血缺氧的

Vinpocetine is effective in curing cerebrovascular diseases, which can selectively improve the circulation of brain, promote energy metabolism, regulate the system function of neurotransmitter, protect brain from suffering from damage due to ischemia and anoxemia in many ways, be used in treatment of insufficiency in blood - supply, stroke and symptoms related to aging, and have special effect on recognition and memory.

长春西汀治疗脑血管病的有效药物，它能够选择性地改善大脑的血液循环，促进大脑的能量代谢，调节神经递质系统功能，多方面保护大脑免受缺血缺氧性损害，特别适用于防治脑供血不足、中风以及与衰老有关的症状，并对认知和记忆有特别的效果，目前临床应用非常广泛，现将长春西汀的药理作用及临床应用综述如下。

ObjectiveSevere traumatic patients always had a severe blood loss, for maintaining blood supply of heart and head, the gut would appear ischemic and anoxemia through the mechanisms of intestinal ischemic, reperfusion and release of mediators of inflammation and so on, which could cause functional impairment of intestinal barrier and translocation of intestinal bacterium and endotoxin, accordingly, induce the occur of SIRS (systemic inflammatory response syndrome), sepsis and MODS (multiple organ dysfunction syndrome).

目的严重创伤常伴严重失血，机体为维持心、脑的血供，肠道首先出现缺血缺氧，通过肠道缺血、再灌注、炎症介质的释放等机制，引起肠道屏障功能障碍，肠内细菌及内毒素移位，从而导致SIRS、脓毒症和MODS的发生。

(1) cerebral ischemical reperfusion injury rats'limbs motor function is variable. Acupuncture could promote lims'functional recovery.(2) PCNA masc cells is visible in cerebral ischemical semidarkness region. There is cell regeneration phenomenon. Acupuncture could strengthen injury region's PCNA expression, could profit injury recovery and functional reconstruction.(3) In ischemia semidarkness region for the model group and acupuncture group, PCNA masc cells percentage of 14days group is lower than 7days group. Along with the recovery of injury, cell multiplication is weaken.(4) In cerebral ischemia semidarkness region, there is VEGF masc cells and regeneration phenomenon. Acupuncture could strengthen injury region's VEGF expression, could profit protection after injury and blood vessel regenerate.(5) In ischemia semidarkness region for the model group and acupuncture group, VEGF masc cells percentage of 14days group is lower than 7days group. Along with the recovery of semidarkness region, ischemia and anoxemia state is getting improved, and VEGF is reduce.(6) As there are PCNA and VEGF masc cells in brain injured region, we could conclude that, after brain ischemical reperfusion injury, there are blood vessel regeneration phenomenon. Acupuncture could promote blood vessel regeneration, recovery blood supply sufficiently and quickly, and promote the recovery of brain injury region.(7)The VEGF masc cells percentage of inhibitor group is lower than acupuncture group. It state that the effect of acupuncture promote VEGF is partly depend on the existing of eNOS.

实验结论：(1)脑缺血再灌注损伤后大鼠的肢体运动功能发生改变，针刺可以促进肢体功能恢复；(2)脑缺损伤区可见PCNA阳性细胞，存在细胞再生现象，针刺可以增强损伤区PCNA的表达，有利于损伤的修复和功能重建；(3)针刺组和模型组14d时缺血损伤区PCNA阳性细胞百分比低于7d组，随着损伤逐渐得到修复，细胞增殖现象减弱；(4)脑缺血损伤区可见VEGF阳性细胞，存在内皮型细胞再生现象，针刺可以增强损伤区VEGF的表达，有利于脑损伤后保护和缺血区血管再生；(5)针刺组和模型组14d时缺血损伤区VEGF阳性细胞百分比低于7d组，随着缺血损伤的修复，缺血缺氧状态得到改善，产生的VEGF减少；(6)由于脑损伤区同时出现PCNA阳性细胞和VEGF阳性细胞，前者是增殖细胞的标志，后者是促进血管再生的重要因子，可以推断，脑缺血再灌注损伤后脑内存在血管再生现象，针刺可以促进损伤区的血管再生，更迅速而充分的恢复损伤区的血供，促进脑损伤区的修复；(7)抑制剂针刺组脑损伤区VEGF阳性细胞百分比与针刺组相比有不同程度的降低，说明针刺促进缺血损伤区VEGF表达部分依赖eNOS的存在。

White nails, found in the accident and loss of blood and shock; chronic diseases are found in anemia, hookworm disease, chronic gastrointestinal bleeding, tuberculosis hemoptysis, pulmonary heart disease and so on; as if a nail white glass, while the characteristics of liver cirrhosis; nail change White, thin, soft, was particularly prevalent in the chronic wasting disease; yellow nail is the lack of vitamin E hypothyroidism, nephrotic syndrome, and other symbolic; gray nails are often suffering from Onychomycosis, a performance for the initial stage next to the itching, Following the nail is deformed, but was dull gray; purple nails with a small red thorn is caused by hypoxia, indicating pulmonary heart disease; nail half red, half white (commonly known as a yin and yang) is not a manifestation of renal function; white nail Flocculation, or white, zinc deficiency may be, anemia or gastrointestinal system is sick; nail spots is the emergence of the performance of the poisoning; redness around the nail, mostly lupus erythematosus and in patients with dermatomyositis; nail root A blue and a half months is a reflection of peripheral circulation; obvious red nails, is the performance of heart failure; a clear and a half months, prompted the digestive system function better absorption; On the other hand, there is no clearance on a narrow or a half months, that is, Tip of the digestive system problems.

指甲变白时，急症见于失血、休克；慢性病则见于贫血、钩虫病、消化道慢性出血、肺结核咯血、肺源性心脏病等；如果指甲白得像毛玻璃一样，则为肝硬化的特征；指甲变白、变薄、变软，多见于慢性消耗疾病；指甲变黄是缺乏维生素E甲状腺功能减退、肾病综合症等象征；指甲变灰往往是患了甲癣，表现为初期甲旁发痒，继则指甲变形，失去光泽而呈灰白色；指甲青紫伴有红色小刺是缺氧引起的，预示肺心病；指甲一半红色、一半白色是肾功能不好的体现；指甲出现白点或絮状白斑，可能是缺锌、贫血或胃肠道系统有病；指甲出现黑斑是中毒的表现；指甲周围出现红斑，多见红斑性狼疮和皮肌炎患者；指甲根部的甲半月呈蓝色是末梢循环不良的反映；指甲明显发红，是心力衰竭的表现；甲半月明显者，提示消化系统吸收功能较好；反之，没有甲关月或甲半月窄小，即提示消化系统有毛病。

BACKGROUND: The copper-superoxide dismutase can not play an effective role in free radical-scavenging in the process of hypoxia or reaeration because of blood-brain barrier, whether the treating effect can be enhanced by chitosan nanoparticles is uncertain.

背景：由于血脑屏障的存在，铜超氧化物歧化酶在临床应用中往往达不到其在体外对中枢神经细胞缺氧、复氧过程中的自由基清除效果。那么能不能利用壳聚糖纳米粒这一种新的基因载体来增强铜超氧化物歧化酶的治疗效果呢？

Serum containing SSTG was obtained at different time after perorally administrated with different dose of SSTG.The cardiomyocytes were deprived of oxygen and glucose to mimic hypoxia reoxygenation injury and were treated by serum containing SSTG when reoxygenation.LDH content in supernatant was detected after reoxygenation.LDH release suppression rate was used to study the time-effect and dose-effect of serum containing SSTG.

以中药有效组分配伍方剂双参通冠方不同灌胃剂量、药后不同取血时间所得的药物血清为受试药物；培养心肌细胞，进行缺氧复氧实验，复氧同时给予不同双参通冠方药物血清处理，实验结束后取培养上清检测LDH值，以LDH释放抑制率为指标，观察含药血清药理作用强度与体内给药的量效、时效关系。

The result shows that the marked effective rate was significanthy higher in group A than in group B(P.02).The result ind icates that glucose transillumination therapy of ultraviolet- irradiated and oxygena...

说明经紫外线氧透照后的葡萄糖作为载体，有分解出氧原子以提高血氧含量改善脑组织的缺氧状态，并有激活清栓酶和川芎嗪的效应。

Using mice, Guinea pig and SD rats, models of hypoxia, cerebral infarction, cardiac infarction and blood circulation stagnation are induced, analyse the mice' life in obturating condition; measure the renewals of mice with hemiplegia; analyse Guinea pig' cardiograph at vary time; analyse the variation of the swing of S-T and T wave ; measure the index o...

选用小鼠，豚鼠，SD大鼠分别复制缺氧、脑梗塞、心肌梗塞及&血瘀&模型，记录比较小鼠在密闭环境中的存活时间，测量小鼠偏瘫恢复数，记录豚鼠不同时间心电图，比较给药前后心电图ST段和T波振幅变化的差异，测定血液流变学指标。

Symptom : 1, dark blue iris surrounding tissue hypoxia representatives, two poor blood circulation and venous stasis Central lead to high blood viscosity, Blood, impaired pancreatic microcirculation, varicose veins, arthritis, etc. 3 sclerosis, a blue and white seepage: When discovered this phenomenon, Iridovirus can refer to the map of the reflection ring again to find the most appropriate for regional and Guasha-site physiotherapy.

症状：1、虹膜周围呈深蓝色代表组织缺氧，血液循环不好2、静脉淤血环会引起血粘度高、血脂高、微循环障胰、静脉曲张、关节硬化等等3、蓝色渗白色四周全都有易手肢冰冷，有贫血、低血压现象建议：当有发现此现象时，可参照虹彩各反射图的最外环再找出相应区域作松盘与刮痧的理疗。

Result and Conclusion: Danshen's hydrosoluble compositions can improve the tolerence to anoxia of brain markedly、increase the utility of oxygen in body blood 、decrease the oxygen consumption in organism、relieve the damage of free radicles and so on.

结果与结论：丹参水溶性成分能增加脑组织的耐缺氧能力、提高机体的血氧利用率，降低机体的耗氧量和降低自由基损伤等多个途径而实现对中枢神经系统的保护。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。