血红蛋白血

The possibility of incidences forSCI becomes high with the longer course of diabetes and rising of insulin antibodylevel, insulinaemia and glycosemia.

糖尿病病程长，糖尿病患者血胰岛素水平、血糖及糖化血红蛋白升高，造成无症状脑梗死的发生率增高。

The following data were obtained and compared between resistance and responder: white blood cell,neutrophil,hemoglobulin,C-reactive protein,erythrocyte sedimentation rate,albumin,and lactate dehydrogenase.Male patients with decreased albumin may be related with resistance,but they could not be good predictors of resistance.

川崎病患儿发生IVIG耐药的可能危险因素有外周血白细胞、中性粒细胞比例、血红蛋白、C反应蛋白、血沉、血浆白蛋白、乳酸脱氢酶等，分析结果提示血浆白蛋白降低及男性可能与IVIG不敏感川崎病有关，但仅此两项指标尚不能预测IVIG不敏感川崎病的发生。

We aim to screen and identify the key potential trans-factors during hemoglobin switch. We firstly analyzed differential expression of mRNAs in erythroid induction cultures of CD34+ cells derived from normal umbilical cord blood, adult bone marrow, and bone marrow of a heterocellular hereditary persistence of fetal hemoglobin patient. We identified ZF (HCF-binding transcription factor, Zhangfei) and SH3GLB1(SH3-domain GRB2-like endophilin B1) that had differential expression in the above three cultures. Furthermore, we confirmed the different expression of the above two genes by quantitative real-time PCR.

为鉴别影响珠蛋白基因表达和开关的新的重要调节因子，我们首先分析了人脐带血、正常成人骨髓和异细胞型胎儿血红蛋白持续存在综合症患者骨髓细胞红系诱导培养物中基因表达的差异，发现ZF(HCF-binding transcription factor，Zhangfei)和SH3GLB1（SH3-domain GRB2-like endophilin B1）在这三种不同来源的红细胞内具有显著的表达差异，并通过实时定量PCR方法验证了差异的真实性。

In this study, Mono-nuclear cells containing hematopoietic stem/progenitor cells were isolated from umbilical cord blood of normal full-term deliveries, healthy adult and heterocellular HPFH patient bone marrow by density gradient centrifugation. After simple purification and expansion in vitro, MNCs were induced to erythroid cell differentiation using different culture systems and cytokines including Epo, IL-3 and GM-CSF.

本研究首先利用密度梯度离心方法，从正常成人和异细胞型遗传性胎儿血红蛋白持续存在综合症家系患者的骨髓组织、健康足月正常分娩胎儿脐带血中分离得到了含有造血干／祖细胞的单个核细胞(Mono-Nuclear Cell，MNC)，进行初步纯化及体外扩增后，组合使用Epo、IL-3、GM-CSF等细胞因子，将造血干／祖细胞向红系方向进行诱导培养。

He was previously healthy until 2000 when he developed petechiae and purpura on both legs. In 7/2000, he was diagnosed with thrombocytopenic purpura (platelets 36×10*9/l, but normal WBC/Hgb/LFTs/renal function/urinalysis).

他一直很健康，2000年的时候突然发现两条腿上有血瘀点和紫癜。2000年7月，他被诊断患有血小板减少性紫癜（血小板数，36×10*9/l，但是白细胞/血红蛋白/肝功能试验/肾功能/尿检均正常）。

The path-physiological mechanism of ICH is complicated, which includes the high intracranial pressure caused by hematom mechanical pressure, the lesion by the decrease of regional cerebral blood flow surrouding the hematom, even regions adjacent to the hematom, Meanwhile, the materials released from hematom including ferrohemoglobin, thrombase, plasma protein and platelet, leucocyte, glusate not only directly injury neurons but also blood brain barrier.

脑出血的病理生理学机制复杂，其中包括血肿的机械压迫所造成的持续的脑缺血性损害；血肿分解后产生的血红蛋白、凝血酶、血浆蛋白、血小板和白细胞、谷氨酸、自由基等毒性物质不仅可直接损伤神经元，而且可损害血脑屏障加重脑水肿。

Methods Eighty patients of open heart surgeries performed recently were divided randomly into two groups, group A:heparin coated artery filter, group B:non-heparin coated. Platelets, hemoglobin, haematocrit, and activated coagulation time were measured on 60 minutes of extracorporeal circulation and after extracorporeal circulation and ultrastructure of filter screen was observed after extracorporeal circulation by electron microscope.

80例体外循环心脏直视手术患者随机分为两组，每组40例。A组：用肝素涂层动脉过滤器，B组：用非肝素涂层动脉过滤器；并于不同的时间点观察血小板计数、血红蛋白、红细胞压积、激活凝血时间和过滤器内网在电子显微镜下的改变。

Blood samples were taken for the measurement of RBC, Rb, Hct, plasma EPO concentration, whole blood/plasma viscosities, the animals were then catheterized to record mean pulmonary arterial pressure and demised to calculate the ratioCRV/D. Percentage of vascular wall thickness and muscularization of non-muscular pulmonary arteriole were examined microscopically.

取血样测定红细胞数、血红蛋白、红细胞压积、血浆EPO浓度、全血／血浆翻度，颈外静脉插管测定平均肺动脉压力；动物处死后计算右心室／〔RV/〕评价右室肥厚程度；光镜观察肺小动脉管壁厚度百分比、肺非肌性小动脉肌化程度。

Hemolysis was evaluated in vitro through measuring erythrocyte lyses and ferrohemoglobin freeing degree with indirect contact method.

采用溶血试验检查材料对血液红细胞的溶解作用，测定红细胞溶解和血红蛋白游离的程度。

The treatment comparison by using Chinese TANG Kidney capsule and Western medicine TANG SHI PIN showed: the kidney capsule can lower the values of the blood sugar, blood fat, series of micro-protein un urine and carbon monoxide in plasma, thus the function of kidney can be improved, and prolong the process of deadness and hardening of the affected kidney small cell fibre.

利用该模型选择中药糖肾胶囊与西药糖适平对照治疗研究，结果显示：糖肾胶囊能降低糖尿病肾病大鼠的血糖、血脂、尿素氮、肌酐、尿系列微量蛋白及血一氧化氮等指标，从而减轻糖尿病肾病大鼠肾小球的高灌注高滤过，降低糖化血红蛋白含量，减轻非酶糖基化，改善肾功能，降低血脂、内皮素、调节血栓素、前列腺素水平，有抗脂质过氧化损伤的作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。