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血红蛋白

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METHODS: Five patients with an intracorporeal centrifugal left ventricular VAD, 10 patients with an axial LVAD and seven patients with a paracorporeal biventricular assist device were analysed preoperatively and 3 days (3.0+/-0.4 days, early), 2 weeks (14+/-1 days, intermediate) and 2 months (62+/-5 days, later) after VAD implantation for haptoglobin, haemopexin, free haemoglobin in plasma, LDH, total haemoglobin, haematocrit and transfusion requirements.

共计纳入使用体内离心性左室VAD患者5例、使用近心性LVAD患者10例、使用外置式双心室辅助装置患者7例,分析其在VAD植入术前、术后3天(3.0+/-0.4 天,早期)、2周(14+/-1 天,过渡期)和 2月(62+/-5天,后期)的结合珠蛋白,血红素结合蛋白,血浆中游离血红蛋白, LDH,总血红蛋白,红细胞压积和输血量。

Results There are 89 cases patients with left ventricle pachynsis in 186 cases patients with chronic kidney failure,the incidence is 47.8%,the occurance of left ventricle pachynsis to chronic kidney failure present positive correlation with systolic pressure (P 0.01 ),positive correlation with age(P.05),n...

慢性肾衰竭患者左心室肥厚的发生与收缩压呈正相关(P 0 1 ),与年龄呈正相关(P 0 5 ),与血浆白蛋白浓度呈负相关(P 0 5 ),与血红蛋白呈负相关(P 0 5 ),与红细胞压积呈负相关(P 0 1 )。结论慢性肾衰竭并左心室肥厚与收缩压、年龄、血浆白蛋白、血红蛋白、红细胞压积等因素相关

Result 212 2 model current of diabetic part blood changes learn haemoglobin of index, hollow blood sugar, saccharify all apparent heighten, contrast with health group compare difference to have remarkable statistical sense (P.01); blood current changes learn haemoglobin of each index and hollow blood sugar, saccharify to show positive to involve a sex.

结果212例2型糖尿病患者部份血液流变学指标、空腹血糖、糖化血红蛋白均明显增高,和健康对照组比较差异有显著的统计学意义(P.01);血液流变学各项指标和空腹血糖、糖化血红蛋白呈正相关性。

Previous studies by others and this laboratory on the allosteric effect of hem oglobins have suggested that the electrostatic replusive cavity at the center of tetrameric moiety plays a substantial role in regulating O2 transport prope rties, including chloride binding, and Bohr effect .

中文摘要过去对血红蛋白异位调节效应的研究指出,在血红蛋白四合体中央空腔的区域的静电排斥效应对分子机能的调节如氧合时氯离子的键结和波尔效应,扮演著一个很重要的角色。

In attempt to obtain a further insight into the contribution of charged residues to other allosteri c properties , in this study we designed and synthesized a site directed mutan t , b82 Lys-Asn , for examing influencs the tetrameric stability and enthalpit ic change in O2 binding of human adult hemoglobin.

本研究焦点放在血红蛋白中央空腔中,带有正电残基的其中一个位置,b82 Lysyl ,来研究其正电离子效应与人类血红蛋白氧合反应热及四合体安定性的相关。针对这个目标,我们利用电脑做胺基酸序列排列比对和分子结构的模拟,选择以Asparaginyl残基取代Lysyl残基。

By O2 equilibrium, gel permission chromatography, and autooxidation analyses, we have investigated that the pos itively charge of b82 Lysyl residue is indeed involved in the exhothermic O2 b inding characteristics and somewhat stabilize the tetrameric heme moiety of Hb A.

其纯度以可见光谱和血色素电泳鉴定,并以氧合平衡曲线的测定,胶质层析和氧化速率的分析检视重组血红蛋白之性能。实验结果显示β82Lysyl残基所带的正电性确实影响血红蛋白氧合时的放热反应与其四合体的安定性。

HbJ Tashikuergan was firstly reported in the world, and CD8and CDs8/9 were firstly discovered in China.Conclusion:The types and distribution of abnormal hemoglobin and thalassemia in Kashi district were? different from those in other areas of our country,and also unsimilar to our neighbour countries.

对喀什地区血红蛋白病的研究表明,异常血红蛋白和地中海贫血的类型特点既有别于我国其它地区,又与邻近的中亚等国不完全相同,形成了该地区独有的遗传特征。

Compared with the surface-dwelling rodents, the higher RBC, HGB and HCT as well as lower MCV, MCH and MCHC in Gansu Zokor have possible roles in their adaptation to hypoxia environment.

与地面生活的啮齿动物低氧适应后血象相比,甘肃鼢鼠红细胞数量多,红细胞压积大,血红蛋白浓度高,红细胞膜表面积大,血红蛋白的利用率较高,可能是对低氧环境适应的一种途径。

The most popular technique utilizes blood oxygenation level dependent contrast, which is based on the different magnetic properties of oxygenated and deoxygenated blood.

其中基于氧合血红蛋白和脱氧血红蛋白的磁化率差异的血氧水平依赖性对比度的fMRI 技术在脑功能的研究中已经成为一种最重要的工具。

NIRS has shown great potential in examining functional brain activity during cognitive tasks by enabling an independent measurement of changes in the concentration of the oxygenated hemoglobin (HbO2) and the deoxygenated hemoglobin in cortex tissue based on differential absorption at multiple wavelengths.

基于氧合血红蛋白(HbO_2)和脱氧血红蛋白对多个波长的近红外光的不同吸收,NIRS可以提供对脑组织中HbO_2和Hb浓度相对变化的独立测量,因而在大脑功能活动的检测领域表现出了巨大潜能。

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