血脑屏障

The brain capillary and star glue quality cell which enwrap around it under thenormal condition form the permeation extremely low blood-brain barrier, onlypermit some little molecule to pass; When cerebral isc.

正常状态下的脑毛细血管及包裹在其周围的星形胶质细胞构成了通透性极低的血脑屏障，只允许一些小分子物质通过；当缺血性中风发生时，微血管通透性发生显著改变，这种病理变化与脑内皮细胞损伤导致的功能变化有直接的关联。

Results: Muscone could pass through the normal rat's blood brain barrier into the brain and soon reached the highest peak and remained in higher concentration, and more slowly metabolized as compared with other organs.

用麝香的主要有效成分麝香酮，经大鼠尾静脉注射，按不同时间取其脑等内脏，制备组织样品，用气相色谱法测定其透过血脑屏障的脑内分布和其他脏器分布。

BBB mainly by the pia mater, choroid and brain capillary composition, can prevent invasive micro-organisms, such as brain and spinal cord meninges, to protect the central nervous system from being undermined.

血脑屏障主要是由软脑膜、脉络膜和脑毛细管组成，可以阻止微生物等侵入脑脊髓和脑膜内，从而保护中枢神经系统不受损害。

It has been found that ectogenic GDNF has nervous protective effec,but ectogenic GDNF cannot enter blood brain barrier.

传统观点认为，星形胶质细胞是神经系统的支持细胞，构成神经组织的网架而起支持作用，与神经元的解剖位置关系紧密，参与中枢神经系统的免疫反应，参与构成血脑屏障，目前研究发现，脑缺血时星形胶质细胞异常活跃，通过合成多种蛋白质、细胞因子和神经营养因子等对神经元起保护作用，对缺血性脑损伤的发展和转归具有重要意义。

Multiple factors participated in the process of secondary brain edema and nerve injuries,such as the hydrostatic pressure during formation of the hematoma and clot retraction, activation of blood coagulation cascade, generation of thrombin,erythrocytolysis and the toxicity of hemoglobin, the activation of the complement system, space-occupying effects, rupture of the blood-brain barrier,secondary ischemia around the hematoma, inflammatory reaction of the neurons around hematoma and cell apoptosis.

脑出血后继发水肿及神经损害有多种因素参与，血肿形成过程中的流体静力压和血凝块的回缩、凝血瀑布的激活、凝血酶的产生、红细胞溶解和血红蛋白的毒性、补体的激活、占位效应、血脑屏障的破坏、血肿周围继发缺血、血肿周围组织神经细胞炎症反应及细胞凋亡等。

The technology of culture of exogenetic NGF in vitro is qualified now, however, the exogenetic NGF cant get through blood-brain barrier and blood-nerve barrier because it is a kind of marcomolecular protein, thus its extensive application on clinic is limited, now, many scholors have turned their study direction to enhancing the content of endogenous NGF.

外源性NGF的体外合成技术已基本成熟，然而，外源性神经营养因子作为一种高分子蛋白物质不能通过消化道给药、不能通过血脑屏障和血神经屏障的问题阻碍了它在临床上的广泛应用，所以NGF在临床上并没有真正发挥出其营养神经的作用。

TSRP could decrease brain hydrated amount and markedly lower permeability of blood-brain barrier subjected to 2 h MACO followed by 24 h reperfusion, and this may be a mechanism of TSRP alleviating brain edema during I/R.

茅莓总皂苷各剂量组显著降低缺血2h再灌注6，24，48，72 h脑水肿和其对血脑屏障通透性，这可能是其减轻I/R时脑水肿的机制之一。

The path-physiological mechanism of ICH is complicated, which includes the high intracranial pressure caused by hematom mechanical pressure, the lesion by the decrease of regional cerebral blood flow surrouding the hematom, even regions adjacent to the hematom, Meanwhile, the materials released from hematom including ferrohemoglobin, thrombase, plasma protein and platelet, leucocyte, glusate not only directly injury neurons but also blood brain barrier.

脑出血的病理生理学机制复杂，其中包括血肿的机械压迫所造成的持续的脑缺血性损害；血肿分解后产生的血红蛋白、凝血酶、血浆蛋白、血小板和白细胞、谷氨酸、自由基等毒性物质不仅可直接损伤神经元，而且可损害血脑屏障加重脑水肿。

All C.neoformans contain serine protease; Serine proteinase perturbs the integrity of BMEC of the blood-brain barrier, improves open the level of BBB; Secreted serine protease from pathogenic fungi were virulence.

发现新生隐球菌分泌具有活性的胞外蛋白水解酶并含有丝氨酸蛋白酶成分；新生隐球菌自身分泌的丝氨酸蛋白酶可以干扰构成血脑屏障主要成分内皮细胞的完整性使得血脑屏障开放程度提高；致病性真菌分泌的丝氨酸蛋白酶可能是一种毒性因子。

To date, all stroke clinical trials targeting glutamate receptors have failed, largely because of their side effects, an inefficient delivery of compounds from the blood to the brain or the length of time it takes for the drugs to work effectively.

迄今为止，所有关于中风的谷氨酸受体方面的研究都以失败告终，很大程度是由于副作用的原因，药物不易透过血脑屏障以及过血脑屏障所需时间都会影响药效。

Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势，并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。