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血管舒张

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Methods: Fresh saphena rings were sudied in organ chamber after incubating with Krebs-Henseleit bicarbonate solutions, FWM, KH with 0.1mmol/L NCR, FWM with 0.1mmol/L NCR at 37℃ for 1 hour. Precontraction induced by prostaglandin F2 (U4661930nmol/L) and endothelium-dependent relaxation induced by calcium ionophore A23187 l0^(-10~l0^(-6) mol/L were measured in the presence of indomethacin (7μmol/L) and LNNA (300μmol/L). Result: No significant changes were found in the 4 groups under the light microscope.

采用器官槽法研究在37℃有氧条件下用重碳酸盐缓冲液、含0.1mmol/L NCR的KH液、FWM液、含0.1mmol/L NCR的FWM液中浸泡血管环1h后,再用7μmol/L吲哚美辛和300 μmol/L N-硝基-L-精氨酸作用后,检测30 nmol/L U46619及不同浓度A23187引发的血管收缩舒张反应。

The variation of plasma vasoactive peptide concentration was not only related to UAP attack but also significant to the maintance coronary diastole and corculation.

UAP的发生与血管活性肽的变化密切相关,血管活性肽对维持冠脉舒张和循环有重要意义。

The purpose of this study was to investigate the vasorelaxing effect of vasonatrin peptide on human intramammary artery.The vasorelaxing effect of VNP on HIMA was measured by means of perfusion in vitro. The effects of HS-142-1, TEA, 8-Br-cGMP and methylene blue were also observed.

为了研究血管钠肽对人乳内动脉(human intramammary artery, HIMA)的舒张作用及其机制,采用离体血管灌流的方法,观察VNP对内皮完整和去内皮HIMA的舒张作用,以及HS-142-1、TEA、8-Br-cGMP和镁蓝对这一过程的影响。

Constituting a tube; having hollow tubes同义词:tubular, cannular, tubelike, tube-shaped vasoactive

a。 血管活性的,(尤指在血管的舒张或收缩方面)作用于血管的,影响血管的 vasoconstriction

Objective Endothelial dysfunction, characterized by impaired endothelium-dependent vasodilatation, is now considered as the common path toward cardiovascular disease.

内皮细胞损伤导致的血管内皮功能障碍目前被认为是诱发许多心脑血管疾病的共同环节,其中血管内皮舒张功能的受损是血管内皮功能障碍的重要特征之一。

By using β-NADPH-diaphorase histochemical staining technique,wefound for the first time that NOS activity was detected in the epithelium of airpathway and endothelium of vessels but was not detected in the small vessels(ID<100μm),and the NOS express in pulmonary vascular endothelium of preascitic andascitic broilers were elevated,especially in the endothelium and smooth muscle layer ofsmall vesseles with thicker walls and of muscularized nomuscular artery in asciticbroilers.

本研究从田间自然发生腹水症的肉鸡群中选取正常肉鸡、亚临床腹水鸡和腹水鸡为实验对象,通过比较这三种肉鸡血流动力学、心电图、动静脉血血气、肺外动脉舒张反应性、肺血管结构以及肺组织一氧化氮合酶的活性和分布等方面的不同,探讨了肺动脉舒张能力在肉鸡肺动脉高压形成中的作用和机制。

Our results indicated that (1) aortic rings with and without endothelium precontracted by NE to decreased pH induced a relaxation; aortic rings with and without endothelium to increased pH induced a contraction; there is no significant difference in presence and absence of endothelium .(2)NO levels had no significant change in isolated aortic rings presence and absence of endothelium to decreased pH and increased pH ;(3)sulfite levels in isolated aortic rings with endothelium reduced to decreased pH and increased pH. sulfite levels in aortic rings without endothelium had no remarkable change.

结果:①NE预收缩后,pH值降低对内皮完整和去除内皮胸主动脉血管环呈舒张作用;pH值升高对内皮完整和去除内皮胸主动脉血管环呈收缩作用;内皮完整组与去内皮组相比无显著性差异;②pH降低和升高对内皮完整和去除内皮血管环中NO含量无显著性影响;③pH降低和升高均可使内皮完整血管组织中亚硫酸盐含量减少,对去内皮血管中亚硫酸盐无显著性影响。

Glyceryl trinitrate induced dilatation: GTN, high sensitive C reactive protein, tHcy, serum folate, red cell folate and lipids.

干预前、后分别检测血管内皮功能、血管平滑肌功能(硝酸甘油介导的血管平滑肌舒张GTN)、高敏C反应蛋白、血浆总高半胱氨酸、血浆红细胞叶酸盐和血脂。

Glyceryl trinitrate induced dilatation: GTN, high sensitie C reactie protein, tHcy, serum folate, red cell folate and lipids.

干预前、后分别检测血管内皮功能、血管平滑肌功能(硝酸甘油介导的血管平滑肌舒张GTN)、高敏C反应蛋白、血浆总高半胱氨酸、血浆红细胞叶酸盐和血脂。

Then the responses of artery to phenylephrine acetylcholine, sodium nitroprusside and norepinephrine were studied.

结果:转基因血管内皮细胞的增殖较对照组活跃,动脉的内皮依赖性舒张反应较强,10 -6mol/L 的乙酰胆碱引起的舒张为33-08%±10-01%,对照组为- 17-57%±5-59%,P< 0-01 。

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这一模式非常关注商人的网络信用基础。

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