血管舒张

We hypothesized that nitrite would have a greater dilator effect in capacitance than in resistance vessels because of lower oxygen tension and that resistance-vessel dilation should become more pronounced during hypoxemia.

我们猜测，因为较低的氧分压，容量血管和阻力血管相比，对亚硝酸盐有更强的舒张作用。而在缺氧状态下，阻力血管的舒张更加明显。

Treatment group was treated with valsartan and control group was treated without drugs such as ACEI or ARBs. Pmax,Pd and LADd,LVDs,LVDd were measured and compared before treatment and 6 months' after treatment. Result: There was significant difference in Pd , Pmax and LADd between treatment group and control group .

治疗组给予缬沙坦治疗，对照组给予非血管紧张素转化酶抑制剂类及非血管紧张素受体拮抗剂类降压药治疗，观察药物治疗6个月前后心电图中的Pmax和Pd及超声心动图中的左房舒张末内径、左室收缩末内径、左室舒张末内径的变化。

The endothelium-dependent vasodilation is impaired in patients with hypertension and the high-frequence ultrasound can be used to detect endothelial dysfunction.

高血压患者存在血管内皮依赖性舒张功能失调，高频超声能准确可靠地检测血管内皮依赖性舒张功能。

ET and NO are the biology regulatory factors produced by vascular endothelial cell.ET is a peptide with vasoconstrictive and vasodilator effect produced by endothelial cells,and NO as a powerful endothelium-derived relaxing factor,has a strong role in dilation of blood vessels.

ET和NO是血管内皮细胞产生的生物调节因子，ET是由内皮细胞产生的一种多肽，具有缩血管和扩血管作用，而NO为一种强有力的血管内皮细胞舒张因子，具有强烈扩张血管作用。

The purpose of this study was to compare the vasodilating effects of angiotensin-(1-7) [Ang-(1-7)] on the different vessels and to clarify its mechanisms by using relaxing responses of preconstricted vascular rings.

实验采用兔外周动脉离体标本，在预收缩血管后，用血管紧张素[angiotensin--(1--7)，Ang--(1--7)]舒张血管，比较Ang--(1--7)对外周各血管床的舒张效应并分析其产生机制。

These results indicate that apelin-13 relaxes the thoracic aorta in the two groups and the response of vasodilatation is enhanced in the rat thoracic aortas from the 2K1C hypertension group. It may be an important protecting factor and play an important role in the protection of blood vessel.

Apelin-13具有显著的舒张主动脉的作用，并且对高血压大鼠血管环的舒张作用更强，提示Apelin-13在血管的保护作用中扮演了重要角色。

Effects of H_2O_2 on the tension of isolated aortic rings of rat As above methods,Our results indicated that (1) aortic rings with endothelium precontracted by NE to 10000μmol/L H_2O_2 induced a relaxation; aortic rings with endothelium to 100μmol/L H_2O_2 induced a significant contraction;H_2O_2 induced the same effects in aortic rings without endothelium, there is significant difference in presence and absence of endothelium.

双氧水对大鼠离体血管环张力的影响方法同2，结果：①NE预收缩后，加入10000μmol／L H_2O_2，内皮完整血管环表现为舒张作用；加入100μmol／L H_2O_2后血管环表现为收缩作用；H_2O_2对去内皮的血管环同样具有上述作用，与内皮完整组相比差异显著；②10000μmol／L H_2O_2可使得内皮完整及去内皮血管环中NO含量升高；100μmol／L H_2O_2可使得NO含量降低。

ONOO〓 had direct vasoactive effect for relaxation of precontracted isolated pulmonary artery. Relaxing action of ONOO〓 was weak and was negtively regulated by endothelial cells, further supporting the notion that ONOO〓 may be involved in pulmonary hypertension in the early stage of ES.

用离体血管环检测张力方法，发现ONOO〓具有一定的舒张肺动脉作用，但舒张效应较弱，并受到血管内皮细胞的抑制性调节；抑制K〓通道和PARS活性可增强ONOO〓对离体兔肺动脉的舒张作用。

Our results indicated that (1)SO_2 derivatives could dose-dependently relax the isolated aorta rings with or without endothelium precontracted by NE, no difference was found for the rings with and without endothelium;(2)Levels of cAMP and 6-Keto(PGI_2) in isolated aortic rings were increased by SO_2 derivatives in a dose-dependent way, which were independent of endothelium;(3)SO_2 derivatives decreased cGMP levels in the rings, but not significantly; The decrease of cGMP levels was also independent of endothelium;(4)No changes of TXB_2 in rings with or without endothelium were observed;(5)Whether presence or absence of endothelium, cAMP/cGMP and 6-Keto/TXB_2 ratios were increased significantly.

结果：①SO_2衍生物对去甲肾上腺素预收缩的内皮完整和去除内皮的大鼠胸主动脉血管环均呈浓度依赖性舒张作用，且其张力变化在内皮完整与去内皮的血管环之间无显著性差异；②SO_2衍生物可引起血管组织中cAMP、6-Keto(即PGI_2)含量剂量依赖性增加，其增加程度与内皮无关；③SO_2衍生物对血管环cGMP含量呈降低趋势但在统计学上无显著意义，且对去除内皮血管无显著影响；④SO_2衍生物对去内皮或内皮完整血管环的TXB_2含量均无明显影响；⑤无论是否去除内皮，SO_2衍生物均可引起cAMP／cGMP和6-Keto／TXB_2比值显著升高。

Endothelium-independent relaxations were identical in all groups.

所有实验组小鼠非内皮依赖的血管舒张反应相同。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。