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血脑屏障

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That's why BBB experts also will be distributing ...

这就是为什么血脑屏障专家也将分发。。。

METHODS On the basis of the animal model of traumatic DBI caused by free dropping,we measured the water content,the levels of TXB2,6-keto-PGF1α,cAMP and cGMP,and observed the changes of the blood-brain barrier permissibility by the Lanthanum Nitrate labeled electroscope to assess the protective effect of MCPG on the brain tissues after DBI in rats.

在自由落体致DBI模型的基础上,通过测定脑组织含水量、TXB2,6-keto-PGF1α,cAMP,cGMP等水平变化,以及应用硝酸镧标记电镜分析观察血脑屏障的通透性改变,探讨MCPG对DBI的保护作用及其机制。

Under electron microscopic observation, capillaries of SFO are fenestrated ones, the endothelium of them are short of the tight junction, their basement membrane are not intact, the gaps between the endothelium and basement membrane are widened, to which the gaps within the endothelium are opened, the end feet of astrocytes surrond the capillaries not completely, and on the luminal surface of the endothelium some small vesicles are adhere to it, all of which suggesting SFO short of blood brain barrier .

在电镜下观察,穹窿下器的毛细血管为窗性毛细血管,内皮缺乏紧密连接结构,基膜薄而不完整,内皮与基膜之间的间隙宽大,内皮裂隙可通向此间隙,毛细血管内皮腔面可见贴壁小泡,星形胶质细胞脚板未完整包围毛细血管,这些结构特点提示SFO的血脑屏障不完整。

Under electron microscopic observation, capillaries of SFO are fenestrated ones, the endothelium of them are short of the tight junction,their basem ent membrane are not intact, the gaps between the endothelium and basement membrane are widened, to which the gaps within the endothelium are opened, the end feet of astrocytes surrond the capillaries not completely, and on the luminal surface of the endothelium some small vesicles are adhere to it, all of which suggesting SFO short of blood brain barrier.

在电镜下观察,穹窿下器的毛细血管为窗性毛细血管,内皮缺乏紧密连接结构,基膜薄而不完整,内皮与基膜之间的间隙宽大,内皮裂隙可通向此间隙,毛细血管内皮腔面可见贴壁小泡,星形胶质细胞脚板未完整包围毛细血管,这些结构特点提示SFO的血脑屏障不完整。

Rabbits received naloxone HCl intracerebroventricularlyor naloxone methiodide IV, a quaternary compound that does notcross the blood–brain barrier, 5 min before FENT treatment(5 or 50 g/kg, IV).

使用 FENT 治疗(5或50 g/kg ,静脉注射)前5min ,向家兔脑室内注射盐酸纳洛酮或静脉注射甲硫丁氨酸纳洛酮(一种四元化合物,不能透过血脑屏障)。

BACKGROUND: Amphotericin B is firstly used to treat deeply fungous infection; however, the therapeutic effect is poor due to inability to cross the blood-brain barrier.

摘要背景:两性霉素B为治疗深部真菌感染的首选药物,但该药无法通过血脑屏障而对隐球菌性脑膜炎的治疗效果甚微。

Large dose EPO can pass hematic head protective screen and play nerve protects action.

大剂量EPO能通过血脑屏障并发挥神经保护功能。

Dr. Hooper notes that the work is part of the long-range goal of determining the exact role of blood-brain barrier permeability in disease.

Hooper博士指出:这个实验是确定血脑屏障通透性在多发性硬化病中确切作用的大范围实验的一个部分。

Rats of model groups were injected with horseradish peroxidase as an indicator of BBB function and compared with control group.

采用HE染色法、辣根过氧化物酶染色法及免疫组织化学染色法观察正常对照组及模型组各个时间点(3、24、48h、3d、1和2周)海马区锥体细胞的变化、血脑屏障的变化及脑组织MMP-9的表达。

Immunohistochemical localization of inhibin α-subunit in normal mature rats was carried out by using Strept Avidin-Biotin-Peroxidase Complex .The results showed that there was positive immunoreactivity of the McAb to inhibinα-subunit in heart ,kidney , spleen , lymph ,adrenal gland and pancreas cells. It indicated that inhibinα-subunit existed in the above tissues , But no positive sites were seen in hypothalamus, pituitary, lung and liver, that means they have no inhibinα-subunit. Compared with the ovariectomized rats, the hypothalamus and pituitary of the rats injected with inhibin-α fragment(1~32)showed an positive reaction, suggesting that inhibin α-subunit could pass through the blood-brain barrier .

用链霉亲和素-生物素-过氧化物酶(Strept Avidin-Biotin-Peroxidase Complex, SABC)免疫组织化学方法,以抑制素α亚基单克隆抗体对正常雌性性成熟大鼠各组织的抑制素α亚基进行定位观察,结果显示:⑴大鼠心脏、肾、脾、淋巴、肾上腺、胰腺均呈阳性反应,表明存在抑制素α亚基;下丘脑、垂体、肝脏和肺组织呈阴性反应,表明其不存在抑制素α亚基;⑵与去卵巢大鼠相比,外源注射抑制素α(1~32)片段的大鼠其下丘脑和垂体出现阳性反应,说明抑制素α亚基能通过血脑屏障

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Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势,并设计了一款彩色夜视摄像机。

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这一引人注目的地域范围,比喜马拉雅山更加陡峭,是处于西藏东部边缘的朝上翻的边框地带。响应启始于约5500万年前的、缓慢的但却不可阻挡的印度与亚洲地壳板块碰撞,高原已上升至五千米,这种碰撞持续至今,毫无衰退。