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These substances are strong vasodilator agent, can reduce peripheral vascular resistance and coronary heart against the human body catecholamine pressor substances, such as the role, but also to promote the excretion of sodium, so that blood pressure dropped.

这些物质均为较强的血管舒张剂,能减少外周血管和心脏冠状动脉的阻力,对抗人体内儿茶酚胺等升压物质的作用,又能促进钠盐的排泄,从而使血压下降。

Ang II is a vasoconstrictor and growth-promoting substance, whereas bradykinin is a potent vasodilator and growth inhibitor.

Ang II 是一种使血管收缩和促进生长的物质,而BK 是使血管舒张和抑制生长的。

Coronary disease ; Endothelium ; vascular ; Vasodilatation ; Risk factors

冠状动脉疾病;内皮;血管;血管舒张功能;危险因子

In this latter case, men may have the advantage over women because of less AT2R-mediated vasodilation.

在后面几种情况下,由于血管紧张素II介导的血管舒张弱于女性,男性可以从中获益。

The NO content and the NOS activity were down in the PIH pregnant women placenta.This showed that the ghrelin regulated the VEGF and influenced the the NO down.And the placenta angiospasm,blood pressure highten, and the PIH were caused also by this. The ghrelin,VEGF,Flt-1,NO and NOS were detected by the SP-immunochemistry, RQ-PCR,cell culture in vitro,ASODN and nitrate reductase in the normal pregnancy,PIH placenta and the cultured HUVEC antisense blocking ghrelin in vitro.

结果证实:PIH孕妇胎盘组织中Ghrelin,VEGF、Flt-1蛋白和mRNA水平下降与正常孕妇比较有显著性差异p<0.05提示在PIH发病过程中Ghrelin可能对VEGF,Flt-1蛋白和mRNA的表达具有下调作用,进而影响胎盘血管网的形成和发育;NO含量与NOS活力水平在PIH孕妇胎盘组织中下降,提示Ghrelin可能通过下调VEGF的表达进一步影响血管舒张因子NO水平下降,进而引起胎盘血管痉挛,血压升高,最终导致PIH的发生。

Results: Extract B of mallotus furetianus lowered MDA, TC, TG, LDL-C levels of AS serum, elevated NOS, SOD activity, increased HDL-C/LDL-C, increased discharge of TB from bile, improved pathological changes of vascular tissue, increased the ability of vasodilation of the endothelium-dependence.

结果:山苦茶B降低AS大鼠血清MDA、TC、TG、LDLC水平,提高NOS,SOD活性;增加HDLC/LDLC,增加胆汁中TB的排出,改善血管组织病理变化,增强内皮依赖性血管舒张能力。

Methods The plasma levels of CGRP in 59 cases of normal pregnant women, 57 cases of PIH, and 10 cases of nonpregnant women were determined with a sensitive radioimmunoassay.

是由周围血管神经纤维末梢和甲状腺C细胞合成、分泌的,广泛分布在神经组织以及某些器官中,是体内较强的血管舒张物质,参与血压动态平衡的维持及器官血流的调节[2,3]。

AIM: To study the functional changes of perivascular adipose tissue in SHR and the effects of statins therapy.

目的:观察自发性高血压大鼠血管外周脂肪组织释放血管舒张因子功能的改变及他汀类药物干预的影响。

Methods The effects of three vasodilators on the potassium chloride, norepinephrine concentration-response curves and precontracted rabbit aorta were investigated.

以离体兔主动脉条观察该三种血管舒张药对氯化钾、去甲肾上腺素量效曲线及预收缩血管的影响。

Bradykinin is belieed to be the most important mediator of HAE attacks, the authors explain, and bradykinin B2 receptors (BR-2) mediate most physiological actions of kinins, including asodilation.

目前认为缓激肽是遗传性血管水肿发作的最重要的介导物,作者解释说,而缓激肽B2受体(BR-2)介导了包括血管舒张等激肽的大部分生理活动。

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