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The results show that it is much reasonable to evaluate pharmacodynamics of traditional Chinese drug which treat thoracic obstruction cardialgia in the acute myocardial infarction models with blood stasis in rats.

大鼠"血瘀证"下急性心肌梗死模型与单纯急性心肌梗死模型在心电图变化上存在明显差异,在血流动力学各项指标上无明显差异,提示采用"血瘀证"下急性心肌梗死模型来评价治疗胸痹心痛中药的药效学更为合理。关键词:血瘀;心肌梗死;大鼠 Wistar;血流动力学;心电描记术

Objective To evaluate the effects of tranexamic acid on coagulation and fibrinolysis in patients undergoing thoracotomy.

目的评价氨甲环酸在开胸手术中的止血作用和对开胸手术围术期凝血纤溶功能的影响。

objective to discuss perioperative complication and management of patient with high risk copd following esophagectomy.methods 45 patients with high risk copd underwent esophagectomy with epidural block combined with general anesthesia.perioperative treatment included smoking cessation,chest physiotherapy,prevention and control of infection of air way and appropriate bronchodilators of air way,breathing exercises,nutrition support and oxygen therapy.painkiller was instilled after surgery,early exercises,ensuring unobstruction of the air way,mechanical ventilation was applied when needed.results 3 had hypoxaemia in operation.after surgery,all patients had spo2 somewhat declined.6 had lung infection.6 were removed of bronchial secretion by bronchoscope.2 were supported by ventilator by using intubation.2 underwent tracheotomy.1 had disturbances of acid base balance and treated by using hydrochloric acid muriatic acid.all patients recovered rather smoothly and discharged from hospital.conclusion high risk copd is not the absolute contraindication of esophagectomy.active management before and after surgery ensures the safety and recovery of patients.

目的 探讨重度慢性阻塞性肺疾病简称慢阻肺病人食管切除术围手术期常见并发症及其处理。方法 45例重度慢阻肺的病人在全麻联合硬膜外阻滞下进行开胸食管切除手术,围手术期处理包括术前戒烟、胸部理疗、预防和控制呼吸道感染、解痉化痰、呼吸功能锻炼、营养支持和氧疗;术后硬膜外镇痛、早期锻炼、保持呼吸道通畅,部分病人予以呼吸支持。结果术中3例出现低氧血症。术后所有病人pao2均有不同程度的下降,6例出现肺部感染,6例行纤维支气管镜吸痰,2例通过气管插管给予呼吸机支持,2例行气管切开术,1例酸碱平衡紊乱使用盐酸精氨酸治疗。所有病人均痊愈出院。结论重度慢阻肺病人并非开胸食管切除手术的绝对禁忌证,积极的术前准备和严格的术后管理可减少和控制术后急性发作,有助于确保此类病人的围手术期安全和康复。

Methods Twenty-six NZW rabbits were randomly divided into three groups: a normal control group (fed on normal commercial rabbit diet, n =6), a hyperlipidemic group fed on high-fat ma total cholesterol (TC concentration at the beginning and the 12-week end point of the experiment determined,and all the experimental rabbits were sacrificed, and endothelial function test were performed on thoracic aortic rings prepared from the isolated aorta using the vascular endothelium-dependent relaxation parameter in response to acetylcholine The aortic atherosclerotic lesion expression of LOX-1 mRNA and protein were examined by RTPCR and Western blotting respectively.

方法新西兰大白兔随机分为正常对照组(普通饮食,6只),高脂饮食组(高脂饮食,10只)及普罗布考组(高脂饮食+普罗布考200mg/kg·d,10只)。实验开始前及第12周分别耳缘静脉采血测定血清总胆固醇。第12周处死动物,取胸主动脉,制备离体胸主动脉环对乙酰胆碱的反应以检查内皮功能,RT-PCR与免疫印迹检测凝集素样氧化低密度脂蛋白受体-1(LOX-1)基因与蛋白质表达水平。

At the first day after injection, 3H-TdR was distributed mostly in spleen, thymus , femur , liver and small intestine according to their activity; 3H-TdR was distributed mostly in blood, kidney, liver, lung, sperma, brain, spleen , small intestine , muscle , thymus and femur in turn on the basis of their absorbed dose.

注后1天,按单位组织的放射性活度计,~3H-TdR主要分布于脾脏、胸腺、股骨、肝脏和小肠;按组织器官的吸收剂量计,依次为外周血、肾脏、肝脏、肺、睾丸、脑、心脏、脾脏、小肠、肌肉、胸腺和股骨。

Objective To investigate the relationship between the blood supply of sternocleidomastoid muscle and the formation of sternocleidomastoid psuedotumor in infancy.

目的 观察胸锁乳突肌的血供来源及婴幼儿胸锁乳突肌假性肿瘤的病变特征,探索先天性肌性斜颈的病因与两者之间的关系。

The average number of anterior lymph nodes was 3.83±1.79. Their blood supply originated from the branches of lateral thoracic artery, whose mean diameter and length were 1.04±0.42 and 29.5±12.25 respectively.(3) The average number of posterior lymph node was 2.38±0.97. Their blood supply originated from the lymph node branch of subscapular artery, whose length and mean diameter were respectively 18.78±8.67 and 0.78±0.32.(4) The average number of central lymph nodes was 4.05±1.95. Their blood supply originated from axillary artery whose mean diameter was less than 1mm.(5) The average number of apical lymph nodes was 2.82±1.96. Their blood supply originated from the branches of thoracoacromial artery whose mean diameter was 0.79±0.29mm and length was 10.60±4.13mm.

结果 外侧群淋巴结数量为(3.16±1.72)个,血供属多源性且不恒定;前群淋巴结数量为(3.83±1.79)个,营养血管主要为胸外侧动脉的分支,其外径(1.04±0.42)mm,干长(29.5±12.25)mm;后群淋巴结数量为(2.38±0.97)个,血管来源于肩胛下动脉的淋巴结支,其外径为(0.78±0.32)mm,干长(18.78±8.67)mm;中央群淋巴结数量为(4.05±1.95)个,血管来源于腋动脉的分支,其外径均在1mm以下,干长20mm以上;尖群淋巴结数量为(2.82±1.96)个,营养血管为胸肩峰动脉的分支,外径为(0.79±0.29)mm,干长(10.60±4.13)mm。

Results:(1) cerebrovascular syphilis 1 case,tabes dorsalis 2 cases;(2) Inall cases,Serum and cerebrospinal fluid syphilis antibody reaction showed positive; CSF protein content was increased significantly,and cells increased (3) MRA and DS...

结果(1)脑血管梅毒1例,脊髓痨2例;(2)3例血和脑脊液的梅毒抗体均为阳性;脑脊液蛋白含量增加、细胞数增多;(3)脑血管梅毒患者MRA及DSA显示左大脑中动脉M1段闭塞;左大脑前动脉及左大脑后动脉通过皮层支向左大脑中动脉供血区代偿供血;(4)2例脊髓痨患者头颅及胸髓MRI无特殊发现,肌电图及周围神经活检不支持周围神经受损。

Results:(1) cerebrovascular syphilis 1 case, tabes dorsalis 2 cases;(2) mall cases. Serum and cercbrospinal fluid syphilis antibody reaction showed positive; CSF protein content was increased significantly, and cells in creased (3) MRA and DSA of cerebroascular syphilis show that Mi segment of the left middle cerebral artery is blocked. The left posterior cerebral artery and the left anterior cerebral artery compensate blood supply for the left middle cerebral artery through the conical branch.(4) MRI of head and thoracic cord was normal in 2 cases of tabes dorsalia. Result of EMG and biopsy of suml nerve not manifest damage of peripheral nerveous system.

结果:(1)脑血管梅毒1例,脊髓痨2例;(2)3例血和脑脊液的梅毒抗体均为阳性;脑脊液蛋白含量增加、细胞数增多:(3)脑血管梅毒患者MRA及DSA显示左大脑中动脉M1段闭塞;左大脑前动脉及左大脑后动脉通过皮层支向左大脑中动脉供血区代偿供血;(4)2例脊髓痨患者头颅及胸髓MRI无特殊发现,肌电图及周围神经活检不支待周围神经受损。

Dynamic respiratory compliance and total respiratory resistance were measured before surgical incision, after sternal closure in the operating room, and after arrival in the intensive care unit. The following data were recorded: age, weight, preoperative pulmonary infiltrates, preoperative mechanical ventilation, evidence of increased PBF before surgery, duration of CPB, duration of aortic cross-clamp, duration of deep hypothermic circulatory arrest, use of steroids, and volume of ultrafiltrate removed.

分别在麻醉诱导后、手术结束关胸后和返回ICU后3个时间点测定患儿的肺动态顺应性和全肺阻力,并记录患儿年龄,体重,术前胸片浸润性改变情况,术前机械通气情况,术前肺血流量增高情况,体外循环时间,主动脉阻闭时间,深低温停循环时间和体外循环中超滤量等参数。

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