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Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

成果包括:(1)在生物组织弹性成像方面,研究了多种图像校正方法和应变估计方法,进行了弹性重构和仿体、离体及在体超声弹性成像实验研究;(2)在生物微系统和微血管血流灌注成像方面,制备了三种不同包膜超声造影微泡,研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制,并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究;(3)在阵列式高强聚焦超声治疗与监控成像技术方面,设计制作了新的HIFU换能器,解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题,并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展,具有重要应用前景;(4)在语音听觉系统特别是嗓音康复方面,研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理,建立基于神经、肌肉和空气动力系统的综合补偿调节模型,提出了相应的评价系统。

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

中文摘要:成果包括:(1)在生物组织弹性成像方面,研究了多种图像校正方法和应变估计方法,进行了弹性重构和仿体、离体及在体超声弹性成像实验研究;(2)在生物微系统和微血管血流灌注成像方面,制备了三种不同包膜超声造影微泡,研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制,并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究;(3)在阵列式高强聚焦超声治疗与监控成像技术方面,设计制作了新的HIFU换能器,解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题,并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展,具有重要应用前景;(4)在语音听觉系统特别是嗓音康复方面,研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理,建立基于神经、肌肉和空气动力系统的综合补偿调节模型,提出了相应的评价系统。

The results showed that the light saturation point of potato leaf was about 1400 μmoll(m^2s) and its light compensation point was about 50 μmoll(m^2s), the stomatic conductance and the transpiration rate increased while the intercellular CO2 concentration reduced with the increasing of light intensity between the light compensation point and light saturation point.

试验结果表明:马铃薯叶片光合作用的光饱和点约为1400 μmol/(m^2s),光补偿点约为50μmol/(m^2s)。在光饱和点和光补偿点之间,随著光合强度的增加,叶片的气孔导度和蒸腾速率升高,胞间CO2浓度降低;随著CO2浓度的增加,光合速率升高,其CO2的饱和点约为2000μmol/mol。

Airy Hypothesis: A mode of compensation for isostasy in which topographically elevated areas are compensated by underlying "roots" of crustal material penetrating into the higher density subcrust.

艾里假说:地壳均衡补偿的一种模式,认为地形升高的区域可由它下面扎入更高密度地壳物质形成的&根&来补偿

The susceptance of the capacitor and the ration of the OLTC are regarded as control variables in the reactive power optimization to overcome the disadvantages in application of equal wastage ration method in distribution network.

传统的无功优化技术是以等网损微增率方法为基础的[1],其主要优点是简单、有效,但对于配网来说,却存在两个主要缺陷:由于配网总的无功最优补偿容量无法确定,所以等网损微增率方法无法得到一个较优的补偿方案;在配网的实际运行中,当电压偏差较大时,有载调压变压器往往作为凋节电压的手段而对无功功率的分布产生影响,使得等网损微增率方法难以实现。

This compensation circuit can make the stability of the LDO linear regulator undependent on the effect of load capacitor's equivalent serial resistance, and it also makes the unit gain frequency bandwidth change slightly when the load is varying, thus greatly improving the performance of transient response, Furthermore, on the basis of dynamic frequency compensation, an overcurrent protection circuit is designed.

文章针对LDO稳定性的问题,提出了一种内部动态频率补偿电路,使LDO线性稳压器的稳定性不受负载电容的等效串联电阻的影响,其单位增益带宽也不随负载电流变化而改变,大大提高了瞬态响应特性;采用Hynix 0.5μm CMOS工艺模型对电路进行仿真;此外,该电路在实现动态频率补偿的基础上又加入了系统的过流保护功能,当负载电流大于限制电流时,LDO不能正常工作;当负载电流小于限制电流时,又自动恢复到正常工作状态。

In underbalance circumstances, the response characteristics of partial logging instruments and the influence upon log data are analyzed and the influemce factors of the data on deep-shallow dual laterolog, compensated sonic log and compensated neutron log, etc.

文章对欠平衡状态下部分测井仪器的回应特徵及测井资料受到的影响进行分析,主要考虑了深浅双侧向、补偿声波、补偿中子等资料的影响因素。

On the basis of these studies, we propose a robot track compensation control, and this strategy compensates the robot's track error caused by the structural and unstructural uncertainty well.

并在此神经网络的基础上,提出了基于CVSNN的机器人运动补偿控制策略,良好地补偿了机器人的结构性不确定因素与非结构性不确定因素造成的跟踪误差。

In order to decrease total optical length, a design scheme was employed by selecting mechanically compensated zoom lens with a negative compensator, shortening the focus length of variator and compensator, and increasing the distance between front group and variator. An initial configuration was obtained by solving equations of aberrations. According to aberration theory, the aberrations were corrected by using ZEMAX optical design software.

为缩短筒长,采用负组补偿偏离物像交换变焦结构,缩短变倍补偿系统各组元焦距,增加前固定组和变倍组间距的设计方案,通过解初级像差方程求得初始结构,依据像差理论,利用ZEMAX自动设计软件进行像差校正平衡。

Leakage compens- sation capacity test for the system,under different leaking degree,is given, which proves to be good.

还做了系统在不同泄漏情况下的泄漏补偿能力试验,结果表明系统具有很好的泄漏补偿特性。

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Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在,'歼灭战perfuming自己与胡努特,那麼,他来到和SAT 。

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三叶草是爱尔兰和圣特里克节的标志同时它的寓意是带来幸运。3片心形叶子围绕着一根断茎,深绿色。