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A number of studies have demonstrated impaired endothelium-dependent vasodilatation in animals and humans with hyperhomocysteinemia.

高同型半胱氨酸血症的病人和动物模型均存在有明显的血管内皮依赖性舒张功能的损害。

In this context, we have reported recently that the volume of myocardial tissue occupied by perimysial and endomysial collagen was lower in hypertensive patients with HF and depressed ejection fraction, than in hypertensive patients with HF and preserved ejection fraction and normotensive subjects.56 Of interest, the interstitial and perivascular accumulation of collagen fibres was abnormally high in the two groups of patients.

在这种情况下,我们已经说了占用体积perimysial心肌组织人肌内膜胶原水平低的高血压患者用高频和沮丧的射血分数在高血压患者的心力衰竭和保存被罚出场分数与正常血压subjects.56舒张压的利息、间质和血管堆积过高的胶原纤维是在两组病人。

The hypercholesterolemic rats were selected to imitate early stage of human atherosclerosis The effects and mechanism of n-3 PUFA on endothelium were investigated with the following parameters: the morphological appearance and arrangement of endothelium stained by Ag, in vitro endothelium-dependentrelaxation of aortic ring, endothelial permeability test using Even′s Blue, blood lipid and body weight in one-week intervals, excitative and emissive spectrum of RBC membrane labeled by DPH (1, 6-Diphenyl-1, 3, 5-hexatriene), fluidity of RBC membrane, plasma and RBC membrane LPO

在整体和离体水平,选用大鼠高脂血症模型模拟动脉粥样硬化早期状况。用114只大鼠多指标着重研究n-3多不饱和脂肪酸在高脂血症状态下对内皮的保护作用,以探讨其预防动脉粥样硬化的机理。所采用指标包括:浸银法观察内皮细胞排列与形态;离体血管环观察内皮依赖性舒张;伊文氏蓝染料法观察内皮通透性。为探讨作用机理,进行了血脂和体重的动态监测、DPH(1,6-二苯基-1,3,5,乙三烯)标记红细胞膜的荧光光谱测定、红细胞膜流动性测定、血浆和红细胞膜脂质过氧化物测定。

To explore the regulatory mechanism of muscular ultramicrostructures of the outflow segments on blood flowing out from the cerebral bridging veins. Methods Bridging veins were obtained from patients suffering from nonvenous disorder diseases of the central nervous system.

目的 观察人脑桥静脉流出端管壁的肌性超微结构,揭示该段血管的收缩和舒张特性,探讨其对颅内静脉血液流出的调节机制。

Cardiac hypertrophy and extracellular matrix remodeling happened as a result of chronic overrange of pressure in heart and hypervolaemia which lead to damage of relaxation and compliance of heart.Drugs including renin-angiotensin converting enzyme inhibitor,angiotensin receptor blocker,aderergic receptor blocker,aldrosteron antagonism,tatins endothelin receptor blocker pancreatic kiniogenase and calcalium channel blocker,can delay or reverse the remodeling by several mechanisms.

主要表现为心脏在慢性超负荷的压力、容量作用下发生的病理改变致使左室肥厚组织胶原结构发生改变,导致心肌顺应性降低,舒张功能受到损害;作用于肾素-血管紧张素系统的药物及肾上腺素受体阻滞剂、醛固酮拮抗剂、他汀类药物、内皮素受体拮抗剂、胰激肽原酶、钙通道阻滞剂等药物通过不同途径和机制延缓和逆转左心室重构。

Methods 50 patients with diabetes and contrast group were observed, with transcrianial color Doppler flow imaging, cerebral blood stream velocity; pulsative index,resistive index and S/D were calculated of middle cerebral artery, anterior cerebral artery and posterior cerebral artery Results (1)Changes of cerebral blood stream velocity were non-specifitical in blood waves of TCDFI, but VE was reduced.

经临床诊断糖尿病50例,行TCDFI检测大脑中动脉、大脑前动脉、大脑后动脉等血管的血流速度指标及搏动指数、阻力指数,收缩期血流速度/舒张末期血流速度及频谱形态分析与健康组对照比对分析。结果(1)TCDFI频谱中,血流速度的变化,Vmax是非特异性的,而VE是明显下降的。

Methods 50 patients with diabetes and contrast group were observed, with transcrianial color Doppler flow imaging, cerebral blood stream velocity; pulsative index,resistive index and S/D were calculated of middle cerebral artery, anterior cerebral artery and posterior cerebral artery Results (1)Changes of cerebral blood stream velocity were non-specifitical in blood waves of TCDFI, but VE was reduced.

目的 为探讨糖尿病对脑血管的,而对脑动脉血流动力学进行对比。经临床诊断糖尿病50例,行TCDFI检测大脑中动脉、大脑前动脉、大脑后动脉等血管的血流速度指标及搏动指数、阻力指数,收缩期血流速度/舒张末期血流速度及频谱形态分析与健康组对照比对分析。结果(1)TCDFI频谱中,血流速度的变化,Vmax是非特异性的,而VE是明显下降的。

Time to ischemic stroke and stroke in the same territory of the stenotic essel was compared in patients grouped by mean systolic blood pressure and mean diastolic blood pressure during the study.

进一步分析的是以病变的严重程度和狭窄的位置为根据。在试验过程中,把病人按照平均收缩压和平均舒张压进行分组,对比缺血性中风和狭窄血管相关区域的中风的时间。

NEW YORK Mar 11 - An infusion of milrinone, a phosphodiesterase inhibitor that combines vasodilating and inotropic properties, reverses the cerebral vasospasm that can accompany an aneurysmal subarachnoid hemorrhage, French researchers report in the March issue of Stroke.

法国研究者在三月《中风》期刊上报道了他们的新发现:米力农(一种磷酸二酯酶抑制剂,具有舒张血管和影响肌肉收缩力的特性)能逆转动脉瘤致蛛网膜下腔出血后的脑动脉痉挛。

Though arginine is required to make nitric oxide, and nitric oxide is required to dilate blood vessels and have an erection,"that doesn't mean eating something that is rich in citrulline will make enough arginine that it will lead to better penile erections," Goldstein says.

尽管生成一氧化氮需要精氨酸,而舒张血管跟勃起需要一氧化氮,Goldstein说:&那不意味着吃点富含瓜氨酸的东西就会产生总够的精氨酸,从而导致阴茎更好的勃起&。

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