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The results implied that the percentage of diverted traffic volume had a great impact on the total delay of the entire network.

结果表明,转移的交通量大小对于整个路网延误有显著影响。

Measured results show that the chip has a minimum supply voltage requirement of 0.75V.

测试结果表明,该芯片的最低电源电压要求为0.75V。

Studies suggest that taking standardized feverfew leaf extracts that supply a minimum of 250 mcg of parthenolide per day is most effective.

研究表明,服用标准化菲沃菲叶提取物,供应了250微克,每天小白菊内酯最低是最有效的。

There is now a growing mountain of evidence that it is NOT safe to do so.

这一做法是否安全呢?现在有越来越多的证据表明——不安全。

All this suggests that Washington sees Japan, the world's second-largest economy, as a powerful nation.

所有这一切都表明,在美国眼中,作为全球第二大经济体的日本是一个强国。

He drew a rough sketch on his pad showing the position of the entrances to the camp.

他在垫子上画了一幅草图表明营地的入口。

By doing this you will be showing that you have a strong character.

这样做会表明你有坚强的个性。

His face showed that he had a strong character.

他的面相表明他性格坚强。

Results are as followed:1 Exposure of HELF cells to BP caused c-Jun activation,and increased the activity of MAPK,PI-3K,p53 and cyclin D1 pathway.2 BP-induced c-Jun activation was inhibited by dominant negative mutants of extracellular signal-regulated protein kinase or c-Jun NH_2-terminal kinase,but not by p38,impling that JNK and ERK pathways medicate c-Jun activation induced by BP.3 Overexpression of dominant-negative mutants PI-3K and Akt potently blocked phosphorylations of c-Jun and ERK,but not JNK in response to BP,suggesting that PI-3K/Akt pathway positively regulates BP-induced c-Jun activation through ERK.4 Inhibition of p53 by its chemical or molecular inhibitor markedly increased the phosphorylation levels of c-Jun,Akt and ERK upon BP stimulation,indicating that p53 negatively medicates BP-induced c-Jun activation through PI-3K/Akt/ERK pathway.5 The cell lines expressed TAM67 exhibits no significant affecting normal cell growth properties.6 TAM67 was able to significantly block G_1-S transition and subsequent cell proliferation,suggesting that c-Jun is essential for cell cycle alternations elicited by BP.7 Overexpression of TAM67 impaired BP-induced cyclin D1 activation,decreasing expression of E2F1 and pRb,indicating that c-Jun participates in the modulation of BP-induced activation of cyclin D1/pRb/E2F1 pathway.8 Stably expression of TAM67 led to the increases in the expression levels of p53 and p21,elevating phosphorylation level of p53,clearly indicating that c-Jun regulates p53/p21 pathway activation induced by BRCollectively,PI3K/Akt/ERK pathway mediated BP-induced c-Jun activation through p53-dependent mechanism.

结果显示:1BP刺激细胞可促进c-Jun活化,并伴随着MAPK、PI-3K、p53和cyclinD1通路各组成成分的活性增强。2利用MAPK通路的显性失活突变体分别阻断细胞外信号调节激酶和c-Jun氨基末端激酶活性,均可明显抑制BP诱导的c-Jun活化,但阻断p38活性对BP引起的c-Jun活化无明显影响,提示JNK和ERK通路参与调控BP诱导的c-Jun活化。3过表达PI-3K和Akt的显性失活突变体也可显著抑制BP诱导的c-Jun活化,并降低磷酸化ERK的表达水平,但对磷酸化JNK的表达水平无明显影响,说明PI-3K/Akt通路通过ERK正性调控了BP诱导的c-Jun活化。4p53的化学/分子抑制剂能使BP作用的细胞内c-Jun活性明显增加,并同时诱导Akt和ERK的磷酸化水平的升高,表明p53可通过PI-3K/Akt/ERK通路对BP诱导的c-Jun活化进行负性调控。5随后观察转染细胞的生长情况,发现TAM67对细胞正常生长和形态无明显影响。6稳定表达TAM67可有效抑制BP诱导的S期细胞数的增加,提示c-Jun在BP致细胞周期改变的过程中发挥了重要作用。7TAM67过表达能够抑制BP诱导的cyclin D1活化,降低磷酸化Rb以及E2F1蛋白表达水平,表明c-Jun参与调控BP诱导的cyclin D1/Rb/E2F1通路的活化。8过表达TAM67可使BP刺激的细胞中p53、p21总蛋白以及p53磷酸化的表达水平明显升高,可见c-Jun也参与调控BP诱导的p53/p21通路活化。

The geology research of carbonate reservoirs in Ordovician of Tahe oilfield showed that many large dissolved vugs and fractures were developed. The spread of the reservoir take on a very heterogeneous state. And the typical fractured-vuggy reservoirs was formed. According to the combination of the various spaces, the formation was divided into vuggy formation, fractured-vuggy formation and fractured formation. The research showed that development of the vug is relevant to the its position on the structure, the fractures, the water surface and the weathering surface. Multi-phase charge and recharge of the oil in the reservoirs resulted in the complexity of the fluid distribution. So the"Bottle Model"was brought forward to explain the movement of the water-oil contact. The special storage space and the complex fluid distribution lead to the unstability of the production and the complexity of the water cut. In order to explain the characteristic of the fracture-vug unit was brought forward and the basic principle and method of the partition of the fracture-vug unit was formed. The classification and evaluation of the units were performed according the reserve and energy. Based on the research of geology characteristic and the fluid flow in the reservoir the comprehensive numerical simulation plan of the fractured-vuggy reservoirs were established. Through the selection of the simulation unit, fluid flow type and parameter equivalent the triple media reservoir simulation model was established. Considering the practical application the model was resolved by the DKR decomposition conjugate grads method. Based on the fine reservoir description of Dsitrict IV of the Tahe oilfield the various space type were classified and combined together. The geology model of Unit S48 was constructed. Two typical single well model was established according to the geology and the dynamic phenomena. Finally the single well model and the Unit S48 were simulated by the triple media reservoir simulator. Via the local grid refinement and coarsening in the simulation good matchs were gained. Based on the results of the simulation the reserve distribution, percent of reserve produced in various space and the natural energy were analyzed. The fluid was storaged in the fractures and vugs mostly and more than 90% the produced oil came from the systems. The energy belonged to the active one. The results of simulation accorded with the fact and showed the validity and practicability the research and the simulator.

塔河油田奥陶系碳酸盐岩油藏的地质研究表明,其储层中发育着很多大型的溶蚀洞、缝,储层的平面展布呈现出极度的非均质性,形成了典型的缝洞型碳酸盐岩油藏,根据各种孔隙介质在储层中的组合,将储层分为了溶洞型、裂缝-溶洞型和裂缝型三类;研究表明溶洞储层的发育和构造位置、裂缝的发育、潜水面和风化面的位置等因素有关;多期充注的油气成藏模式导致了流体复杂的赋存状态,由此提出了所谓的&瓶子模型&,解释生产过程中油水界面的变化;特殊的储集空间类型和流体分布特征导致油田在开发过程中表现出很大的不确定性和含水变化的复杂性,为了合理的解释油气田开发过程中的动态特征,提出了&缝洞单元&的概念,并制定了&缝洞单元&纵横向划分的基本原则和依据及划分方法,并对&缝洞单元&进行了分类和评价;基于地质特征和流体在其中流动规律的研究,提出了缝洞型碳酸盐岩油藏的数值模拟综合解决方案,通过模拟单元的选择、流动类型和参数的等效,建立了三重介质油藏三维三相数值模拟模型,采用不完全LU分解预处理共轭梯度法进行了求解;在塔河油田4区精细油藏描述的基础上,将各种类型的孔隙空间进行了归类组合,建立了S48单元的地质模型;通过对油井生产动态进行分析研究,建立了两类和油井地质、生产动态相对应的单井模型;最后应用三重介质油藏数值模拟软件对单井模型和S48单元进行了数值模拟,通过局部加密和粗化等技术模拟流体流动规律,取得了很好的拟合效果;结合数值模拟结果,分析了各种介质中的储量分布、储量产出的百分比以及地层的能量,认为塔河油田缝洞型油藏中流体绝大多数储集于缝洞系统之中,所产出流体90%以上也来自于缝洞系统,其底水能量属于较充足的类型;模拟结果和油田实际情况符合较好,说明了地质研究和油藏数值模拟研究的正确性。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。