发症以恶性鳞状细胞癌多见，是导致患者死亡的主要因素，目前仍无有效的治疗方法。

Here, we report on the first systematic long-term study of fibroblast therapy in a mouse model for recessive dystrophic epidermolysis bullosa, a severe skin-blistering disorder caused by loss-of-function of collagen VII.

我们报道了第一例长期性系统性的关于成纤维细胞治疗隐性营养不良性大疱性表皮松解症小鼠模型的研究。隐性营养不良性大疱性表皮松解症是一种严重的由于VII-胶原蛋白功能丧失引起的出疱性皮肤病。

Results All the 10 anti-P_(200) pemphigoid sera could react with basement membrane zoneof 5 cases of recessive dystrophic epidermolysis bullosa, while epidermolysis bullosa acquisita sera were negative in these skins.

结果发现10例抗P_(200)类天疱疮血清均与5例RDEB皮肤基底膜带反应，而获得性大疱表皮松解症血清对这些皮肤为阴性。

Epidermolysis bullosa is the name given to a group of genetic disorders that lead to fragile skin.

大疱性表皮松解症的名称是给一组遗传性疾病导致脆弱的皮肤。

Preclinical progress has been achieved in the treatment of wounds, epidermolysis bullosa and ichthyosis.

前期的临床实验在治疗创伤，大疱性表皮松解症和鱼鳞病上已经取得了进展。

Objective To study the gene mutation in a pedigree with Dowling-Meara type epidermolysis bullosa simplex .

目的研究Dowling-Meara亚型单纯型大疱性表皮松解症一家系的基因突变。

The ultrastructural localization of the immunoglobulin and complements in diseased skin of several sub-epidermal bullous diseases, including 1 case of Bullous Pemphigoid , 3 cases of Epidermolysis Bullous Acquisita , 1 case of Bullous System Lupus Erythematosus and 2 cases of Linear IgA Bullous Dermatoses , was detected by postembedding immunogold electronmicroscopic technique.

利用直接免疫金标电镜技术同时检测几种表皮下大疱病：大疱性类天疱疮1例、获得性大疱性表皮松解症3例、大疱性SLE1例、线性IgA大疱性皮肤病2例皮损组织中免疫球蛋白和补体〓，比较它们沉积部位和形态的异同，以探讨该技术在鉴别不同表皮下大疱病中的意义。

Compared studies of routine DIF and DIF of 1mol/L Nacl-separated patients skin and IIF using 1mol/L NaCl-separated normal human skin as substrate were clone in 19 patients with bullous pemphigoid and 5 with epidermolysis bullosa acquisita.

对19例大疱性类天疱疮和5例获得性大疱性表皮松解症病人进行了常规DIF、1mol／LNaCl分离表皮DIF和1mol／LNaCl分离正常人皮肤IIF的对比研究。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐